Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UNIPROT:Q9UID3 (FFR)
 233 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Stent thrombosis is a lethal complications and most important unresolved issues of the current PCI. For stent thrombosis prophylaxis of DES implantation patient, there is not a plan of surgery within six months at least, bleeding risk is low, to select patients with good adherence, and a new generation of low-thrombosis DES when implanted select the DES, and then select the appropriate stent size, the length using IVUS, OCT, the FFR, and without creating a dissection at the edges in the high-pressure expansion, and perform sufficient expansion, DAPT after surgery is at least 12 months it is desirable, but it is necessary to consider the balance of the benefit of thrombosis prophylaxis and risk of bleeding DES implantation site, the patient, to determine drug resistance, drug combination be considered in individual cases the selection DAPT period, the single agent.
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PMID:[Antiplatelet therapy after drug-eluting stent implantation]. 2516 28

So-called 'significant' atherosclerotic coronary stenosis is defined by a simple binary morphological index of tightness - percent diameter stenosis (%DS >50 %). Invasive diagnosis of atherosclerotic coronary lesions classically comprises two consecutive stages, which can be fairly accurately described as angiographic visual perception and functional deduction. This anatomic-functional duality should be seen as not so much antithetic as causal and finally quite complex. The present update seeks to: define the ambiguous relationship between functional impact and morphology in atherosclerotic coronary stenosis; to specify the means of invasive diagnosis complementing coronary angiography to compensate the anatomic and functional limitations intrinsic to the latter (cross-sectional intravascular ultrasound [IVUS] and optical coherence tomography [OCT] imaging and fractional flow reserve [FFR] determined by pressure guide); and to bring these preliminary considerations to bear on the design of algorithms to guide the use of complementary invasive diagnostic exploration and draw up a novel diagnostic strategy in interventional cardiology (first-line coronary angiography).
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PMID:The Anatomic-Functional Duality of So-called 'Significant' Atherosclerotic Stenosis - Update on Invasive Diagnostic Strategies in Coronaropathy. 2958 62

Coronary bifurcations are involved in 15-20% of all percutaneous coronary interventions (PCI) and remain one of the most challenging lesions in interventional cardiology in terms of procedural success rate as well as long-term cardiac events. The optimal management of bifurcation lesions is still debated but involves careful assessment, planning and a sequential provisional approach. The preferential strategy for PCI of bifurcation lesions remains to use main vessel (MV) stenting with a proximal optimisation technique (POT) and provisional side branch (SB) stenting as a preferred approach. Final kissing balloon inflation is not recommended in all cases. In the minority of lesions where two stents are required, careful deployment and optimal expansion are essential to achieve a long-term result. Intracoronary imaging techniques (IVUS, OCT) and FFR are useful endovascular tools to achieve optimal results.
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PMID:[Hot issues in bifurcation lesions PCI in 2019]. 3154 2