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Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
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Target Concepts:
Gene/Protein
Disease
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Query: UNIPROT:Q9UIJ5 (
Rec
)
58,342
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The snouts of 2701 pork, bacon and heavy pigs killed at five abattoirs in England and Scotland during March to July 1974 were examined for evidence of atrophic rhinitis. Lesions were graded 1 to 5 according to severity. Suspicious lesions were present in 75-7 per cent of the sample. There was obvious atrophy of the turbinates in 44-7 per cent (grade 2 to 5) and severe atrophy in 17-5 per cent (grades 3 to 5). Foreign bodies were found in or between the posterior cheek teeth of 5-3 per cent of the sample. There was frequently an associated
gingivitis
. Other lesions seen included black discolouration of the teeth, severe tooth wear and osteoarthrosis of the temporomandibular joint. It was concluded that the incidence of atrophic rhinitis could have increased markedly since the last survey of the United Kingdom was undertaken in 1956/57 and some form of disease-monitoring service was urgently needed.
Vet
Rec
1975 Jun 14
PMID:Atrophic rhinitis of pigs: abattoir studies. 113 31
Isolation rates of feline herpesvirus (FHV) and feline calicivirus (FCV) from oropharyngeal swabs, taken from 6866 cats in 1980 to 1989 were studied retrospectively. FCV was isolated from 1364 (19.9 per cent) and FHV from 285 (4.2 per cent). The ratio of FCV:FHV isolations varied from 1.3:1 to 15:1 in individual years with an overall ratio of 4.8:1. Isolation of both viruses was fairly uniform for each year and there was no breed or sex disposition to either virus. Of 872 cats shedding FCV and 213 cats shedding FHV, of known age, 447 (51.3 per cent) with FCV and 140 (65.7 per cent) with FHV were under one year old, compared to only 35.3 per cent of the whole population sampled. For the years 1985 to 1989, more information was obtained about the cases. Of 4626 cats tested, 1180 (25.5 per cent) had acute upper respiratory tract disease (URTD) of which 348 (29.5 per cent) were shedding FCV and 162 (13.7 per cent) FHV. A further 597 had chronic URTD and of these, 102 (17.1 per cent) were shedding FCV and 18 (3 per cent) FHV. In 120 cases of suspected vaccine reaction/breakdown, FCV was isolated from 34 (28.3 per cent) and FHV from only two (1.7 per cent). FHV was not isolated from any of 412 cases presenting with chronic
gingivitis
/stomatitis alone; 181 (43.9 per cent) were shedding FCV and when cats with other signs in addition to chronic
gingivitis
were included, this proportion increased to 70.4 per cent.(ABSTRACT TRUNCATED AT 250 WORDS)
Vet
Rec
1991 Jan 26
PMID:Isolation of feline calicivirus and feline herpesvirus from domestic cats 1980 to 1989. 185 Jan 83
A representative sample of the pet cat population of the United Kingdom was surveyed. Blood samples from 1204 sick and 1007 healthy cats of known breed, age and sex were tested for antibodies to feline immunodeficiency virus (FIV) and feline leukaemia virus (FeLV). The prevalence of FIV was 19 per cent in sick cats and 6 per cent in healthy cats, and the prevalence of FeLV was 18 per cent in sick cats and 5 per cent in healthy cats; both infections were more common in domestic cats than in pedigree cats. Feline immunodeficiency virus was more prevalent in older cats but FeLV was more prevalent in younger cats. There was no difference between the prevalence of FeLV in male and female cats but male cats were more likely to be infected with FIV than female cats. No interaction was demonstrated between FIV and FeLV infections. Of the cats which were in contact with FIV in households with more than one cat, 21 per cent had seroconverted. The prevalence of FeLV viraemia in cats in contact with FeLV was 14 per cent. The clinical signs associated with FIV were pyrexia,
gingivitis
/stomatitis and respiratory signs, and with FeLV, pyrexia and anaemia. It was concluded that both viruses were significant causes of disease, and that the cats most likely to be infected with FIV were older, free-roaming male cats and for FeLV, younger, free-roaming cats.
