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Query: UNIPROT:Q9UIJ5 (
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The
octane
plasmid (OCT) in Pseudomonas putida strains has been shown to be transferred at low frequency. However, bacteria which had newly received this plasmid showed a transient increase in donor ability. Using Octane+ P. putida as the donor, the transfer of most chromosomal markers was shown to be independent of OCT transfer, whereas the mobilization of the octanoate catabolism genes (octanoic and acetate) was dependent on OCT plasmid transfer. The presence of a fertility factor termed FPo has been postulated to explain these results. Strains carrying only this fertility factor have been obtained from strains carrying both OCT and FPo plasmids. Strains in which the OCT plasmid was transferred at high frequencies have also been isolated, and chromosome mobilization by OCT and FPo has been compared. A different gradient of transmission by OCT and FPo has been observed. It has also been shown that chromosome transfer by OCT was dependent on the bacterial recombination system, whereas the chromosome transfer by FPo was unaffected by the presence of a
rec
mutation in the donor strain.
...
PMID:Fertility factors in Pseudomonas putida: selection and properties of high-frequency transfer and chromosome donors. 76 14
Atisane-type diterpenoids are the principal constituent of tetracyclic C
20
-diterpenoids, widely isolated from the plant kingdom with varying degrees of structural complexity and pharmacological activity. The tetracarbocyclic system with the unique bicyclo[2.2.2]
octane
skeleton of this natural product family has generated interest within the synthetic community. Divergent total synthesis is an effective tactic to synthesize several atisane-type diterpenoids using structural interconversion from a common intermediate. This account summarizes the divergent total synthesis of atisane-type diterpenoids.
Chem
Rec
2017 06
PMID:Divergent Total Synthesis of Atisane-Type Diterpenoids. 2788 41
