Gene/Protein Disease Symptom Drug Enzyme Compound
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Small fragments of kidney tissue were grafted into the right lung (Xenopus laevis) and the left lung was subsequently removed. This stimulated compensatory hyperplasia (increased mitotic rate) in alveolar tissue of the right lung and in the kidney graft. This suggests that the stimulus to compensatory hyperplasia is location-specific rather than tissue- or organ-specific. After implantation into the lung the kidney grafts are revascularized by the surrounding pulmonary supply. Damage or functional impairment of an organ usually produces a localized increase in the rate of blood flow and we therefore propose that this may lead to an increased rate of cell division in one of two ways: by permitting an increased functional capacity in the tissue concerned, or by causing a more rapid local clearance of mitotic control factors.
Anat Rec 1977 Feb
PMID:Stimulation of cell division in ectopic kidney grafts following unilateral removal of the lung. 32 42

A parasitic dermatitis, caused by a nematode infestation of the epidermis, was diagnosed in 11 captive African clawed frogs (Xenopus laevis) by a histological examination of the skin. Eight of the animals died or were euthanased before effective treatment with levamisole was administered, and one frog died after being treated. Secondary infection with opportunistic pathogens may have been involved in the progression of the disease.
Vet Rec 1996 Jun 29
PMID:Diagnosis and treatment of a parasitic dermatitis in a laboratory colony of African clawed frogs (Xenopus laevis). 881 58