Vet
Rec
1989 Sep 09
PMID:Prevalence of feline leukaemia virus and antibodies to feline immunodeficiency virus in cats in the United Kingdom. 255 56
Thirty-two cats referred to the Feline Studies Centre between June 1987 and October 1988, and 14 in-contact cats, were found to be infected with feline immunodeficiency virus. Most of the 46 cats were non-pedigree and free ranging; 27 were male (19 neutered) and 19 were female (18 neutered). Their ages ranged from one to 17 years and the average age was 5.8 years. The most common clinical signs were lethargy, inappetence, weight loss, pyrexia and lymphadenopathy; most cases had multiple abnormalities. Other common signs were
gingivitis
, diarrhoea, rhinitis and ocular discharge. Eight cats had neoplasia. The commonest haematological abnormalities were anaemia, neutropenia, lymphopenia and monocytosis. Eight cats had lymphocytosis; seven of these were in a single house-hold. Several cats had high serum globulin levels and half of those tested had high IgG levels. Seven cats had no detectable antibody to feline immunodeficiency virus even though the virus was cultured from the peripheral blood lymphocytes. During follow-up for up to 60 weeks one cat died and 23 were destroyed on humane grounds.
Vet
Rec
1989 Sep 23
PMID:Clinical and laboratory findings in cats infected with feline immunodeficiency virus. 255 57
The inadvertent introduction of feline calicivirus into a colony of 19 experimental cats, 13 of which were infected with feline immunodeficiency virus, resulted in the development of chronic
gingivitis
in nine animals. Of these, six were infected with both viruses, one with the immunodeficiency virus alone and two with the calicivirus alone. The
gingivitis
was generally more severe in the cats infected with both viruses, suggesting that feline immunodeficiency virus may make cats infected with calicivirus more susceptible to chronic
gingivitis
.
Vet
Rec
1993 Apr 03
PMID:Chronic gingivitis in a colony of cats infected with feline immunodeficiency virus and feline calicivirus. 838 10
The prevalence and populations of Porphyromonas and Prevotella species were determined in three samples of dental plaque from each of 34 healthy dogs. Porphyromonas gingivalis was present in 68 per cent of the dogs and 47 per cent of the plaque samples. The counts of P gingivalis increased with age (P < 0.1), the amount of plaque (P < 0.05) and the degree of
gingivitis
(P < 0.1). Prevotella intermedia was present in 44 per cent of the dogs and 23 per cent of the plaque samples. The counts of P intermedia were correlated with the amount of plaque (P < 0.05) and the degree of
gingivitis
(P < 0.1). Porphyromonas canoris, P salivosa, P cangingivalis, P cansulci, P crevioricanis and Prevotella denticola were isolated from only 9, 6, 3, 3, 3 and 3 per cent of the dogs, respectively. Porphyromonas gingivicanis was not isolated from any of the animals sampled. There was a highly significant (P < 0.001) correlation between the amount of plaque, the extent of
gingivitis
and the age of the dog.
Vet
Rec
1997 Feb 08
PMID:Prevalence of Porphyromonas and Prevotella species in the dental plaque of dogs. 905 Jan 76
Fifteen cats from Italy with Ehrlichia-like inclusion bodies in their neutrophils were studied. They were diagnosed with Anaplasma (Ehrlichia) phagocytophilum infection on the basis of cytological observation of morulae within 1 to 21 per cent of their neutrophils, clinical signs characteristic of ehrlichiosis and their response to doxycycline. The predominant signs of disease were anorexia, lethargy, hyperaesthesia, muscle and joint pain, lameness, neck rigidity, lymphadenomegaly,
gingivitis
/periodontitis, conjunctivitis, weight loss, incoordination, pale mucous membranes and hyperglobulinaemia. The cat with inclusions in 21 per cent of its neutrophils had suffered arthralgia, tachypnoea, neck rigidity, vomiting and thrombocytopenia for four months, but recovered promptly after treatment with doxycycline.
