Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:Q9UIJ5 (
Rec
)
58,342
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
A trial was conducted to establish whether there would be any benefit in feeding mammalian pancreatic enzymes to farmed salmon clinically affected by pancreas disease. Pancreatic enzymes were incorporated at a rate of 4 kg/tonne of feed and fed at 0.6 to 0.9 per cent bodyweight/day for 41 days to one
cage
of salmon. The weights, lengths and condition factors were established for the fish before and after the feeding trial and compared with those for an adjacent
cage
of untreated fish. Histopathology and blood amylase and lipase activities were monitored weekly. No significant increases in weight or condition factor, and no reduction in mortalities were recorded. Histopathology confirmed the presence of pancreas disease throughout the trial and there were concurrent skeletal and cardiac myopathies. Blood amylase activities showed no significant change and were considered to be within normal ranges; blood lipase activity remained undetectable.
Vet
Rec
1995 May 13
PMID:Apparent lack of response of salmon affected by pancreas disease to pancreatic enzyme replacement therapy. 767 89
So far as feeding, health and protection from cannibalism are concerned, the welfare needs of laying hens can be well catered for in cages. In other respects, however, cages fail to provide for hens' welfare needs. Deprived of litter, caged hens are prevented from dust bathing and foraging. Without access to a nest site, nesting motivation is frustrated and without a perch, roosting is prevented. Restrictions on movement within a
cage
cause frustration and prevent normal bone maintenance, particularly in the legs and wings. Confinement in a battery
cage
is concluded to cause suffering to laying hens in several different ways.
Vet
Rec
1994 Jun 11
PMID:The welfare problems of laying hens in battery cages. 794 Dec 60
Five catching methods were compared in terms of their effect on the proportion of battery hens which had bones broken when they were removed from battery cages. In addition the effect of tier, lighting intensity during lay and lighting intensity during handling on the prevalence of fractures at catching and on old fractures which occurred during lay was evaluated. Catching and removing hens by one leg from the cages resulted in 11 to 14 per cent of the birds acquiring a broken bone, whereas catching and removing each bird by two legs resulted in 5 per cent of the birds acquiring a freshly broken bone. Removing more than one bird at a time from the
cage
tended to cause more skeletal damage than removing them individually, and incorporating a wooden breast support slide over the feed trough had no effect on the prevalence of broken bones. Catching birds in the top tier of a three-tiered battery unit was more difficult than for the middle or bottom tiers. When the light intensity at catching was the same as that during lay birds were more difficult to catch than when the light intensity was changed, but the effects were insufficient to affect the prevalence of damage to the skeleton.
Vet
Rec
1993 Feb 06
PMID:Effect of catching method and lighting intensity on the prevalence of broken bones and on the ease of handling of end-of-lay hens. 844 51
Pyriproxyfen is a new insect growth regulator with potent activity against developing stages of the cat flea, Ctenocephalides felis. To determine its duration of action after application as a spot-on topical treatment, 20 cats were allocated to two groups. One group acted as untreated controls, and each cat in the other was given a single dose of 1 mg/kg pyriproxyfen. Each cat was infected with fleas at weekly intervals and caged. Eggs were collected and their viability determined as a measure of the effect of the agent on adult fleas. The effect of the transfer of pyriproxyfen from each cat to its immediate surroundings was monitored by observing the development of fertile flea eggs placed on samples of blanket taken from each
cage
. Results from untreated control cats showed that the experimental conditions were favourable for the lifecycle of the flea. Flea reproduction on treated cats was inhibited completely for seven weeks and substantially for at least a further two weeks. Blankets used by cats treated up to two weeks previously prevented flea development entirely and substantial control was still achieved up to four weeks after treatment.
Vet
Rec
1996 Dec 07
PMID:A novel approach to flea control on cats, using pyriproxyfen. 897 67
A novel formulation of cypermethrin was applied as a bath treatment to Atlantic salmon infested with sea lice on a commercial fish farm on the Isle of Skye, Scotland. Twenty 15 m x 15 m cages were treated with cypermethrin at a concentration of 5 micrograms/litre sea water. The numbers of sea lice of all stages were recorded on five fish per
cage
before the treatment and one, seven and 16 days after treatment. Statistically significant reductions in the numbers of chalimus III and IV pre-adults and adults were recorded over the whole period; the average percentage reductions at one and 16 days after treatment were 59 per cent and 90 per cent (chalimus III and IV), 98 per cent and 95 per cent (pre-adults), and 99 per cent (adults), respectively.
