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In four outbreaks of indoor calf pneumonia, dyspnoea was a prominent clinical finding. At necropsy it was associated with pneumonia involving the cranial lobes of the lung and severe pulmonary emphysema. Histological examination of lung tissue revealed bronchiolitis and alveolitis with alveolar epithelial cell hyperplasia and multinucleate syncytium formation. Intraalveolar haemorrhage, intra-alveolar oedema and hyaline membrane formation were also noted. In all cases parainfluenza type 3 (PI3) virus was isolated from the lungs. In each of the four outbreaks there was evidence of PI3 virus and respiratory syncitial virus (RSV) infection.
Vet Rec 1979 Jan 20
PMID:Observations on outbreaks of respiratory disease in calves associated with parainfluenza type 3 virus and respiratory syncytial virus infection. 21 84

The clinical and radiological features of 30 cases of anterior mediastinal lymphosarcoma in the cat are described; they represented 48 per cent of all cases of lymphosarcoma recorded at the University of Bristol Veterinary School between 1972 and 1977. The condition principally affected young cats and there was a predisposition in oriental breeds. Dyspnoea and regurgitation were the two most common major presenting signs. Diagnosis was made in most cases on the basis of radiological examination, but in some cytological examination of the thoracic fluid was necessary for confirmation.
Vet Rec 1979 Apr 07
PMID:Clinical and radiological features of anterior mediastinal lymphosarcoma in the cat: a reveiw of 30 cases. 58 89

A six-months-old heifer died within two days of showing signs of anaemia and dyspnoea. The death was attributed to autoimmune haemolytic anaemia (AHA) because of auto-agglutination which increased on Coomb's testing and the presence of antibovine IgG on the erythrocyte surfaces.
Vet Rec 1978 Aug 19
PMID:Bovine auto-immune haemolytic anaemia. 69 64

An acute respiratory distress syndrome in 10 adult dogs was usually preceded by vomiting, anorexia and lethargy followed, after a short interval, by dyspnoea. The dyspnoea became increasingly severe, despite oxygen therapy, and cyanotic respiratory failure ensued. All 10 dogs died or were killed after illnesses lasting between one and eight days. Necropsies revealed pulmonary congestion, oedema, collapse and haemorrhage with loss of alveolar epithelial cells. Early alveolar fibrosis was also found. Paraquat was identified in post mortem samples from four of the 10 dogs.
Vet Rec 1977 Apr 02
PMID:Acute respiratory distress in the dog associated with paraquat poisoning. 86 Mar 82

Broken wind is a syndrome characterised by chronic bronchitis and alveolar emphysema. Clinical signs include nasal catarrh, persistent coughing, dyspnoea and poor exercise tolerance. In racehorses, lung haemorrhages may result in epistaxis. Broken wind is a disease of domestication ascribed to pollution of the stable air with fungal spores from hay and straw. Treatment and prevention are based on the provision of fresh air and, if housing is unavoidable, the adoption of a permanent regime of dust-free stable management. If an early diagnosis is made and appropriate treatment instituted, the prognosis is considered to be reasonably good. The disease exemplifies the validity of the Royal Veterinary College motto Venienti occurrite morbo (treat the disease at its first appearance).
Vet Rec 1976 Dec 04
PMID:Chronic bronchitis and alveolar emphysema in the horse. 99 95

Maedi-visna virus infection in a flock of sheep in Scotland was associated with respiratory disease, neurological disease, mastitis and lameness. The major clinical signs were dyspnoea (particularly on exercise), progressive fore- and hindlimb ataxia and balance defects, mammary induration and multilimb lameness, occasionally with enlarged carpal joints. Pathological examinations revealed lesions in the lungs, central nervous system, mammary glands and joints which were consistent with those induced by maedi-visna virus. The was no clinical or pathological evidence of concurrent sheep pulmonary adenomatosis, and pulmonary bacterial infections, when they occurred, were superimposed on the lesions due to maedi-visna virus.
Vet Rec 1992 Nov 14
PMID:Clinicopathological investigation of primary, uncomplicated maedi-visna virus infection. 838 91

