Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:Q9UE34 (fibrinogen)
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Human Gene/Protein
LRCH4 10.0
zinc finger protein 70 10.0
FIBCD1 protein 10.0
effector cell proteinase receptor 1 10.0
ERI2 10.0
zinc finger protein 160 10.0
fibrinogen 10.0
fibrinogen C domain containing 1 10.0
Dioxin-inducible cytochrome P450 10.0
coagulation factor I 10.0
integrator complex subunit 4 10.0
erythrocyte membrane protein 4.1N 10.0
chromosome 10 open reading frame 104 10.0
zinc finger protein 483 10.0
rheumatoid factor RF-IP20 10.0
AAAP-40 9.6
F-actin capping protein alpha-1 subunit 9.5
FGB 9.3
FIBCD1 9.3
FGG 9.2
Microfibril-associated glycoprotein 4 9.0
MAPK1IP1L 9.0
EMI5 9.0
plasmin precursor 9.0
truncated coagulation factor VIII 9.0
F11R protein 9.0
HLA-DR beta1 9.0
TNFR1B 9.0
Fibrinogen C domain containing 1 9.0
heat shock 70 kDa protein 9B 9.0
HFREP-1 9.0
complement component 1, q subcomponent, A chain 9.0
SH3 domain-binding glutamic acid-rich-like protein 3 9.0
ZBTB11 9.0
SPUVE 9.0
Carboxypeptidase, vitellogenic-like 9.0
complement Factor H-related protein 1 9.0
Prenylcysteine lyase 9.0
Fibrinopeptide A 9.0
alpha 2-plasmin inhibitor 8.7
FDP 8.7
fibrinogen alpha chain 8.6
beta-fibrinogen 8.6
intelectin 2 8.5
EBP-37 8.5
LRRC28 8.5
calcium-promoted Ras inactivator 8.5
Alcohol dehydrogenase 1C 8.5
ADP-ribosylation factor-like protein 1 8.5
fibrinogen beta chain 8.4
glycoprotein IIIa 8.4
PAC-1 8.3
GPIIb 8.3
p58c-fgr 8.2
proaccelerin 8.2
fibrinogen-like 8.1
antithrombin III 8.1
KIAA0649 8.0
ACTE 8.0
CYHR1 8.0
P26s4 8.0
Histone deacetylase 10 8.0
Antithrombin-III 8.0
Glycoprotein IIb 7.9
factor XIIIa 7.9
TPSB2 7.9
thromboplastin 7.8
Antithrombin III 7.8
coagulation factor II 7.7
factor VII 7.7
SLC35D3 7.7
mitochondrial solute carrier protein 7.7
TRBC1 7.7
AGPB 7.7
glycoprotein IIb 7.7
Histidine-rich glycoprotein 7.7
Hepassocin 7.7
prothrombin 7.6
plasminogen 7.6
GPIIIa 7.6
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Disease
Hypodysfibrinogenemia 10.0
Acquired dysfibrinogenemia 10.0
RP34 10.0
Acquired hypofibrinogenemia 10.0
Postpartum deep vein thrombosis 10.0
Vascular atheroma 10.0
Congenital dysfibrinogenemia 10.0
Congenital afibrinogenemia 9.9
afibrinogenemia 9.6
dysfibrinogenemia 9.6
Coronary artery reocclusion 9.5
FGG 9.2
hypofibrinogenemia 9.1
Severe toxemia 9.0
Borrelia recurrentis infection 9.0
Arterial infection 9.0
XLTT 9.0
Segmental hyalinosis 9.0
pyroglobulinemia 9.0
Systemic fibrinogenolysis 9.0
Postoperative deep vein thrombosis 8.8
DIC in newborn 8.5
Neonatal isoerythrolysis 8.5
Vitreous membranes 8.5
Thrombophlebitis migrans 8.5
Postoperative intra-abdominal abscess 8.5
hyperheparinemia 8.5
Retinal arteriovenous nicking 8.5
DECD 8.3
Acute coagulopathy 8.2
Glanzmann 8.2
Glanzmann's thrombasthenia 8.0
Megakaryocytic hyperplasia 8.0
Factor II mutation 8.0
Traumatic reticuloperitonitis 8.0
Citrate toxicity 8.0
HAE III 8.0
Skin hemorrhage 8.0
CONSUMPTION 8.0
Cryofibrinogenemia 7.9
Hypotriglyceridemia 7.7
Post MI 7.7
Segmental glomerulosclerosis 7.7
Generalized atherosclerosis 7.7
cardiovascular infection 7.6
Liver hematoma 7.5
Recurrent urticaria 7.5
von Willebrand disease type 2A 7.5
YSS 7.5
Acute idiopathic thrombocytopenic purpura 7.5
adult APL 7.5
von Willebrand disease type 2A 7.5
