Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:Q9UIJ5 (Rec)
 58,342 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A study of diarrhoea in unweaned piglets was carried out in nine herds, with special reference to the enteropathogenic agents which could be demonstrated. Coccidial (Isospora suis) and rotaviral infections were both identified, either singly or in combination. More extensive studies of I suis infection were undertaken in two of the herds and it was found that diarrhoea occurred most commonly in five- to 14-day-old piglets. Piglets with I suis infection were not necessarily diarrhoeic but grew poorly compared to uninfected piglets. I suis infection in litters correlated with oocyst excretion in sows. In herds with I suis infection, amprolium and monensin were used in the sow ration to achieve control, and in one herd oral dosing of piglets with amprolium in the first three or four days of life was carried out.
Vet Rec 1982 Jan 02
PMID:Field study of coccidial and rotaviral diarrhoea in unweaned piglets. 627 96

A case of chronic intermittent diarrhoea in a dog is reported. Large numbers of Clostridium perfringens type A were recovered from the faeces. A toxin neutralised by C perfringens type A antitoxin was demonstrated in the same samples. No clear predisposing factors contributing to the condition could be determined. The dog recovered following a 10 day course of metronidazole at 20 mg/kg/day per os and a change to a bland diet.
Vet Rec 1983 Apr 09
PMID:Recurrent diarrhoea in a dog associated with Clostridium perfringens type A. 630 87

A longitudinal survey of rotavirus infection in heifer calves was carried out on a closed Friesian dairy herd over two successive calving seasons. Rotavirus was detected by electron microscopy in the faeces of 45 of 57 (79 per cent) calves examined. On average the virus was first detected at 6.1 days of age. Clinically the disease associated with rotavirus infection was of mild to moderate severity. Only one infected calf required intravenous fluid therapy. Diarrhoea or excretion of abnormal faeces was associated with rotavirus infection in 58 per cent of infected calves, while in the remaining 42 per cent infection was subclinical. The cycle of rotavirus infection was broken by thorough cleansing and disinfection of the calf house.
Vet Rec 1983 Oct 08
PMID:Longitudinal survey of rotavirus infection in calves. 631 19

The introduction of a heifer which was persistently infected with bovine virus diarrhoea-mucosal disease virus into groups of pregnant cattle resulted in abortion, neonatal death, persistent infection and, subsequently, mucosal disease in the surviving progeny. Cattle affected with mucosal disease were invariably seronegative at the time of investigation and subsequent cases occurred only in calves previously identified as seronegative and persistently infected. The detection of virus antigen by immunofluorescent staining of cells obtained from the nasopharynx was shown to be an efficient and rapid method for identifying persistently infected cattle, correlating perfectly with virus isolation.
Vet Rec 1984 Mar 31
PMID:Mucosal disease of cattle: a late sequel to fetal infection. 632 25

Enzyme-linked immunosorbent assay (ELISA) was compared with electron microscopy in the examination of faeces from experimental calves and showed 100 per cent agreement in the detection of 19 bovine coronavirus and 15 bovine rotavirus electron microscope positive samples. In a limited field survey of calf diarrhoea 75 selected faeces were examined independently by ELISA and electron microscopy and the agreement between the two tests was 95 per cent for coronavirus and 84 per cent for rotavirus. A further comparison was made with 74 samples submitted for routine diagnosis and this yielded agreements of 82 per cent (coronavirus) and 89 per cent (rotavirus). Factors contributing to discrepant results were examined and the relative advantages and disadvantages of the two tests for routine detection of these enteric viruses are discussed.
Vet Rec 1984 Apr 21
PMID:Evaluation of ELISA and electron microscopy for the detection of coronavirus and rotavirus in bovine faeces. 632 30

Campylobacter jejuni was recovered from 59 of 505 (11.7 per cent) dogs with diarrhoea as compared with only two of 122 (1.6 per cent) dogs without diarrhoea. However, there was no significant difference between campylobacter isolations from 142 cats with and without diarrhoea. C jejuni infections were commonly associated with chronic diarrhoea in both species and appropriate therapy abolished clinical signs and excretion of the organism in faeces in most cases. C jejuni may be responsible for some forms of enteritis in dogs and cats and is a zoonosis in which the companion animal may be the vector.
Vet Rec 1983 Oct 15
PMID:Association of Campylobacter jejuni with enteritis in dogs and cats. 664 62

