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The clinical and radiological features of 30 cases of anterior mediastinal lymphosarcoma in the cat are described; they represented 48 per cent of all cases of lymphosarcoma recorded at the University of Bristol Veterinary School between 1972 and 1977. The condition principally affected young cats and there was a predisposition in oriental breeds. Dyspnoea and regurgitation were the two most common major presenting signs. Diagnosis was made in most cases on the basis of radiological examination, but in some cytological examination of the thoracic fluid was necessary for confirmation.
Vet Rec 1979 Apr 07
PMID:Clinical and radiological features of anterior mediastinal lymphosarcoma in the cat: a reveiw of 30 cases. 58 89

Regurgitation of blood through the left atrioventricular valve owing to the rupture of one of the chordae tendineae of the valve was diagnosed in a horse with sudden-onset respiratory distress and a holosystolic cardiac murmur. Severe regurgitation was confirmed with Doppler echocardiography and prolapse of part of the valve leaflet was identified with B-mode ultrasonography. The rupture of one of the chordae tendineae of a right accessory cusp of the left atrioventricular valve was confirmed post mortem. Bronchiolitis, multifocal haemorrhages and haemorrhagic fibrous plaques were found in the pleura of the dorsocaudal segments of the lungs.
Vet Rec 1990 Oct 13
PMID:Confirmation by Doppler echocardiography of valvular regurgitation in a horse with a ruptured chorda tendinea of the mitral valve. 226 Feb 52

It was shown that the effects of halothane anaesthesia in the dromedary are similar to those of large domestic ruminants. As a general rule the equipment and techniques used for adult cattle may also be used in the dromedary. Endotracheal intubation may be more difficult in camels because of their narrow oral cavities. Involuntary regurgitation is a particular hazard in dromedaries and every effort should be made to avoid this potentially life threatening complication.
Vet Rec
PMID:Halothane anaesthesia in the dromedary camel. 381 Nov 82

A young kitten was presented with regurgitation of food at weaning. Episodes of respiratory distress and cyanosis were also present. The cause of food regurgitation was a perioesophageal vascular ring caused by left descending aorta and a right ligamentum arteriosum. This type of vascular ring has not previously been described. There was also anomalous development of the right subclavian artery and a large ventricular septal defect. The respiratory distress and cyanosis was most probably caused by a combination of tracheal compression by the vascular ring and a polycythaemia associated with the ventricular septal defect. Surgical correction was not attempted.
Vet Rec 1984 Apr 07
PMID:Unusual vascular ring in a cat: left aortic arch with right ligamentum arteriosum. 671 87

A total of 147 pigs were observed from weaning to marketing to see what effect ulceration of the stomach had on the growth rate. Nine pigs showed ill-thrift and had severe gastric ulcers. These animals ate slowly with frequent regurgitation and at post mortem examination showed constriction of the cardia, caused by cicatrisations of the pars oesophagea, with hypertrophy of the caudal part of the oesophagus. Growth rates of these animals were significantly lower than those of normal pigs.
Vet Rec 1980 Jan 19
PMID:Effects of gastric ulceration on growth rate of intensively reared pigs. 736 28

The diagnosis of dysphagia in the dog requires an evaluation of a variety of signs that can be caused not only by a 'swallowing disorder' but also by several other pathological conditions. Most owners mention coughing, vomiting, regurgitation and nasal discharge, and the clinician must decide whether these signs are related to dysphagia. In this study a standardised questionnaire for the diagnosis and localisation of dysphagia was evaluated for its accuracy by comparing the results with contrast videofluorography as the definitive standard. The purpose of the study was to optimise the selection of dogs for more expensive diagnostic procedures such as videofluorography and electromyography. In a group of 69 dogs with 'swallowing problems' the questionnaire had a sensitivity of 0.97 and a positive predictive value of 0.94 for dysphagia in general. The questionnaire was also useful for the exclusion of oral phase dysphagia, with a specificity of 0.70 and a negative predictive value of 0.97. Most dogs with pharyngeal phase dysphagia could be detected by using the questionnaire (sensitivity 0.91). The questionnaire was not of specific value for the detection or exclusion of oesophageal phase dysphagia, for which it had a sensitivity of 0.69, a specificity of 0.57 and predictive values for positive and negative tests of 0.79 and 0.44, respectively.
Vet Rec 1993 Feb 27
PMID:Evaluation of a standardised questionnaire for the detection of dysphagia in 69 dogs. 845 12

