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A survey for the macroscopic lesions indicative of pneumonic infection in the pig with Haemophilus pleuropneumoniae was made in an abattoir in eastern England. A total of 78 herds located in 11 counties of eastern or central England were seen between December 1982 and August 1983. Lesions were noted in the batches submitted by 44 (56 per cent) of the 78 herds. A further 16 herds (21 per cent) submitted batches containing pigs affected by pleurisy principally of the caudal lobes but without the pneumonic lesions. Lesions suggestive of enzootic pneumonia were also seen in 61 herds (78 per cent). Circumstances restricted corroborative bacteriological examinations to 53 and serological examinations to 33 herds. Strains of H pleuropneumoniae (predominantly serotype 3 but also serotype 2) were isolated from 26 herds. These comprised 22 out of 42 (51 per cent) of those where typically affected plucks, or plucks with caudal lobe pleurisy, were encountered, and four out of 11 (36 per cent) in which there was either no observable thoracic disease or enzootic pneumonia only. Complement fixing antibodies to serotype 3 or 2 antigens occurred in 26 out of 33 herds (79 per cent). These comprised 25 (83 per cent) of 30 herds with batches exhibiting either typical pulmonary lesions and, or, caudal lobe pleurisy and one of three herds without such lesions. Collectively these data indicate that herds containing pigs with pleuropneumonia are common at least in the more easterly parts of England and that H pleuropneumoniae, usually but not always associated with disease, is also widespread.
Vet Rec 1985 Aug 17
PMID:Prevalence of pig herds affected by pleuropneumonia associated with Haemophilus pleuropneumoniae in eastern England. 404 7

Since 1959, the Pig Health Control Association (PHCA) has run a national health-control scheme for pig herds believed to be free from enzootic pneumonia. During this time, many herds developed this disease without a simple explanation. From 1968, 55 such unexplained breakdowns have been studied in detail. The first signs in 50 breakdowns were either coughing in growing pigs (52 per cent of outbreaks), illness in adult stock (34 per cent of outbreaks) or pneumonia in routinely slaughtered pigs (14 per cent of outbreaks). In some outbreaks, enzootic pneumonia appeared to grow out of a pre-existing respiratory infection, which was not identified as enzootic pneumonia, in suckling pigs, suggesting that either Mycoplasma hyopneumoniae was already present in a latent state, or it more readily seeded damaged respiratory tracts from outside. In three outbreaks of this type, where pathological material was collected during the transition period, no laboratory evidence was obtained for the presence of M hyopneumoniae in the primary respiratory disease. Analysis of breakdowns in two national testing stations indicated that clinical/pathological signs might not develop until three to five months after the introduction of an infected group of weaners. It is possible, therefore, that a pig herd might not show obvious signs of the disease until up to six months or more after initial infection. There was little evidence to indicate that unexplained breakdowns arose from long term latent infection in other herds from which stock had been imported. There was considerable evidence, however, to suggest that breakdowns arose from extraneous sources.(ABSTRACT TRUNCATED AT 250 WORDS)
Vet Rec 1984 Sep 29
PMID:Apparent reinfection of enzootic-pneumonia-free pig herds: early signs and incubation period. 649 92

Tiamulin hydrogen fumarate has been shown to be highly active in vitro against Mycoplasma hyosynoviae, an organism that causes arthritis in pigs. A gilt-multiplier herd with a history of this condition was selected to evaluate the efficacy of tiamulin in vivo for the treatment of this disease. The presence of M hyosynoviae was confirmed by its isolation from two typically affected cases. A field trial was carried out on clinically affected pigs, using tiamulin at 10 mg and 15 mg/kg bodyweight given by injection for three consecutive days, by comparing their weight gains and reduction in lameness scores during a seven day trial period (days 0 to 7) with those of negative untreated controls and positive controls injected with lincomycin at 10 mg/kg bodyweight for three days. Both of the tiamulin treatment levels appeared to be effective, as there were marked improvements in weight gains and reduction in lameness scores in comparison with the negative controls. The improvements were similar to those achieved with the positive control, lincomycin.
Vet Rec 1984 Dec 08
PMID:Use of tiamulin in a herd of pigs seriously affected with Mycoplasma hyosynoviae arthritis. 652 89

An investigation into the health and husbandry of 15 small poultry flocks was undertaken. Each flock was visited in July and a questionnaire on management practices and disease history was completed. The flocks were clinically examined and serological tests for Salmonella pullorum, Mycoplasma gallisepticum, M synoviae, M meleagridis, Newcastle disease, infectious bursal disease, infectious bronchitis, eggdrop syndrome 76, adenoviruses and reoviruses were carried out. Oesophageal and cloacal swabs were cultured for mycoplasma and pullorum reactors were cultured. M gallisepticum, M synoviae, M meleagridis and M gallinarum infections were detected and serological reactions for all the viral diseases, except egg drop syndrome 76, were found. Evidence of Newcastle disease and pullorum disease was encountered. Lice were present in five flocks and mites in four flocks. Welfare standards varied.
Vet Rec 1982 Sep 11
PMID:Survey of the health and husbandry of small poultry flocks in Great Britain. 681 44

