<?xml version="1.0" encoding="UTF-8"?><xmi:XMI xmlns:pos="http:///org/u_compare/shared/label/penn/pos.ecore" xmlns:grammatical="http:///org/u_compare/shared/label/penn/function/grammatical.ecore" xmlns:general="http:///org/u_compare/shared/label/penn/pos/general.ecore" xmlns:cas="http:///uima/cas.ecore" xmlns:stanford="http:///org/u_compare/shared/label/stanford.ecore" xmlns:semantic2="http:///uk/ac/nactem/semantic.ecore" xmlns:bioie="http:///org/u_compare/shared/label/penn/pos/bioie.ecore" xmlns:function="http:///org/u_compare/shared/label/penn/function.ecore" xmlns:tcas="http:///uima/tcas.ecore" xmlns:bio="http:///org/u_compare/shared/semantic/bio.ecore" xmlns:syntactic="http:///org/u_compare/shared/syntactic.ecore" xmlns:comparable="http:///org/u_compare/shared/comparable.ecore" xmlns:examples="http:///org/apache/uima/examples.ecore" xmlns:label="http:///org/u_compare/shared/label.ecore" xmlns:xmi="http://www.omg.org/XMI" xmlns:general2="http:///org/u_compare/shared/label/penn/bracket/general.ecore" xmlns:shared="http:///org/u_compare/shared.ecore" xmlns:fragment="http:///org/u_compare/shared/document/fragment.ecore" xmlns:document="http:///org/u_compare/shared/document.ecore" xmlns:bracket="http:///org/u_compare/shared/label/penn/bracket.ecore" xmlns:text="http:///org/u_compare/shared/label/penn/function/text.ecore" xmlns:structure="http:///org/u_compare/shared/document/structure.ecore" xmlns:text2="http:///org/u_compare/shared/document/text.ecore" xmlns:release="http:///org/u_compare/shared/label/penn/pos/release.ecore" xmlns:semantic="http:///org/u_compare/shared/semantic.ecore" xmlns:nontext="http:///org/u_compare/shared/document/nontext.ecore" xmlns:conll="http:///org/u_compare/shared/label/conll.ecore" xmlns:chemical="http:///org/u_compare/shared/semantic/chemical.ecore" xmlns:semantic3="http:///org/u_compare/shared/label/penn/function/semantic.ecore" xmlns:release2="http:///org/u_compare/shared/label/penn/bracket/release.ecore" xmlns:coindex="http:///org/u_compare/shared/label/penn/coindex.ecore" xmi:version="2.0"><cas:NULL xmi:id="0"/><cas:Sofa xmi:id="1" sofaNum="1" sofaID="_InitialView" mimeType="text" sofaString="Use of gene fusions to study expression of cysB, the regulatory gene of the cysteine regulon. &#10;Strains of escherichia coli were constructed in which the lacZ gene is fused to cysB, the positive regulator gene of the cysteine regulon. The fusion strains were used to study the regulation of the cysB gene by assaying the fused lacZ gene product. The introduction of a cysB allele, either on a plasmid or on an episome to the fusion strains, resulted in the decrease of beta-galactosidase activity. This implies that the cysB gene expression is autoregulated by its own product. The direction of cysB gene transcription was determined to be clockwise. "/><cas:FSArray xmi:id="339" elements="343 352"/><cas:FSArray xmi:id="346" elements="240"/><cas:FSArray xmi:id="355" elements="26"/><cas:FSArray xmi:id="361" elements="364"/><cas:FSArray xmi:id="367" elements="33"/><cas:FSArray xmi:id="373" elements="377 386"/><cas:FSArray xmi:id="380" elements="44"/><cas:FSArray xmi:id="389" elements="55"/><cas:FSArray xmi:id="395" elements="399 408"/><cas:FSArray xmi:id="402" elements="77"/><cas:FSArray xmi:id="411" elements="66"/><cas:FSArray xmi:id="417" elements="420"/><cas:FSArray xmi:id="423" elements="84"/><cas:FSArray xmi:id="429" elements="433 442"/><cas:FSArray xmi:id="436" elements="95"/><cas:FSArray xmi:id="445" elements="106"/><cas:FSArray xmi:id="451" elements="455 464"/><cas:FSArray xmi:id="458" elements="284"/><cas:FSArray xmi:id="467" elements="306"/><cas:FSArray xmi:id="473" elements="476"/><cas:FSArray xmi:id="479" elements="117"/><cas:FSArray