The duration of immunity as measured by virological, serological and clinical responses following infection with influenza A/equine/Newmarket/79 (H3N8) was assessed in repeated challenge experiments in which ponies were infected by exposure to aerosols of infectious virus. Previous infection stimulated complete clinical protection which persisted for at least 32 weeks as demonstrated by the absence of febrile responses and coughing in two groups of ponies infected 16 weeks or 32 weeks after the first infection. Partial clinical protection persisted for over a year as demonstrated by the absence of coughing and a reduction in the number of febrile responses in a group of ponies infected 62 weeks after their first infection. These results contrasted with those observed in immunologically naive control ponies which developed pyrexia, dyspnoea and nasal discharge and coughing. The kinetics of virus specific antibody production in primary and secondary infections with equine influenza were studied by the single radial haemolysis test and a radioisotopic antiglobulin binding assay which measured virus specific IgGab antibody isotype. Antibody to the haemagglutinin, as measured by the single radial haemolysis test, declined rapidly after primary infection whereas the IgGab responses to whole virus antigens persisted for longer. The single radial haemolysis test was therefore particularly useful for the detection of antibody responses in multiple infections or exposures to influenza antigens. The radioisotopic antiglobulin binding assay was more sensitive for identifying infections which had occurred more than six months previously, as evidenced by anamnestic IgGab responses in ponies with low levels of antibody before rechallenge.
Vet Rec 1988 Feb 06
PMID:Duration of circulating antibody and immunity following infection with equine influenza virus. 283 50

An obstructive, upper respiratory tract disease characterised by severe dyspnoea and deaths has been recognised in Texel sheep. It is caused by chronic suppuration within the arytenoid cartilages of the larynx resulting in swelling and occlusion of the lumen. The clinical and pathological features of the disease are described and its possible cause and treatment are discussed.
Vet Rec 1987 Jul 25
PMID:Laryngeal chondritis in Texel sheep. 362 94

Fifteen newborn Poll Hereford calves from five farms died over a three-and-a-half year period. From birth all calves had a tight, curly hair coat which was not observed on any other calves on these properties. All calves with this phenotype died before reaching six months of age. Seven of the 15 calves were noticed to have exercise intolerance, hyperpnoea and dyspnoea for one to seven days before death. The incidence of additional features of the curly hair coat phenotype is also described. Post mortem examinations conducted on the calves revealed focal, diffuse and pale fibrous streaking of the entire myocardium and vascular congestion of the livers, spleens and lungs. A primary cardiomyopathy was diagnosed on the basis of the clinical and pathological findings. Analysis of the pedigrees of seven affected calves from one farm demonstrated a common ancestor for all sires and dams of affected calves and suggested a simple autosomal recessive mode of inheritance of the syndrome as a reasonable hypothesis for future experimental testing.
Vet Rec 1985 Sep 21
PMID:Cardiomyopathy associated with a curly hair coat in Poll Hereford calves in Australia. 406 May 39

A 16-day infection of Dictyocaulus viviparus in two groups of calves was treated with levamisole and fenbendazole respectively. Five days afterwards the calves were reinfected with 4000 larvae and necropsied 21 days later. Although the lungworm burdens of the two groups of calves were reduced by about 70 per cent compared to a control group the clinical signs of dyspnoea, tachypnoea and coughing were indistinguishable from a primary infection. This was due to pulmonary emphysema, oedema and an acute epithelialising pneumonia apparently associated with the death and disintegration of lungworms in situ, the result of an incompletely developed immune response. The results are compared with those obtained with the lungworm vaccine. It was concluded that the outcome of any system of "control" which depends on drug therapy and reinfection is unpredictable and that vaccination offers the only effective method of prophylaxis.
Vet Rec 1981 Feb 28
PMID:Control of parasitic bronchitis in calves: vaccination or treatment? 645 78


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