Pure cultures of an isolate of Campylobacter fetus subspecies intestinalis obtained from the congested small intestinal mucosa of a two-week-old calf were used to infect three milk-fed calves and three ruminating calves in two separate controlled experiments. Inoculated animals all developed clinical signs which included fever (to 40 degrees C) and diarrhoea with excess clear mucus containing occasional spots of blood. C fetus subspecies intestinalis was isolated from the faeces of all infected animals in the two experiments but not from those of the five control animals. Changes in the enteric tract were most marked in the ileum which was thickened and mildly inflamed with accumulations of lymphoid cells and crypts filled with inflammatory cells in all six infected animals. The mesenteric lymph nodes were pale and enlarged. C fetus subspecies intestinalis was recovered from the jejunum, ileum, caecum and colon of the infected animals and less frequently from the abomasum, mesenteric lymph nodes, liver and gall bladder. It was never isolated from the control animals. Antibody to the inocular strain of C fetus subspecies intestinalis was demonstrated, at titres of at least 1 in 320, in the serum of all inoculated animals and was absent from all the control sera. The findings were considered to indicate that C fetus subspecies intestinalis caused the syndrome described above and that the syndrome produced differed only in minor details from that produced in calves by infection with C jejuni.
Vet Rec 1983 Jan 15
PMID:Production of enteritis in calves by the oral inoculation of pure cultures of Campylobacter fetus subspecies intestinalis. 683 83

Treatment of diarrhoeic calves by oral administration of a glucose-glycine-electrolyte solution (GGES) was compared with milk deprivation (water given instead) and with no treatment (milk-fed controls). The diarrhoea followed challenge with enteropathogenic Escherichia coli. The GGES group showed a significantly lower mortality (5 per cent) in comparison with the controls (37 per cent). The milk-deprived group had a slightly lower mortality (30 per cent) in comparison with the controls. The milk deprived group showed a significantly prolonged duration of diarrhoea in survivors compared with the control group, while the GGES group did not differ significantly from the controls. Calves arriving on farms were allocated randomly to either GGES or to an alternative control treatment (usually partial milk deprivation). The incidence of diarrhoea during the subsequent two weeks was significantly less in the GGES group. Clotting of milk by rennet was impaired by addition with either water or an alkaline electrolyte solution but was enhanced by dilution with GGES.
Vet Rec 1980 Dec 13
PMID:Comparison between milk deprivation and oral rehydration with a glucose-glycine-electrolyte formulation in diarrhoeic and transported calves. 700 33

In 138 mongrel dogs given renal transplants, 10 developed postoperative intussusceptions. The sites were jejunojejunal (seven), ileo-ileal (two) and ileocolic (one). In 30 puppies given intrasplenic autografts of dispersed pancreatic fragments after total pancreatectomy, five developed jejunojejunal intussusceptions. Presenting signs included vomiting, failure to eat, periodic attacks of pain, straining with the passage of bloodstained mucous, dehydration, weight loss, abdominal wall rigidity and an abdominal mass. The majority of dogs presented within the first seven days following transplantation, occasionally as late as the third week. Early operative intervention was essential to save the dogs and at laparotomy eight of nine intussusceptions were successfully reduced manually; one small bowel resection was performed for irreducibility. Recurrence was not observed in this series but reoperation in the puppies was invariably fatal. Factors contributing to the development of intussusception in the puppies included round worm infestation, recent dietary change following weaning, malabsorption and diarrhoea due to pancreatic insufficiency following pancreatectomy and respiratory infections suggesting an infective origin for the intussusceptions.
Vet Rec 1981 Jan 10
PMID:Canine intestinal intussusception following renal and pancreatic transplantation. 701 80

The effects of whole blood transfusion (trial 1), balanced fluid replacement therapy (trial 2) and fluids plus antibiotics (trial 3) on spontaneously occurring neonatal calf diarrhoea were studied under controlled experimental situations using calves of known immunological status as determined by their zinc sulphate turbidity (ZST) levels. Market Ayrshire or Ayrshire cross Friesian calves were chosen with ZST values between 5 and 15 units. Significant differences were not found in survival, weight gains or days of diarrhoea between treatment and control groups in any of the three trials. In the control groups of trials 2 and 3 ZST units were significantly higher in survivors than in those calves that died. The experimental design used provided a controlled and practical method of testing various treatment programmes with calves of known immunoglobulin levels. The different therapies and the importance of defining the immune status of experimental animals are discussed.
Vet Rec 1980 Sep 13
PMID:Controlled studies of various treatments for neonatal calf diarrhoea in calves of known immunoglobulin levels. 702 Feb 27


<< Previous 1 2 3 4 5 6 7 8 9 10 Next >>