Vet
Rec
1997 Feb 15
PMID:Novel cypermethrin formulation for the control of sea lice on salmon (Salmo salar) 906 79
Eighteen healthy beagle dogs of both sexes were each given 0, 2 or 4 mg/kg marbofloxacin intravenously before the subcutaneous implantation of a silicon tissue
cage
. Two millilitres of a suspension containing 1.3 x 10(4) colony forming units (CFU)/ml of Staphylococcus intermedius were then injected into the
cage
15 minutes after the intravenous injection. The dogs were clinically assessed immediately, and then two, four, eight and 24 hours after the challenge. Samples of inflammatory fluid were harvested at the same times in order to count staphylococci and to assay marbofloxacin concentrations. Blood samples were taken in order to assay plasma marbofloxacin levels. The staphylococcal counts were lower in both treated groups than in untreated dogs (P < 0.01). All the clinical criteria were similar in the three groups. The concentration of marbofloxacin was similar in plasma and inflammatory fluid. Both doses were well tolerated and no adverse reactions were observed.
Vet
Rec
1997 Feb 22
PMID:Prevention of surgical infections in dogs with a single intravenous injection of marbofloxacin: an experimental model. 906 72
Flat chests, characterised by a dorsoventral flattening of the rib
cage
, affect 3 to 4 per cent of all Burmese kittens born in the United Kingdom. Similar deformities have been reported in kittens born to taurine-depleted queens. In an investigation of whether there might be a relationship between whole blood taurine levels and the appearance of flat chests it was found that Burmese kittens had significantly (P < 0.05) higher whole blood taurine levels than Burmese queens. In addition, flat-chested Burmese kittens had higher mean (sd) levels (789 [189] mumol/litre) than unaffected Burmese kittens (702 [166] mumol/litre) and non-Burmese kittens (597 [93] mumol/litre), although these differences were not statistically significant. Higher levels of taurine were found in the skeletal muscle and lower levels in the heart muscle of the flat-chested Burmese kittens than in normal non-Burmese kittens.
Vet
Rec
1997 Nov 29
PMID:Investigation of the association between whole blood and tissue taurine levels and the development of thoracic deformities in neonatal Burmese kittens. 942 37
The welfare of seven domestic cats housed singly in a quarantine cattery was studied for six months. Behavioural data were obtained with cameras and by time-lapse video recording, and cortisol to creatinine ratios were measured in urine samples collected from litter trays. It took five weeks for the cats to show evidence of adaptation to their new environment. They spent most of the first two weeks concealed in a house on the floor of their
cage
. As they adapted, they spent less time hiding and more time higher in the
cage
. The cats were inactive for approximately 90 per cent of the time observed, and they received little human contact. Compared with the first day, the cats' cortisol to creatinine ratios were significantly lower from their second month in quarantine.
Vet
Rec
1998 Jul 11
PMID:Welfare of cats in a quarantine cattery. 969 49
In a clinical trial involving 123 cats and 88 dogs, the efficacy of tablets containing nitenpyram against natural flea infestations was investigated. The animals were selected from the routine cases of nine veterinary clinics in the UK and 143 were treated with the tablets and 68 control animals were treated with placebo tablets. Each animal was maintained in an individual
cage
. The time when the first fleas fell off each animal was recorded between 30 minutes and five hours after treatment, and six hours after treatment the numbers of live, moribund or dead fleas on each animal were determined, and the flea survival rate was calculated. The drug's efficacy was assessed by comparing the mean survival rates of fleas on the treated and control animals. Fleas started to fall from the animals 30 minutes after treatment and two hours after treatment some fleas had detached from 81 per cent of the treated animals. After six hours the efficacy of the drug reached 96.7 per cent on dogs and 95.2 per cent on cats, and 85.9 per cent of the fleas were found off the treated animals, compared with 1.8 per cent in the controls. No adverse drug reactions were recorded during the trial.
Vet
Rec
2000 Dec 16
PMID:Efficacy of nitenpyram as a systemic flea adulticide in dogs and cats. 1114 Sep 29
Faecal, dust and other environmental samples were collected from the floors, droppings belts, egg-collection systems and other areas of 14
cage
-layer flocks, 10 barn egg production flocks and seven free-range flocks, and cultured for Salmonella species. The distribution of the organism varied with its prevalence and with the vaccination status of the birds. No one sample type was found to be suitable for identifying all contaminated houses. Salmonella was also frequently found on egg-packing equipment and in samples from rodents and wild birds.
Vet
Rec
2001 Dec 08
PMID:Environmental contamination and detection of Salmonella enterica serovar enteritidis in laying flocks. 1178 81
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