Gene/Protein Disease Symptom Drug Enzyme Compound
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 58,342 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Levamisole is an anthelmintic drug which also has immunomodulatory properties. The application of these immunomodulatory properties in the prevention and, or, treatment of bovine mastitis is considered. In the light of the available evidence on the use of levamisole against mastitis and of our understanding of the pathogenesis of mastitis it is thought that the prospect of using levamisole beneficially is limited. However, drying-off and parturition are two times at which levamisole may have rational application in mastitis prevention.
Vet Rec 1984 Feb 11
PMID:Levamisole and bovine mastitis. 670 86

During the past four years this practice has monitored the incidence of mastitis and treatments on farms involved in a mastitis control scheme. This paper outlines the major features of the control programme from the practice point of view and analyses the data collected during the monitoring.
Vet Rec 1984 Mar 17
PMID:Mastitis monitoring in general practice. 671 Aug 19

Listeria monocytogenes type 4 was isolated from milk of a cow affected with mastitis in the left fore quarter. Histological examination revealed a severe suppurative mastitis with eosinophil leucocytes predominating among the inflammatory cells. The findings and the public health aspect of the condition are discussed.
Vet Rec 1980 Oct 25
PMID:Listeria monocytogenes infection in bovine mastitis. 677 10

Five hundred herds were examined to determine the prevalence of subclinical mastitis in the British dairy herd. The prevalences of the various infections recorded were Streptococcus agalactiae 3.4 per cent of quarters, S dysgalactiae 1.1 per cent, S uberis 1.5 per cent and Staphylococcus pyogenes 8.1 per cent. There were regional differences in the prevalence of some of these pathogens. The national prevalence of subclinical mastitis as defined by the International Dairy Federation was 9.6 per cent of all quarters. Udder infections were less prevalent in herds where mastitis control measures were being used. The prevalence of infection also declined as the size of herd increased. However, as the uptake of mastitis control measures was greater in the larger herds it seems likely that the widespread use of control measures was the most important factor responsible for the relatively low prevalence of subclinical mastitis.
Vet Rec 1980 May 24
PMID:A survey of mastitis in the British dairy herd. 700 18

During the course of a study of an outbreak of mastitis in a dairy herd, an aerotolerant campylobacter was isolated from a milk sample. This organism was cultured and the right front quarters of four young Friesian cows were infected by intramammary inoculation. Each infected quarter developed an acute clinical mastitis which resolved spontaneously after 120 hours. The challenge organism was reisolated from one of the quarters.
Vet Rec 1982 Mar 06
PMID:Mastitis in dairy cows associated with an aerotolerant campylobacter. 708 Apr 8

In the light of experimental work using the mouse model of staphylococcal mastitis and supported by material from staphylococcal mastitis in cows a progressive pathology of the disease in cattle is proposed. The rationale of the standard control measures (dry cow therapy, teat dipping, etc) is defended, the possibility of immunisation is doubted but the prospect of advances in therapy is thought to be good.
Vet Rec 1982 Apr 17
PMID:Progressive pathology of staphylococcal mastitis with a note on control, immunisation and therapy. 708 Apr 29

A mycoplasma-like organism was isolated from five cows with chronic incurable mastitis from one dairy herd. This organism was shown to be Mycoplasma californicum and was used to infect three cows by intramammary inoculation. The challenge organism was reisolated from all the infected quarters and the ensuing inflammatory response produced a chronic mastitis with a permanent drop in milk yield. Antibiotic treatment in one animal was unsuccessful.
Vet Rec 1982 Jun 19
PMID:Isolation of Mycoplasma californicum from an outbreak of bovine mastitis and the experimental reproduction of the disease. 711 77

Following a sudden drop in milk yield in a large dairy herd, leptospiral mastitis due to serotype hardjo was diagnosed serologically and by isolation of the organism from the milk and urine of affected cows. Two milkers subsequently became ill and developed titres to the Hebdomadis serogroup. During the same period the neighbouring herd experienced poor milking performance and a series of abortions and serological evidence suggested recent hardjo infection. The common source of infection appeared to be infected down calving heifers.
Vet Rec 1980 Sep 27
PMID:Mastitis and abortion in dairy cattle associated with Leptospira of the serotype hardjo. 721 Apr 29

Errors in management, other than nutrition, which can be predisposing causes of disease, eg, walking on abrasive surfaces and prolonged standing in slurry (which precipitate lameness), faulty milking and a dirty environment (which are conducive to mastitis), breeding to produce oversized fetuses (leading to dystocia) and inefficient observation (leading to a failure to detect oestrus) are described. Nutritional factors affecting conception rates and the occurrence of the metabolic diseases, ketosis, hypocalcaemia and hypomagnesaemia are outlined.
Vet Rec 1981 Jun 27
PMID:Husbandry methods predisposing to production diseases in dairy cows. 730 39

Gross abnormalities of the mammary glands of 1650 culled ewes were recorded. Clinically obvious lesions were detected in 211 (12.8 per cent) of udders; 77 per cent of lesions were abscesses. A generalised calcification of the whole of a gland was observed in 23 udders. It is concluded that abnormalities of the udder are an important reason for the culling ewes. The assessment of the cost-effectiveness of measures to reduce the incidence of mastitis would be worthwhile.
Vet Rec 1981 Oct 17
PMID:Observations on the mammary glands of culled ewes at the time of slaughter. 732 53


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