Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:Q9BZE4 (chronic renal failure)
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Human Gene/Protein
KIAA1598 11.2
PHLP 11.2
chronic renal failure 11.2
b2 microglobulin 10.2
CSPG6 10.2
HFTC 9.2
NPH2 8.9
granulocyte inhibitory protein 8.9
nephronophthisis 4 8.9
KCNJ14 8.9
NPHP2 8.6
nephrocystin 8.6
PCPB 8.6
ARCD 8.6
claudin 16 8.5
vitamin K-dependent gamma-carboxylase 8.4
Paired box 2 8.4
NPHP3 8.3
NPH1 8.2
Musculin 8.2
GalNAc transferase 3 8.0
IQCB1 8.0
TMEM126B 8.0
NPHP1 7.9
TULP4 7.9
MOP-3 7.9
nucleolar GTPase 7.9
SYNPO 7.9
CLDN19 7.8
MTND5 7.7
MIWC 7.7
NPHP4 7.7
BENE 7.6
VAX1 7.6
INVS 7.5
LSG1 7.5
DIO-1 7.5
NPHP5 7.4
claudin-19 7.4
vasoactive intestinal peptide receptor 2 7.4
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Disease
Nodular diabetic glomerulosclerosis 11.2
Thin glomerular basement membrane disease 11.2
Aortic arteriosclerosis 11.2
Chronic proliferative glomerulonephritis 11.2
Renal failure complications 11.2
Hypercreatininemia 11.2
Peripheral and visceral atherosclerosis 11.2
Familial nephropathy 10.6
chronic renal failure 10.5
uremic pneumonitis 10.4
Carcinomatosis peritonei 10.2
Other anaemias 10.2
Uremic polyneuropathy 9.6
BOS3 9.6
Renal tubular atrophy 9.6
Colonic gangrene 9.6
Gastric angiodysplasia 9.6
Ampulla cardiomyopathy 9.6
Perforating folliculitis 9.6
Pleural calcification 9.6
Frasier Syndrome 9.6
Acute on chronic renal failure 9.6
NPHP2 9.2
Semi-starvation 9.2
MCKD2 9.2
Uremic pericarditis 9.2
Sopor 9.2
Anemia of chronic renal failure 9.2
Uremic acidosis 9.2
renoprival hypertension 9.2
Iododerma 9.2
Neuromuscular toxicity 9.2
HFTC 9.2
Pseudoporphyria 9.1
Kyrle 9.1
Reflux nephropathy 9.0
Penile gangrene 9.0
Chronic uremia 9.0
Nontoxic goiter 8.9
Normochromic normocytic anemia 8.9
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Symptom
peritoneal pain 8.9
Appetite suppression 7.9
SYMPTOMS 7.3
disturbed speech 7.2
KIDNEY 7.2
Tissue sensitivity 7.1
phosphatemia 7.0
Diaphragmatic weakness 6.9
Generalized pruritus 6.7
Portal venous gas 6.6
cold sweats 6.4
abnormal taste 6.3
asterixis 6.1
hyperosmia 6.1
oliguria 5.7
vaginal pain 5.6
koilonychia 5.6
cardiovascular impairment 5.4
General symptoms 5.3
GI irritation 5.2
polyuria 5.1
Skin symptoms 5.1
hypoproteinemia 5.0
livedo 5.0
diastolic murmurs 5.0
peau d'orange 4.7
consciousness disturbance 4.7
polydipsia 4.7
bone pain 4.5
Catch 4.5
inanition 4.4
Exercise intolerance 4.3
Macula 4.3
muscle cramps 4.2
decreased appetite 4.2
intestinal bleeding 4.1
generalized rash 4.0
prostatism 4.0
visual hallucination 4.0
nocturnal polyuria 4.0
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Drug
Ferric gluconate 11.2
Lipofen 11.2
Edetate calcium disodium 10.2
Enocitabine 10.2
Zemplar 9.2
Muzolimine 8.7
Geref 8.6
Geref 8.6
Aluminum lactate 8.4
Lanthanum carbonate 8.2
Innohep 8.1
Torasemide 7.8
Adosterol 7.6
Sevelamer 7.6
Iopentol 7.6
Aramine 7.5
Epoetin alfa 7.5
Aramine 7.4
Calcifediol 7.4
Epoetin alfa 7.3
Sevelamer carbonate 7.3
Apresoline 7.3
Kayexalate 7.2
Epoetin 7.1
Lotrel 7.1
Maxacalcitol 7.0
Darbepoetin alfa 7.0
Calcium acetate 6.8
CFDN 6.7
Rocaltrol 6.7
Deferoxamine mesylate 6.7
Ferrlecit 6.6
Venofer 6.6
Sevelamer hydrochloride 6.6
Sodium Nitroprusside 6.6
Atracurium besylate 6.6
Calcium acetate 6.5
Calciparine 6.5
PTH 6.4
Camostat mesilate 6.4
more...
Enzyme
D-2-hydroxy acid dehydrogenase 8.2
BCKA 7.7
25-hydroxyvitamin D3 1alpha-hydroxylase 7.6
stratum corneum chymotryptic enzyme 5.9
PGE2-9-ketoreductase 5.5
dimethylarginine dimethylaminohydrolase 5.5
creatininase 5.4
creatinase 5.2
oxalate oxidase 4.9
betaine-homocysteine methyltransferase 4.9
glycine amidinotransferase 4.9
adenine phosphoribosyltransferase 4.8
kynurenine 3-monooxygenase 4.6
branched-chain alpha-keto acid dehydrogenase 4.6
ACE 4.4
factor D 4.4
LMT 4.4
pantetheinase 4.4
phosphofructokinase 1 4.3
uroporphyrinogen decarboxylase 4.3
3-mercaptopyruvate sulfurtransferase 4.3
carnosinase 4.3
renin 4.2
alpha-galactosidase 4.2
isoamylase 4.0
MDP 4.0
ATP diphosphohydrolase 3.9
polyamine oxidase 3.9
sarcosine oxidase 3.8
AST 3.7
KLK7 3.7
HK2 3.7
kynureninase 3.6
Lod 3.6
CCS 3.6
aminopeptidase A 3.5
aspartase 3.5
paraoxonase 3.5
glutaryl-CoA dehydrogenase 3.4
PRT 3.4
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Compound
Ferric gluconate 11.2
DOPA sulfate 10.6
Albuterol sulfate 8.6
Methylguanidine 8.5
6-hydroxynorleucine 8.4
Homocitrulline 8.4
6-hydroxynorleucine 8.4
6-hydroxynorleucine 8.4
Carbidopa-levodopa 8.2
C4H6N2O2 7.9
CHDM 7.6
ARA-AMP 7.6
Piperacillin sodium 7.6
Allysine 7.5
Indoxyl sulfate 7.5
Homocystine 7.4
WR 1065 7.2
N(1)-methyl-2-pyridone-5-carboxamide 7.1
Guanidinosuccinic acid 7.1
C2H5NO2 7.0
4 PA 7.0
Acetohexamide 7.0
Paricalcitol 7.0
Dihydrotachysterol 6.9
Aluminum hydroxide 6.9
Carbamide peroxide 6.9
Gum arabic 6.8
Benazepril 6.7
Biloptin 6.7
Indoxyl 6.6
M 14 6.4
M 14 6.4
8-Isoprostane 6.4
Versene 6.4
Cilag 6.3
pentosidine 6.2
creatinine 6.2
Strophanthin 6.2
NHD 6.1
Methylmalonic acid 6.0
more...