Vet
Rec
2005 Jun 11
PMID:Microscopic and clinical evidence for Anaplasma (Ehrlichia) phagocytophilum infection in Italian cats. 1595
Seventeen Lancefield group C streptococci (13 Streptococcus equi zooepidemicus and four Streptococcus dysgalactiae equisimilis) and 185 Lancefield group B streptococci (Streptococcus agalactiae) were isolated from camels (Camelus dromedarius) in Kenya and Somalia; 59 of the isolates were from healthy nasopharynx, vaginal and rectal mucosa and from non-abscessed lymph nodes, and the other 143 isolates were from clinical infections of the respiratory tract, tick bite lesions, abscessed lymph nodes, abscesses and other purulent skin lesions, periarthritis and arthritis, puerperal infection and
gingivitis
. The role of Lancefield group B and C streptococci as commensals and common opportunistic pathogens in East African camels is described.
Vet
Rec
2007 Mar 10
PMID:Lancefield group B and C streptococci in East African camels (Camelus dromedarius). 1735 Nov 74
Between 2002 and 2005 210 rabbits, 257 guinea pigs and 123 chinchillas were examined; oral disease was diagnosed in 38.1 per cent of the rabbits, 23.4 per cent of the guinea pigs and 32.5 per cent of the chinchillas. In the rabbits, the maxillary right P3, mandibular right P3, P4 and M1 and mandibular left P3, P4, and M1 were the teeth most frequently affected; in the guinea pigs, the mandibular right P4 and both the mandibular left incisor and P4 were most often affected; and in the chinchillas the maxillary right P4 and M1 and maxillary left P4 were most often affected. The incisors and first mandibular cheek teeth of the guinea pigs were significantly more often affected than those in the chinchillas or rabbits. Bilateral lesions of the maxillary cheek teeth were significantly more common in the chinchillas. The highest incidence of gingival hyperplasia was recorded in the rabbits. The incidence of gingival erosions and
gingivitis
were significantly higher in the chinchillas.
Vet
Rec
2008 Apr 05
PMID:Quantitative and qualitative assessments of intraoral lesions in 180 small herbivorous mammals. 1839 Aug 54
Cheek teeth (CT) diastemata are now recognised as a clinically significant equine disorder, but their prevalence in the general equine population is unknown. There is also limited information on the signalment of affected horses; the more commonly affected Triadan sites; and the shape and clinical characteristics of CT diastemata. During the 12-month study period (2008 to 2009), standardised records were obtained during routine dental examinations performed by five veterinarians in a first-opinion equine practice. Cheek teeth diastemata were identified in 49.9 per cent of all horses (n=471) of mean age 11 years (range one to 30 years), with 83.5 per cent of all diastemata affecting mandibular CT and 16.5 per cent affecting maxillary CT. The mean number of diastemata per case was 1.7 (range one to 20) and the mandibular 07 to 08 position was most commonly affected. Valve diastemata were more common (72.1 per cent prevalence) than open diastemata (27.9 per cent). Food trapping was present in 91.4 per cent of diastemata, with
gingivitis
and periodontal pockets adjacent to 34.2 per cent and 43.7 per cent, respectively. Halitosis was present in 45.5 per cent of affected horses. There was an age-related increase in both the prevalence of diastemata, and in the numbers of diastemata per affected horse, and horses over 15 years old had a significantly increased proportion of open diastemata.
Vet
Rec
2012 Jul 14
PMID:Prevalence and some clinical characteristics of equine cheek teeth diastemata in 471 horses examined in a UK first-opinion equine practice (2008 to 2009). 2280 49
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