Gene/Protein Disease Symptom Drug Enzyme Compound
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 58,342 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The dirhodium complex Rh(+II)2[(+)-MTPA]4 is introduced as an NMR auxiliary for enantiodifferentiation. As a soft Lewis acid, it is particularly useful for the recognition of soft Lewis base molecules. The donor properties of ligands can be divided into several categories and are exemplified by various classes of phosphorus-containing functionalities. In addition, the thermodynamics of the underlying ligand-complex equilibria are discussed and stereochemical implications demonstrated. The extension of the dirhodium method to absolute configuration determination is evaluated. The outlook for future applications with further non-phosphorus ligands is presented.
Chem Rec 2005
PMID:Rh2[MTPA]4, a dirhodium complex as NMR auxiliary for chiral recognition. 1627 38