Hereditary amyloidosis 7.3
XDP 7.3
disseminated intravascular coagulation 7.1
clotting factor deficiency 7.0
Masugi nephritis 7.0
circulating anticoagulants 6.8
Generalized obesity 6.7
Pericardial calcification 6.6
cigarette abuse 6.6
Gastrointestinal inflammation 6.6
Relative polycythaemia 6.6
coagulopathy 6.6
hemorrhagic diathesis 6.5
Owren 6.5
platelet disorder 6.5
Stauffer's syndrome 6.5
Renal vasculitis 6.5
Bacteroides infection 6.5
coronary thrombosis 6.4
Shwartzman reaction 6.4
Thrombophilia 6.4
Equine grass sickness 6.3
Equine viral arteritis 6.3
dual personality 6.3
Euthyroid sick syndrome 6.3
Activated protein C resistance 6.3
Transmural myocardial infarction 6.2
Lipodermatosclerosis 6.2
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Symptom
Suffocated 10.0
decreased skin turgor 6.9
Local swelling 6.3
jaundice of the skin 6.0
Breast tenderness 6.0
hyperosmia 5.9
toe pain 5.6
Intermenstrual bleeding 5.0
Orthostasis 4.9
dacryops 4.8
cardialgia 4.3
BHS 4.3
monoplegia 4.3
Flu-like symptoms 4.2
polymyalgia 4.2
PAIN 3.9
labored breathing 3.9
HSA 3.6
respiratory problem 3.4
hepatosplenomegaly 3.3
pedal edema 3.3
localized edema 3.3
angina 3.3
cardiovascular impairment 3.3
No pain 3.3
hypoproteinemia 3.1
Signs and Symptoms 2.9
oliguria 2.9
colic 2.9
leg cramps 2.8
autodigestion 2.7
leg edema 2.6
throat irritation 2.6
jaw pain 2.5
catarrh 2.5
nasal discharge 2.4
tachypnea 2.3
atypical chest pain 2.3
livedo 2.3
hepatomegaly 2.2
disturbed balance 2.2
hemiplegia 2.1
hypothermia 2.0
splenomegaly 2.0
swollen joints 2.0
respiratory distress 2.0
dark urine 1.9
night sweats 1.8
arthralgia 1.8
No adverse effect 1.7
overweight 1.7
myalgia 1.7
Physical findings 1.7
meningism 1.6
cyanosis 1.6
chest pain 1.6
muscle rigidity 1.6
hangover 1.5
Poor sleep 1.5
prostration 1.5
anorexia 1.5
eye pain 1.5
mastalgia 1.5
irregular bleeding 1.4
exhaustion 1.4
intestinal bleeding 1.4
renal colic 1.4
rigors 1.4
flushing 1.3
Spots 1.2
orthopnea 1.2
spasm 1.2
cachexia 1.2
tenesmus 1.1
snoring 1.1
stomach pain 1.1
hemoptysis 1.0
lethargy 1.0
fever of unknown origin 1.0
abdominal cramps 1.0
more...
Drug
Ancrod 9.4
Batroxobin 9.3
Hemocoagulase 9.2
Onercept 9.0
Lamifiban 8.9
Sibrafiban 8.5
Lodoxamide ethyl 8.5
Dibotin 8.0
Napsagatran 8.0
Pentastarch 8.0
Aurexis 8.0
Antithrombin III 7.7
Aggrastat 7.6
Brinase 7.6
Clinofibrate 7.5
Eptifibatide 7.4
Calciparine 7.3
Lifibrol 7.3
A.P.L. 7.2
Monteplase 7.2
Ifenprodil tartrate 7.2
Hirulog 7.1
Abciximab 7.1
Iotasul 6.9
Romurtide 6.9
OP-6 6.9
Camostat mesilate 6.8
Tranexamic Acid 6.8
Niceritrol 6.8
Sulotroban 6.7
Desmoteplase 6.7
Gabexate mesilate 6.6
Urokinase 6.6
Travase 6.6
Ciprofibrate 6.5
Suloctidil 6.5
Activase 6.5
Mononine 6.4
Bezafibrate 6.4
Alclofenac 6.3
Streptokinase 6.3
ACD-A 6.2
Hydroxyethylstarch 6.1
Pyrolite 6.0
Ridogrel 6.0
Lotrel 6.0
Benazepril hydrochloride 6.0
Trental 5.9
L-Asparaginase 5.9
Dalteparin 5.8
Bendazac 5.8
Tego 5.7
Plaquenil 5.7
Alteplase 5.6
Plaquenil 5.6
Heparin sodium 5.5
Thrombostat 5.5
Fragmin 5.5
Cilengitide 5.5
Orgaran 5.5
Protamine sulfate 5.4
Fragment 5.4
Arachidonic Acid 5.4
Aprotinin 5.4
Albumin 5.4
CS-514 5.4
Argatroban 5.4
uPA 5.3
Orgotein 5.2
Hirudoid 5.2
LMWH 5.2
Alteplase 5.2
Sodium citrate 5.2
Sodium citrate 5.2
MK-733 5.2
PFA 5.1
Lercanidipine 5.1
Plavix 5.1
Nexium 5.1
Dihydroergotamine 5.1
more...