xmi:id="485" elements="488"/><cas:FSArray xmi:id="491" elements="131"/><cas:FSArray xmi:id="497" elements="501 510"/><cas:FSArray xmi:id="504" elements="142"/><cas:FSArray xmi:id="513" elements="124"/><cas:FSArray xmi:id="522" elements="0 26 33 44 55 66 77 84 95 106 117 124 131 142 0 0 0 0 0 0 0 0 0 0"/><tcas:DocumentAnnotation xmi:id="8" sofa="1" begin="0" end="650" language="x-unspecified"/><tcas:DocumentAnnotation xmi:id="21" sofa="1" begin="0" end="650"/><examples:SourceDocumentInformation xmi:id="13" sofa="1" begin="0" end="650" uri="/6792186.txt" offsetInSource="0" documentSize="650" lastSegment="true"/><semantic:LinkedAnnotationSet xmi:id="343" linkingRelation="349" linkedAnnotations="346"/><semantic:LinkedAnnotationSet xmi:id="352" linkingRelation="358" linkedAnnotations="355"/><semantic:LinkedAnnotationSet xmi:id="364" linkingRelation="370" linkedAnnotations="367"/><semantic:LinkedAnnotationSet xmi:id="377" linkingRelation="383" linkedAnnotations="380"/><semantic:LinkedAnnotationSet xmi:id="386" linkingRelation="392" linkedAnnotations="389"/><semantic:LinkedAnnotationSet xmi:id="399" linkingRelation="405" linkedAnnotations="402"/><semantic:LinkedAnnotationSet xmi:id="408" linkingRelation="414" linkedAnnotations="411"/><semantic:LinkedAnnotationSet xmi:id="420" linkingRelation="426" linkedAnnotations="423"/><semantic:LinkedAnnotationSet xmi:id="433" linkingRelation="439" linkedAnnotations="436"/><semantic:LinkedAnnotationSet xmi:id="442" linkingRelation="448" linkedAnnotations="445"/><semantic:LinkedAnnotationSet xmi:id="455" linkingRelation="461" linkedAnnotations="458"/><semantic:LinkedAnnotationSet xmi:id="464" linkingRelation="470" linkedAnnotations="467"/><semantic:LinkedAnnotationSet xmi:id="476" linkingRelation="482" linkedAnnotations="479"/><semantic:LinkedAnnotationSet xmi:id="488" linkingRelation="494" linkedAnnotations="491"/><semantic:LinkedAnnotationSet xmi:id="501" linkingRelation="507" linkedAnnotations="504"/><semantic:LinkedAnnotationSet xmi:id="510" linkingRelation="516" linkedAnnotations="513"/><shared:ExternalReference xmi:id="41" namespace="GREC Concepts" ID="Gene"/><shared:ExternalReference xmi:id="52" namespace="GREC Concepts" ID="Gene"/><shared:ExternalReference xmi:id="63" namespace="GREC Concepts" ID="Gene"/><shared:ExternalReference xmi:id="74" namespace="GREC Concepts" ID="Mutant_Bacteria"/><shared:ExternalReference xmi:id="92" namespace="GREC Concepts" ID="Gene"/><shared:ExternalReference xmi:id="103" namespace="GREC Concepts" ID="Allele"/><shared:ExternalReference xmi:id="114" namespace="GREC Concepts" ID="Mutant_Bacteria"/><shared:ExternalReference xmi:id="139" namespace="GREC Concepts" ID="Gene"/><shared:ExternalReference xmi:id="237" namespace="GREC" ID="GRE"/><shared:ExternalReference xmi:id="248" namespace="GREC" ID="Gene_Expression"/><shared:ExternalReference xmi:id="259" namespace="GREC" ID="GRE"/><shared:ExternalReference xmi:id="270" namespace="GREC" ID="GRE"/><shared:ExternalReference xmi:id="281" namespace="GREC" ID="Regulation"/><shared:ExternalReference xmi:id="292" namespace="GREC" ID="GRE"/><shared:ExternalReference xmi:id="303" namespace="GREC" ID="GRE"/><shared:ExternalReference xmi:id="314" namespace="GREC" ID="GRE"/><shared:ExternalReference xmi:id="325" namespace="GREC" ID="Gene_Expression"/><shared:ExternalReference xmi:id="336" namespace="GREC" ID="GRE"/><shared:ExternalReference xmi:id="349" namespace="GREC Concepts" ID="Theme"/><shared:ExternalReference xmi:id="358" namespace="GREC Concepts" ID="Instrument"/><shared:ExternalReference xmi:id="370" namespace="GREC Concepts" ID="Theme"/><shared:ExternalReference xmi:id="383" namespace="GREC Concepts" ID="Theme"/><shared:ExternalReference