Lower oesophageal pH was monitored in 240 anaesthetised dogs. The incidence of gastro-oesophageal reflux was 16.3 per cent and most of the reflux episodes occurred shortly after the induction of anaesthesia. The refluxate was nearly always acid (pH < 4.0), but in 10.3 per cent of the cases it was alkaline (pH > 7.5); gastric contents of pH below 2.5 were refluxed on 19 occasions (7.9 per cent). Regurgitation occurred in only one dog. Prolonging preoperative fasting was associated with an increased incidence of reflux and increased gastric acidity. Premedication with diazepam was associated with fewer reflux episodes than premedication with atropine and propionylpromazine.
Vet Rec 1995 Nov 04
PMID:Gastro-oesophageal reflux during anaesthesia in the dog: the effect of preoperative fasting and premedication. 857 60

Lower oesophageal pH was monitored in 270 dogs under anaesthesia. There were 47 episodes of gastro-oesophageal reflux (17.4 per cent), most of which occurred shortly after the induction of anaesthesia. The refluxate was usually acid (pH < 4.0), but in four of the episodes (8.5 per cent) it was alkaline (pH > 7.5). Gastric contents with a pH below 2.5 were refluxed on 27 occasions (10 per cent) for an average period of about 44 minutes. Regurgitation occurred in two of the dogs. Increased age seemed to be associated with an increased incidence of reflux and an increased gastric acidity. Body position (sternal, dorsal and left or right lateral) and the tilt of the body during surgery (horizontal or tilted to an 8 degrees head-up or head-down position) had no influence on the incidence of gastro-oesophageal reflux. Dogs undergoing intra-abdominal surgery had significantly more reflux episodes than dogs undergoing non-abdominal surgery.
Vet Rec 1995 Nov 11
PMID:Gastro-oesophageal reflux during anaesthesia in the dog: the effect of age, positioning and type of surgical procedure. 858 77

This study investigated the epidemiology and prognostic significance of mitral valve prolapse, detected by ultrasonography, in 153 cavalier King Charles spaniels which were screened consecutively during a period of one year. Seventy-five of the dogs, which had either no murmur or a grade I murmur on screening, were reexamined three years later. The screening revealed that 82 per cent of the dogs aged one to three years and 97 per cent of the dogs over three years had various degrees of mitral valve prolapse. The presence and severity of the condition were independent of gender but correlated positively with age and negatively with bodyweight. The degree of mitral valve prolapse at screening correlated with the regurgitation status (murmur intensity and size of the regurgitant jets) at re-examination and with the percentage increase in the left ventricular end diastolic diameter over the three-year period. The presence of a grade I murmur was not a useful prognostic indicator.
Vet Rec 1999 Mar 20
PMID:Echocardiographic mitral valve prolapse in cavalier King Charles spaniels: epidemiology and prognostic significance for regurgitation. 1021 5

The general health of a German shepherd dog had deteriorated slightly when it was found after being loose for one hour. After 10 hours of observation, the dog showed signs of pain for the first time and signs of poisoning, such as tenseness of muscles, slight opisthotonus, regurgitation, salivation, mydriasis, dyspnoea and cyanosis, were observed; it died 15 minutes after showing the first clinical signs but it had no seizures or tetanic spasms at any time. A postmortem examination did not reveal any pathological changes. A screening test for alkaloids was positive for strychnine (strychnidin-10-one). The presence of strychnine was confirmed and its concentration was determined by gas chromatography/mass spectrometry in urine (728.5 ng/ml) and in the stomach contents (44.6m microg/g). No strychnine was detected in the dog's serum, but traces of brucine (2,3-dimethoxystrychnidin-10-one), the dimethoxy derivative of strychnine, were detected. This case was compared with other strychnine poisonings recorded in the authors' laboratory over the previous six years, taking into account the species, type of samples, the clinical signs and their duration, the postmortem findings, and the concentrations of strychnine. This was the only case to show such an atypical time course of clinical signs.
Vet Rec 2002 Jul 06
PMID:Atypical time course of clinical signs in a dog poisoned by strychnine. 1213 20


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