Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:Q9UIJ5 (
Rec
)
58,342
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The genotoxicity of beryllium, gallium and antimony compounds was studied with the
rec
, Salmonella mutagenicity and SCE assays. In the
rec
assay, all the salts of the metals,
BeCl2
, Be(NO3)2, GaCl3, Ga(NO3)3, SbCl3, SbCl5, and an oxide, Sb2O3, had DNA-damaging activity. None of the compounds was mutagenic to Salmonella. In the SCE assays using V79 cells, 2 antimony(III) compounds, SbCl3 and Sb2O3, and 2 beryllium compounds,
BeCl2
and Be(NO3)2, induced SCEs significantly. Sb2O3, slightly soluble in water, was positive in both the
rec
assay and the SCE assay at very low doses.
...
PMID:Genotoxicity of beryllium, gallium and antimony in short-term assays. 172 93