xmi:id="392" namespace="GREC Concepts" ID="Destination"/><shared:ExternalReference xmi:id="405" namespace="GREC Concepts" ID="Theme"/><shared:ExternalReference xmi:id="414" namespace="GREC Concepts" ID="Instrument"/><shared:ExternalReference xmi:id="426" namespace="GREC Concepts" ID="Theme"/><shared:ExternalReference xmi:id="439" namespace="GREC Concepts" ID="Theme"/><shared:ExternalReference xmi:id="448" namespace="GREC Concepts" ID="Destination"/><shared:ExternalReference xmi:id="461" namespace="GREC Concepts" ID="Agent"/><shared:ExternalReference xmi:id="470" namespace="GREC Concepts" ID="Theme"/><shared:ExternalReference xmi:id="482" namespace="GREC Concepts" ID="Theme"/><shared:ExternalReference xmi:id="494" namespace="GREC Concepts" ID="Theme"/><shared:ExternalReference xmi:id="507" namespace="GREC Concepts" ID="Agent"/><shared:ExternalReference xmi:id="516" namespace="GREC Concepts" ID="Theme"/><semantic:EventAnnotation xmi:id="229" sofa="1" begin="23" end="28" externalReference="237" linkedAnnotationSets="339"/><semantic:EventAnnotation xmi:id="240" sofa="1" begin="29" end="39" externalReference="248" linkedAnnotationSets="361"/><semantic:EventAnnotation xmi:id="251" sofa="1" begin="166" end="171" externalReference="259" linkedAnnotationSets="373"/><semantic:EventAnnotation xmi:id="262" sofa="1" begin="266" end="271" externalReference="270" linkedAnnotationSets="395"/><semantic:EventAnnotation xmi:id="273" sofa="1" begin="276" end="286" externalReference="281" linkedAnnotationSets="417"/><semantic:EventAnnotation xmi:id="284" sofa="1" begin="349" end="361" externalReference="292" linkedAnnotationSets="429"/><semantic:EventAnnotation xmi:id="295" sofa="1" begin="440" end="448" externalReference="303" linkedAnnotationSets="451"/><semantic:EventAnnotation xmi:id="306" sofa="1" begin="456" end="464" externalReference="314" linkedAnnotationSets="473"/><semantic:EventAnnotation xmi:id="317" sofa="1" begin="529" end="539" externalReference="325" linkedAnnotationSets="485"/><semantic:EventAnnotation xmi:id="328" sofa="1" begin="543" end="556" externalReference="336" linkedAnnotationSets="497"/><comparable:IDArray xmi:id="519" array="522" idType="t"/><semantic2:NucleicAcids xmi:id="33" sofa="1" begin="43" end="47" externalReference="41"/><semantic2:NucleicAcids xmi:id="44" sofa="1" begin="149" end="162" externalReference="52"/><semantic2:NucleicAcids xmi:id="55" sofa="1" begin="175" end="179" externalReference="63"/><semantic2:NucleicAcids xmi:id="84" sofa="1" begin="290" end="303" externalReference="92"/><semantic2:NucleicAcids xmi:id="95" sofa="1" begin="365" end="378" externalReference="103"/><semantic2:NucleicAcids xmi:id="131" sofa="1" begin="519" end="528" externalReference="139"/><semantic2:LivingSystems xmi:id="66" sofa="1" begin="234" end="252" externalReference="74"/><semantic2:LivingSystems xmi:id="106" sofa="1" begin="420" end="438" externalReference="114"/><semantic2:EventArgumentSpan xmi:id="26" sofa="1" begin="7" end="19"/><semantic2:EventArgumentSpan xmi:id="77" sofa="1" begin="272" end="303"/><semantic2:EventArgumentSpan xmi:id="117" sofa="1" begin="468" end="495"/><semantic2:EventArgumentSpan xmi:id="124" sofa="1" begin="515" end="539"/><semantic2:EventArgumentSpan xmi:id="142" sofa="1" begin="560" end="575"/><cas:View sofa="1" members="339 346 355 361 367 373 380 389 395 402 411 417 423 429 436 445 451 458 467 473 479 485 491 497 504 513 522 8 21 13 343 352 364 377 386 399 408 420 433 442 455 464 476 488 501 510 41 52 63 74 92 103 114 139 237 248 259 270 281 292 303 314 325 336 349 358 370 383 392 405 414 426 439 448 461 470 482 494 507 516 229 240 251 262 273 284 295 306 317 328 519 33 44 55 84 95 131 66 106 26 77 117 124 142"/></xmi:XMI>