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The study of cattle respiratory diseases during the last decade show that several observations made in the late 1960s are still relevant today. Many of these diseases are shared with other countries in Europe, but the developments discussed will be examined with the respiratory disease problems that occur in Britain in mind. The new information is dealth with as it applies to (i) structure, function and immunology of the lungs (ii) diseases of calves indoors (iii) diseases of young animals grazing, (iv) diseases of adult animals indoors and (v) diseases of adult animals grazing.
Vet Rec 1977 Sep 24
PMID:Recent advances in respiratory conditions in cattle. 14 49


Vet Rec 1975 Sep 06
PMID:Antibodies to parainfluenza 3 virus in cattle, sheep and goats from northern Nigeria. 16 21


Vet Rec 1976 Sep 11
PMID:Atypical fowl pox in chickens. 18 80

The occurrence of diarrhoea in calves was monitored during the first three weeks of life. Calves fed amounts of colostrum sufficient to produce serum Ig levels in excess of 30 mg per ml did not develop diarrhoea, whereas calves fed less colostrum did. Rotaviruses and mycoplasma-like particles were observed in the faeces of calves with and without diarrhoea. The epidemiology of rotavirus infection in calves is discussed.
Vet Rec 1976 Sep 18
PMID:Studies on rotavirus infection and diarrhoea in young calves. 18 78


Vet Rec 1976 Sep 25
PMID:Infectious bursal disease of chickens and vaccination. 18 79

Large unilateral tumours involving the mandible in two calves were composed of melanin-containing cells and small lymphocyte-like cells in a cellular fibrous stroma. These neoplasms resembled the melanotic neuro-ectodermal tumour of infancy.
Vet Rec 1977 Sep 24
PMID:Melanotic neuro-ectodermal tumour of infancy (melanotic progonoma) in two calves. 19 80

Enzootic bovine leucosis is associated with infection by bovine leucosis virus. The incubation period is measured in years and a minority of infected animals develop clinical signs. The disease is widespread in Europe and elsewhere and can cause significant economic loss. The epidemiology is incompletely understood and findings from one cattle production system may not be directly applicable to another. Major control programmes exist in Denmark and West Germany and control schemes are being developed elsewhere. Eradication of enzootic bovine leucosis has been established as a goal in the EEC and research is revealing the ways in which this goal may be attained. To be effective, control and epidemiological monitoring must be interactive. Recently introduced serological tests, of improved sensitivity, provide a valuable tool.
Vet Rec 1978 Sep 02
PMID:Enzootic bovine leucosis. 21 58

The effect of field feline viral rhinotracheitis (FVR) virus challenge on cats previously vaccinated with a combined FVR/feline calicivirus intramuscular vaccine was studied in relation to the development of an FVR carrier state. There was no virus shedding of either of the two vaccine viruses following vaccination. Treatment with corticosteroid 60 days after vaccination and before challenge with FVR virus did not induce virus re-excretion in vaccinates or controls; neither did similar treatment induce shedding 63 days after challenge of both vaccinates and controls with virulent field virus. After a further 55 days however, FVR virus shedding was elicited in one of four previously vaccinated and challenged cats compared with two of four unvaccinated and challenged controls. Two sentinel cats remained virologically and serologically free of FVR throughout. The vaccine was shown to be effective in controlling the disease; 12 weeks after initial vaccination no clinical signs were seen in three of four cats following intranasal challenge with 10(5)CCID50 of virulent field FVR virus, and a mild transient unilateral ocular and nasal discharge was seen in the remaining cat for one day only. Severe clinical signs of approximately 10 days' duration were seen in all four unvaccinated challenged controls. The virological and serological responses of the cats were also recorded.
Vet Rec 1978 Sep 02
PMID:Interaction of a combined feline viral rhinotracheitis-feline calicivirus vaccine and the FVR carrier state. 21 59

The objective of this study was to determine the effects of chronic dexamethasone (DEX) administration on hepatic ultrastructure and to correlate these changes with plasma lipoprotein levels. Electron microscopic studies were made of hepatocytes from male rats killed 1, 3 and 5 days after DEX (2 mg, twice per day) administration. Three days after treatment plasma lipoprotein levels were highest and hepatocytes contained regions of the cytosome rich in elements of the smooth endoplasmic reticulum (SER). Osmiophilic particles were present in the tubules and vesicles of the SER, in the saccules and vacuoles of the Golgi complex, in secretory vesicles near the cell surface and in the space of Disse. DEX treatments also caused hepatocytes to accumulate tightly packed masses of beta-particles of glycogen in some regions of the cell while other areas displayed dispersed glycogen particles that were associated with the SER. These observations are consistent with the hypothesis that glucocorticoids 1. cause an elevation of plasma lipoprotein levels by increasing hepatic synthesis and secretion of VLDL, which involves the sequential participation of the ER, the Golgi complex and exocytosis of VLDL-containing vacuoles into the space of Disse, and 2. produce a change in the nature of the association of glycogen particles with the SER membranes in response to the physiological state of the animal.
Anat Rec 1978 Sep
PMID:Alterations in hepatic fine structure after chronic exposure of rats to dexamethasone. 21 64


Vet Rec 1978 Sep 16
PMID:Woodrige Memorial Lecture. The veterinary profession and an intensive poultry industry. 21 71


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