Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UNIPROT:Q9UIJ5 (Rec)
 58,342 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Enterobacterial plasmid genes mucAB, which possess error-prone repair activity, were cloned and sequenced independently of a sequence previously determined (K.L. Perry, S.J. Elledge, B.B. Mitchell, L. Marsh, and G.C. Walker, Proc. Natl. Acad. Sci. USA 82:4331-4335, 1985). The survival- and mutation-enhancing activities of mucAB ligated to the MLSr promoter of a Bacillus subtilis plasmid in the shuttle vector pTE22R were expressed in B. subtilis as well as in Escherichia coli after mutagenic treatment. mucAB fragments with 5' deletions of various lengths up to the base sequence encoding Ala-26-Gly-27, the putative RecA-mediated cleavage site of the MucA protein, showed mutation-enhancing activity for noninducible lexA3 E. coli when ligated to the MLSr promoter in frame. This activity was lost by extending the deletion downstream. The formations of MucA and MucB proteins in B. subtilis and E. coli were demonstrated by Western blot (immunoblot) analysis. MucA cleavage in Rec+ B. subtilis was observed only after treatment with an alkylating agent and was not observed in RecA- and RecE- strains, whereas in E. coli cleavage was observed in Rec+ cells after treatment with either mitomycin C or an alkylating agent but was not detected in RecA- cells. Common activity of B. subtilis Rec and E. coli RecA in the induction of mutants is suggested.
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PMID:Heterospecific expression of misrepair-enhancing activity of mucAB in Escherichia coli and Bacillus subtilis. 190 11

The clinical disturbance resulting from section of the sympathetic in the neck; miosis, decreased sweating, increased vascularity and narrowing of the palpebral fissure is universally recognized while the definitive sympathetic pathways remain unknown. Most current texts depict a plexus along the surface of the parasellar carotid as part of that pathway although a previous review leaves the large connection of the carotid sympathetic to the sixth and then to the first division of the fifth cranial nerve as a putative pathway. Recent reports of complete tears of the parasellar carotid without sympathetic changes tend to further discount a carotid plexus as a pathway and focus attention on the direct carotid sympathetic nerve connections to the sixth and fifth cranial nerves as probable but unproven pathways, the interruption of which, result in Bernard, Mitchell, Horner Syndrome. (Parkinson '79).
Anat Rec 1988 Jan
PMID:Further observations on the sympathetic pathways to the pupil. 334 84

This article has been prepared by the APHA Small Ruminant Expert Group and Sian Mitchell, the APHA's parasitology champion.
Vet Rec 2016 Sep 03
PMID:Parasitic gastroenteritis in sheep. 2758 94

This article has been prepared by Paul Duff, Sian Mitchell and Colin Weaver on behalf of the APHA Wildlife Expert Group and Becki Lawson of Garden Wildlife Health.
Vet Rec 2018 06 02
PMID:Wildlife mass mortality events associated with harsh winter weather. 2985 15

This focus article has been prepared by Mick Macrelli, Lizzy Dunnett, Sian Mitchell and Amanda Carson of the APHA Small Ruminant Species Expert Group.
Vet Rec 2019 05 04
PMID:Coccidiosis in sheep. 3132 May 75

This focus article has been prepared by Sian Mitchell, veterinary investigation team lead of the APHA Carmarthen veterinary investigation centre.
Vet Rec 2019 12 07
PMID:Surveillance for disease in extensively managed livestock. 3180 29

This focus article has been prepared by Amanda Carson, Sian Mitchell, Paul Phipps, Michele Macrelli and Elizabeth Dunnett of the APHA.
Vet Rec 2020 Apr 04
PMID:Tickborne diseases of sheep. 3224 64