Gene/Protein Disease Symptom Drug Enzyme Compound
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The chronology of the discoveries along the pathway of vitamin B12 biosynthesis is reviewed from a personal perspective, including discussion of the most recent finding that two pathways to B12 exist--one aerobic and one anaerobic--which differ mainly in the ring contraction mechanisms which convert porphyrin to corrin.
Chem Rec 2001
PMID:Reflections on the discovery of nature's pathways to vitamin B12. 1189 20