Gene/Protein Disease Symptom Drug Enzyme Compound
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On the basis of earlier studies, a programme for eradicating exogenous avian leukosis virus from commercial poultry stock was devised and applied to 11 layer breeder lines. After three years of testing, avian leukosis virus infection was eradicated completely from all but one, a slow-feathering line.
Vet Rec 1991 Jan 05
PMID:Eradication of exogenous avian leukosis virus from commercial layer breeder lines. 184 81

The avian leukosis viruses (ALVs) are a major group of retroviruses associated with neoplastic diseases in poultry. The ALV-J strain was identified as a cause of myelocytomas in broiler breeder and broiler chickens in the UK in the 1980s; however, following eradication of the virus,commercial broilers have remained free of infection since the early 2000s. A pet chicken was submitted to Animal and Plant Health Agency (APHA) in 2013 with a history of croaking respirations, abnormality of the left eye and apparent paralysis. Postmortem examination of the bird showed widespread tumour-like infiltration of many organs, including the pectoral muscles, internal organs, sternum and ribs. Histopathological examination of the affected tissues revealed myelocytoma formation typical of the lesions associated with ALV-J, and the virus was confirmed by PCR testing and sequencing. Virus was not detected in blood samples in the other five chickens remaining in the flock. The source of infection was not established. This was the first time ALV-J had been seen in the UK since its eradicationand the case highlights the importance of continued surveillance of backyard and hobby chickens to detect potential new and re-emerging disease threats, such as ALV-J, which may be of significance to the wider poultry population.
Vet Rec 2018 01 06
PMID:Avian leukosis virus subgroup J-associated myelocytoma in a hobby chicken. 2908 20