Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:Q9UIJ5 (Rec)
 58,342 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A complement fixation test (CFT) based on that used for brucellosis (Brinley Morgan and others 1971) has been developed for use on the sera of horses exposed to the contagious equine metritis (CEM) organism. None of 50 single samples from horses thought to be unexposed to the CEM organism was positive to the test, although five showed inconclusive reactions. Samples were examined from 41 mares either proved to be infected or from an infected stud. Of these 21 were positive, 11 were inconclusive and nine were negative. The relationship of the CFT to reactions in the other tests used in this condition is discussed--the serum agglutination test (SAT) and antiglobulin test (AGT) (Benson and others 1978). Complement fixing antibodies appear to remain for a longer period in the infected animal, and are therefore more likely to be of use in the diagnosis of the chronic carrier state.
Vet Rec 1978 Sep 23
PMID:A complement fixation test for antibody to the contagious equine metritis organism. 71 83

The morphology of human penile blood vessels has been studied to characterize columns of smooth muscle found in the intima. Although previous workers (Kiss, 1921; Conti, 1952) termed these intimal pads or polsters and concluded that they were actively responsible for the production of erection, more recent work has questioned these conclusions (Benson et al., 1980; Newman and Tchertkoff, 1980). Serial sections were taken throughout the length of the penis from 11 cadavers and stained with various histopathological stains. Numerous polster-like structures were found, but all could be identified as either branch points in vessels, intimal cushions located at branch points, or arteriosclerotic lesions at various stages of development. None of these structures seem capable of functioning in the manner attributed to them by Conti (1952) and others. Furthermore, comparison of the structures found in the present study to illustrations of polsters in Conti's paper suggest that these are identical. The present study refutes the polster theory of erection and leaves open to further question the mechanisms involved in the control of blood flow into and within the penis.
Anat Rec 1982 Aug
PMID:The vasculature of the human penis: a reexamination of the morphological basis for the polster theory of erection. 713 2