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Adult cattle in a herd suffering from widespread infection with Brucella abortus biotype 2 were slaughtered during the eradication campaign. A heifer calf fom that herd was moved to a fresh herd which remained apparently free from brucellosis until nine years later when the same animal produced a strongly positive serological reaction and Brucella abortus biotype 2 was isolated from its milk.
Vet Rec 1982 Dec 18
PMID:Latent bovine brucellosis. 715 20

Of 272 heifers subjected to a brucellosis anamnestic test following one injection of K45/20A vaccine, 53 (19%) gave a positive result to the anti-bovine globulin test and 21 (8%) gave a complement fixation test titre at 1/16 or more. Three heifers (1%) gave a positive serum agglutination test (SAT) titre (60 iu or more) 12 weeks after the second injection of K45/20A vaccine. One of the three aborted at seven months' gestation (Brucella abortus culture positive), another had an SAT level of 100 iu 10 days after calving while the SAT titre of the third heifer continued to fall and remain negative after a normal calving. All the remaining heifers continued to give negative SAT. Recommendations are made for interpreting the anamnestic test for the diagnosis of the latent carrier state.
Vet Rec 1980 Mar 15
PMID:Latent carriers of brucellosis. 718 74

Triphenyltetrazolium chloride stained Brucella abortus 0 and Yersinia enterocolitica 09 0 and 0H antigens were used in the microplate agglutination test. It was shown that the results of these tests could be used to differentiate anti-brucella antibodies from antibodies induced by motile Y enterocolitica 09 in cattle sera.
Vet Rec
PMID:The microplate agglutination test: a simple technique to assist in the differentiation of bovine brucellosis and yersiniosis. 743 2

Fifteen different Rose Bengal antigens showed large differences with respect to pH, cell concentration and agglutination with the international standard anti-Brucella abortus serum, demonstrating the lack of international standardisation. Their sensitivity and specificity, compared with that of the complement fixation test, were evaluated for the diagnosis of B melitensis infection in culture-positive sheep, brucella-free ewes, and sheep and goats belonging to field flocks under different epidemiological conditions. All the Rose Bengal antigens and the complement fixation test had 100 per cent specificity when testing brucella-free sheep or animals belonging to flocks in unvaccinated brucellosis-free areas, but there were large differences in sensitivity between the Rose Bengal antigens with sera from culture-positive sheep or from animals belonging to infected flocks. When using the most sensitive antigen, no difference was observed in Rose Bengal sensitivity between animals infected with either biovar 1 or biovar 3 of B melitensis. The relationship between the sensitivity of the Rose Bengal antigens and cell concentration was unclear, but their sensitivity was related to the standardisation of the antigens with the international standard serum. The complement fixation test was less sensitive than the Rose Bengal test when testing culture-positive sheep. When testing sera from animals belonging to infected flocks with antigens standardised according to European Union rules, no great differences were observed in the sensitivities of the two tests. However, great differences in sensitivity between the Rose Bengal antigens were observed with sera from animals belonging to flocks with low levels of prevalence.(ABSTRACT TRUNCATED AT 250 WORDS)
Vet Rec 1994 Apr 16
PMID:Efficacy of different Rose Bengal and complement fixation antigens for the diagnosis of Brucella melitensis infection in sheep and goats. 803 72

Between 1990 and 2000, 317 herds of cattle in Northern Ireland were identified as being seropositive to Brucella abortus, and 68 per cent of them were attributed to transmission from neighbouring herds or to local spread. Of particular significance were three primary outbreaks in 1997, which resulted in significant secondary and tertiary spread. Three spatial clusters were identified, corresponding to two of the primary outbreaks, and the herd density and within-herd spread were highest in the largest cluster. Abortions in an infected herd and the disease-risk status of the disclosure test were positively associated with an increased within-herd prevalence.
Vet Rec 2006 May 27
PMID:Epidemiology of bovine brucellosis in Northern Ireland between 1990 and 2000. 1673 1

Between 2002 and 2007, 75 strains of Brucella abortus were isolated from aborted bovine fetuses collected from several regions of Turkey. The isolates were all identified as B abortus biovar 3 by conventional methods. However, when they were analysed by enhanced amos-ery pcr, a 5.4 kb deletion, different from that in the Tulya strain (B abortus biovar 3, atcc 23450), was identified in all of them. As a result, they were subtyped as B abortus biovar 3b.
Vet Rec 2008 Nov 29
PMID:Characterisation of Brucella abortus biovar 3 isolates from Turkey as biovar 3b. 1904 91

Thirty-five serum samples and six hygroma fluid samples were collected from sexually mature cattle in one herd with clinical signs of brucellosis (abortion and hygromas) in the Western Region of the Gambia in order to isolate and characterise Brucella species. Information on the sex, age, number of calvings, number of abortions, presence of hygromas, and presence of orchitis was also collected for each animal sampled. Twenty-six (74 per cent) of the serum samples were positive in the rose bengal test and 29 (83 per cent) were positive by indirect ELISA. Three isolates of Brucella, biotyped as Brucella abortus biovar 3, were cultured from six hygroma fluid samples. The multiple locus variable number tandem repeat analysis assay clustered the isolates as B abortus with the same profile for the three isolates, suggesting a common origin of contamination.
Vet Rec 2010 Jun 12
PMID:Phenotypic and genotypic characterisation of Brucella strains isolated from cattle in the Gambia. 2054 66


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