Enzyme
atroxase 9.3
ancrod 9.1
okinaxobin II 9.0
bothropasin 8.6
fibrolase 8.4
kallikrein 14 8.2
sialidase L 7.7
bothropasin 7.6
thrombin 7.5
plasmin 7.5
thromboplastin 7.4
thrombin-activatable fibrinolysis inhibitor 7.4
clotting enzyme 7.3
matrilysin-2 7.3
complement subcomponent C1r 7.2
tissue plasminogen activator 6.9
staphopain 6.6
cathepsin O 6.5
jararhagin 6.3
cancer procoagulant 6.3
apyrase 6.1
Hageman factor 6.0
CEAS 6.0
EC 5.3.99.2 6.0
APC 5.9
Lys-gingipain 5.9
phenylpyruvate tautomerase 5.9
urokinase-type plasminogen activator 5.9
C5a peptidase 5.8
EC 2.4.2.26 5.6
C1 esterase 5.6
aureolysin 5.5
duodenase 5.4
transglutaminase 5.3
ScpA 5.2
lysyl endopeptidase 5.2
ceruloplasmin 5.1
kallikrein 4.9
serralysin 4.9
peptidylarginine deiminase 4.9
L-amino-acid oxidase 4.9
RGP 4.8
coagulation factor XIa 4.8
sortase A 4.8
asparaginase 4.6
prozyme 4.6
TAT 4.5
carboxypeptidase B 4.5
PelA 4.5
CBPP 4.4
AFR 4.4
cathepsin G 4.4
elastase 4.3
thromboxane synthase 4.2
allantoicase 4.2
creatinase 4.1
PepX 4.1
cathepsin V 4.1
proline iminopeptidase 4.0
methylenetetrahydrofolate reductase 4.0
TGT 4.0
methylenetetrahydrofolate reductase 4.0
heparinase 4.0
retinal dehydrogenase 3.9
neutrophil elastase 3.9
chymotrypsin 3.9
cathepsin X 3.8
endoproteinase Asp-N 3.8
adamalysin 3.8
tissue kallikrein 3.7
chymosin 3.7
neuropsin 3.7
N-acetylglucosaminyltransferase V 3.7
NADPH:quinone oxidoreductase 3.7
lysostaphin 3.7
prostaglandin F synthase 3.7
matrix metalloproteinase 14 3.6
proteinase A 3.6
chondroitin ABC lyase 3.6
endothiapepsin 3.5
more...
Compound
C15H22N4O4 10.0
C15H22N4O4 10.0
C15H22N4O4 10.0
C15H22N4O4 10.0
Fibrinogen 10.0
C15H22N4O4 10.0
Actol 10.0
Tripteroside 9.0
Fibrinopeptide A 9.0
FDP 8.5
2,5,8,11,14-pentaoxapentadecane 8.5
C18H24N2O5 8.5
Fibrin 8.4
Variabilin 8.0
allyl phenoxyacetate 8.0
N-Acetylimidazole 7.7
2-Hydroxy-5-nitrobenzyl bromide 7.7
5-MS 7.7
Cirsilineol 7.7
C7H8NO2 7.7
FCB 7.6
Skyrin 7.5
Benzamidine 7.5
decyl acrylate 7.5
Plasmin 7.3
Thrombin 7.2
LA 4 7.2
C5H11NO2 7.2
Quebrachitol 7.2
4-amino-2-hydroxybenzoic acid 7.2
Tirofiban 7.1
methyl hydrogen sulfate 7.0
10-undecen-1-ol 7.0
methyl hydrogen sulfate 7.0
C14H12O3 7.0
4-amino-2-hydroxybenzoic acid 7.0
AEK 7.0
2-methoxyethyl acrylate 7.0
C 80 6.7
4-benzoylbenzoic acid 6.6
isophthaloyl dichloride 6.6
6-aminohexanoic acid 6.6
6-aminohexanoic acid 6.5
Factor X 6.5
Diisopropyl fluorophosphate 6.5
Dicentrine 6.5
3-mercapto-1,2-propanediol 6.5
Ticlopidine 6.4
Coproporphyrin III 6.3
2,3-dihydro-1,4-benzodioxine 6.3
PAMBA 6.3
Tranexamic acid 6.3
TEG 6.3
PMSF 6.2
1,1'-Carbonyldiimidazole 6.2
Homocystine 6.2
C6H8O4 6.1
Z-Arg-Arg-NHMec 6.1
2,3-dinor-thromboxane 6.1
Coproporphyrin III 6.0
DIC 6.0
Ferrioxamine 6.0
Rubomycin 6.0
Norathyriol 6.0
C7H16 6.0
Sulfaquinoxaline 6.0
11-dehydro-thromboxane 5.9
Azocoll 5.9
Dioleoylphosphatidylcholine 5.9
Complement factor B 5.9
Ferene 5.8
EGT 5.7
Azocasein 5.7
MEDA 5.6
BCPC 5.6
2-naphthalenesulfonamide 5.6
Aurin 5.5
Homocysteine thiolactone 5.4
Moexipril 5.4
Argatroban 5.4
more...