Gene/Protein Disease Symptom Drug Enzyme Compound
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Our archival researches at the Royal Society reveal that a small envelope attached to a 1675 letter from an Antwerp apothecary, A. Boutens, contained a sample of the 'Ludus' prepared as a remedy for the 'stone disease' then sweeping through Europe, which was first announced in J. B. van Helmont's De lithiasi (1644). After examining the fascination with the medical use of the Ludus (which required the 'alkahest' for its preparation) and the tenacious efforts to procure it, we trace the fortunae of two other ludi in England, brought to and offered by Francis Mercurius van Helmont during his English sojourn. Both eventually found their way to the geologist John Woodward, one of them through Sir Isaac Newton. Finally we show how the allure of the Ludus helmontii vanished, with transformations in mineral analysis and reclassifications from Woodward to John Hill.
Notes Rec R Soc Lond 2014 Sep 20
PMID:Seventeenth-century 'treasure' found in Royal Society archives: the Ludus helmontii and the stone disease. 2525 77

In 1921 Oliver Lodge defended Philosophical Magazine against charges of mismanagement from the National Union of Scientific Workers. They alleged that its editors performed little editorial work, the bulk being done by the publishers, Taylor & Francis. Lodge reassured Nature's readers that the journal did consult its editors, and suggested 'a conservative attitude towards old-established organs is wise; and that it is possible to over-organise things into lifelessness.' The paper explores Lodge's response by considering the editorial arrangements at Philosophical Magazine. Founded in 1798, it remained remarkably unchanged and so appeared old-fashioned when compared with its closest rivals, Proceedings of the Royal Society and Proceedings of the Physical Society. We argue that for Lodge the management of Philosophical Magazine gave it the flexibility and independence required to sustain the kind of physics, also open to accusations of obsolescence, in which he believed.
Notes Rec R Soc Lond 2015 Sep 20
PMID:CONSERVATIVE ATTITUDES TO OLD-ESTABLISHED ORGANS: OLIVER LODGE AND PHILOSOPHICAL MAGAZINE. 2649 80