Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:Q9UIJ5 (
Rec
)
58,342
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
In the present study, we established transgenic mice overexpressing
Del1
, a ligand of integrins, to examine the effect of overexpression of
Del1
on vascular morphogenesis. In the wild-type mouse, mesenteric vessels are shaped like rakes consisting of a long stalk and short branches at the periphery. In contrast, those in transgenic mice showed typical dendritic architecture consisting of a few large primary branches with smaller spreading branches. The phenotype of mice overexpressing
Del1
suggests the existence of a tissue-specific mechanism for branching morphogenesis in the mesentery.
Anat
Rec
A Discov Mol Cell Evol Biol 2005 Dec
PMID:Overexpression of the Del1 gene causes dendritic branching in the mouse mesentery. 1630 30
