Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UNIPROT:Q9UIJ5 (Rec)
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A midventrally located fusiform sebaceous gland is found in the northern grasshopper mouse Onychomys leucogaster. Microscopically, the gland consists of numerous multilobular units. Copious secretory material collects in the central duct of each unit and is extruded to the outside. The gland is larger in the male than in the female. Castration causes an involution of the gland in both sexes. Testosterone propionate (1.0 mg/0.1 cc olive oil, subcutaneously every other day for 4 weeks) restores the gland to full activity in castrates of both sexes. Estradiol benzoate (0.1 mg/0.1 cc olive oil, subcutaneously every other day for 4 weeks) has no effect on the midventral gland of ovariectomized females. A long photoperiod (18 L/6 D) leads to the development of testes, ovaries, and uteri that are significantly heavier than those of animals from a short photoperiod (6 L/18 D) regime. Midventral glands in animals of both sexes from the long photoperiod are larger and more active than glands from animals from the short photoperiod. The secretions of the midventral gland of Onychomys are probably used for communications such as territorial marking, advertisement of gonadal status, or pup identification.
Anat Rec 1985 Mar
PMID:Effects of hormones and gonadal status on the midventral gland of the grasshopper mouse Onychomys leucogaster. 388 90

The effects of oestradiol benzoate or of experimentally induced infection on the absorption of sodium benzylpenicillin from the uterus were investigated in three groups of clinically normal, non-pregnant, Friesian cows. All were at day 12 following the day of oestrus. Oestradiol benzoate in oil was administered either into the uterus or intramuscularly one hour before the infusion of 22,000 iu/kg of sodium benzylpenicillin. The dose of oestradiol benzoate was 10 mg, apart from one cow in each group which received 25 mg. Inflammation was induced by infusing a suspension of Corynebacterium pyogenes in Ringer's solution into the uterus, 11 to 18 hours before penicillin infusion. The degree of absorption of penicillin was greater in all three groups than that previously determined in cows given penicillin alone at the same stage of the cycle. The results indicate that factors which might affect blood flow to the uterus may also influence the absorption of sodium benzylpenicillin from the uterus.
Vet Rec 1982 Jan 30
PMID:Effects of exogenous oestrogen and experimentally induced endometritis on absorption of sodium benzylpenicillin from the cow's uterus. 718 96