Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:Q9H7B4 (
histone methyltransferase
)
1,779
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
histone methyltransferase
1779
histone
718
histone H3
488
EZH2
247
Mol
225
methyltransferase
205
G9a
174
SET
161
histone deacetylase
105
Sep
91
enhancer of zeste homolog 2
68
MLL
65
SETDB1
63
Set1
60
RNA polymerase II
56
SUV39H1
54
p53
54
DNA methyltransferase
53
Enhancer of zeste homolog 2
53
histone H4
48
more...
Disease
cancer
452
tumor
312
leukemia
115
tumorigenesis
107
breast cancer
75
carcinogenesis
58
tumor progression
51
tumor growth
48
prostate cancer
45
carcinoma
32
acute myeloid leukemia
30
multiple myeloma
29
lymphoma
27
hepatocellular carcinoma
27
HP1
25
colorectal cancer
25
lung cancer
25
B-cell lymphoma
24
melanoma
24
adenocarcinoma
22
more...
Symptom
hypotonia
8
starvation
6
exhaustion
4
dystonia
4
seizures
3
pain
3
dysarthria
2
neurological disability
2
syncope
1
Scratch
1
constipation
1
chorea
1
collapse
1
splenomegaly
1
fatigue
1
masculinization
1
cachexia
1
anorexia
1
hunger
1
nausea
1
more...
Drug
lysine
566
ROS
7
MOF
6
GEO
4
IFN-gamma
4
AMC
3
Dermatol
3
Monit
3
MAP
3
Sorafenib
2
Retinoic acid
2
ICI
2
IL-2
2
Angiotensin II
2
Gel
2
CSF
2
ABC
2
ascorbate
2
Leaf
2
DBS
2
more...
Enzyme
RNA polymerase
67
DNA methyltransferase
53
histone demethylase
50
histone acetyltransferase
47
ERK
37
demethylase
34
protein kinase
20
focal adhesion kinase
18
luciferase
18
Lys4
18
mitogen-activated protein kinase
17
proteasome
17
ATPase
12
glutathione S-transferase
11
ACS
10
PHD
9
caspase-3
8
PARP
6
phosphoinositide 3-kinase
6
cdc2
5
more...
Compound
lysine
619
DNA
413
SET
161
Dec
104
Histone
76
barium
46
arginine
39
Clin
29
adenosylmethionine
28
glucose
26
methionine
26
oxygen
24
serine
20
S-adenosylhomocysteine
15
TNF
13
ATP
13
zinc
12
cysteine
12
MDA
12
threonine
11
more...