Mycoplasma bovis infection was eradicated from a naturally infected dairy herd in Great Britain by a programme of identification, segregation and culling of infected animals. A series of group and whole milking herd tests was carried out over a period of 15 months, followed by a whole herd nasal swabbing. Cows were also sampled after calving and at drying off and bulk tanks were sampled at weekly intervals during the same period and for a further nine months. Fifty-nine cows were identified as excretors, the majority in group or herd tests, but five after calving and three at drying off. Eight of the original clinical cases were retained in the herd, after repeated negative test results. Bulk tank sampling was found to be extremely useful in detecting infection even down to one cow in a milking herd of 300. The value of milking hygiene and the indications for eradication are also discussed.
Vet Rec 1983 Mar 26
PMID:Eradication of Mycoplasma bovis infection from a dairy herd in Great Britain. 684 9

A group of six racing pigeons naturally infected with Mycoplasma columborale and M columbinum were housed in isolation and treated with tiamulin hydrogen fumarate in the drinking water for 35 days. Swabs from the oropharynx, the oesophagus and the trachea were negative for mycoplasmas at the end of this period. Mycoplasmas were recovered from two of the birds after a further nine days, and 13 weeks after the cessation of treatment mycoplasmas were recovered from all six birds.
Vet Rec 1983 Apr 02
PMID:Treatment of racing pigeons naturally infected with Mycoplasma columborale and M columbinum. 685 69

A mycoplasma-like organism was isolated from five cows with chronic incurable mastitis from one dairy herd. This organism was shown to be Mycoplasma californicum and was used to infect three cows by intramammary inoculation. The challenge organism was reisolated from all the infected quarters and the ensuing inflammatory response produced a chronic mastitis with a permanent drop in milk yield. Antibiotic treatment in one animal was unsuccessful.
Vet Rec 1982 Jun 19
PMID:Isolation of Mycoplasma californicum from an outbreak of bovine mastitis and the experimental reproduction of the disease. 711 77

An acute pneumonia developed in 28 calves which had been housed together from one to two weeks of age. The clinical signs included pyrexia, tachypnoea, respiratory distress and coughing. Some of the calves died. The pneumonia was characterised by an alveolitis with multinucleated syncytia, alveolar epithelial hyperplasia and bronchiolitis. Interstitial emphysema was also present. Fifteen of 19 calves examined serologically had rising neutralising antibody titres to respiratory syncytial virus; in nine calves the rise was fourfold or greater. Respiratory syncytial virus was not isolated from the calves. There was no evidence of parainfluenza type 3 virus involvement. The adult cows being sucked by the calves remained clinically normal throughout the incident. Six calves examined six weeks after the outbreak started had a chronic cuffing pneumonia characterised by lymphocytic bronchiolitis; some of the calves also had bronchiolitis obliterans. Mycoplasma dispar was found in two of them.
Vet Rec 1981 May 09
PMID:Acute fatal pneumonia in calves due to respiratory syncytial virus. 725 27

A total of 656 lung specimens comprising 196 grossly pneumonic lungs from clinically diseased pigs and 230 grossly pneumonic and normal lungs from abattoirs were cultured for mycoplasmas. Mycoplasmas or acholeplasmas were recovered from 102 lung specimens, of which 28 were serologically identified (by disc growth inhibition and agar gel diffusion tests) as Mycoplasma suipneumonia, 14 as M hyorhinis, 35 as Acholeplasma granularum and 4 as A laidlawii. In addition, 15 isolates were unclassified and six were not typed. Mycoplasmas isolated from the suspect enzootic pneumonic lungs: slaughterhouse pneumonic lungs: normal lungs were in the ratio of 3:2:1. M suipneumonia, A granularum and A laidlawii were isolated from both normal and pneumonic lungs of pigs while M hyorhinis was only isolated from pneumonic ones. A close antigenic relationship between M suipneumonia and A granularum was demonstrated.
Vet Rec 1981 Jan 24
PMID:Isolation and identification of mycoplasmas from pig lungs in Singapore. 725 51

Mycoplasma meleagridis was isolated from both normal and diseased air sacs of turkeys examined and graded for air sacculitis on the evisceration line in a processing plant. It was also cultivated from wing bone cavities of turkeys with severe air sac lesions but not from leg bones or from samples of deep muscle. A further investigation, using material taken randomly from the condemned meat container, confirmed that M meleagridis was recoverable from wing bones.
Vet Rec 1980 Mar 29
PMID:The distribution of Mycoplasma meleagridis in normal turkey carcases and those affected with air sac disease. 739 24


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