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 58,342 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The use of the chiral 1,1'-binaphthyl scaffold to construct chiral ligands can be traced back for a long time. However, the development of bidentate NHC ligands based on the same backbone has only appeared recently. In this account, we describe the design and synthesis of a new family of chiral NHC ligands based on the 1,1'-binaphthyl scaffold and demonstrate the applications of these chiral NHC-metal complexes in the catalyzed oxidative kinetic resolution of secondary alcohols, asymmetric carbon-carbon bond formations, hydrosilylations, and cyclizations of 1,6-enynes. The chiral NHC ligands containing the 1,1'-binaphthyl backbone can be synthesized in good yields from enantiomerically pure 1,1'-binaphthyl-2,2'-diamine. These transition metals coordinated with chiral bidentate NHC ligands exhibit high catalytic activities and good enantioselectivities for a wide range of metal-catalyzed asymmetric reactions.
Chem Rec 2016 12
PMID:Chiral Bidentate NHC Ligands Based on the 1,1'-Binaphthyl Scaffold: Synthesis and Application in Transition-Metal-Catalyzed Asymmetric Reactions. 2766 85

Donor-stabilised silyliumylidene ions, from the parent [R-Si:]+ , are a class of low-valent silicon species which have received increasing research interest in the last several years. This interest began in the fundamental synthesis and characterisation of these compounds, but has since started to include more investigation into their further reactivity after several stable NHC-stabilised silyliumylidene ions were reported. This personal account briefly discusses the history of the still-young field of silyliumylidene ions followed by a more detailed discussion of published work from our group on the further development of silyliumylidene chemistry over the last four years.
Chem Rec 2019 Mar 05
PMID:NHC-Stabilised Silyliumylidene Ions. 3083 49