Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:Q9BY76 (adipokine)
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Human Gene/Protein
ubiquitin specific protease 2 13.3
adipokine 13.3
Periostin, osteoblast specific factor 13.3
LGI3 protein 13.3
LRRC61 13.3
CTRP3 12.3
long-chain acyl-CoA synthetase 5 12.3
NRG-4 12.1
CTRP1 12.1
Meteorin-like protein 11.7
chemokine receptor-like 2 11.7
Aldehyde dehydrogenase 1 family, member A1 11.7
chemokine receptor-like 1 11.7
chemerin 11.7
chemokine-like receptor 1 11.6
Chemokine-like receptor 1 11.5
CTRP2 11.5
RARRES2 11.5
CMKLR1 11.4
Neuregulin 4 11.4
vaspin 11.4
Retinol-binding protein 4 11.4
FIAF 11.4
HC56 11.3
C1QTNF1 11.3
ccr6 11.3
ZAG 11.1
DEFB114 11.0
pre-B-cell colony-enhancing factor 10.8
Adiponectin 10.8
TMSG1 10.7
CREBL2 10.7
MYL5 10.7
APOL2 10.7
resistin 10.7
Resistin 10.6
visfatin 10.6
PBEF 10.6
glycerol-3-phosphate acyltransferase, mitochondrial 10.5
5-hydroxytryptamine (serotonin) receptor 2C 10.5
BNIP-Salpha 10.5
CTRP7 10.5
endosomal adaptor protein 10.5
ChemR23 10.4
CCRL2 10.4
WNT1 inducible signaling pathway protein 2 10.3
PAQR6 10.3
CYP19A1 protein 10.3
HCG27 10.3
Angiopoietin-like 2 10.3
adiponectin 10.2
BCDIN3D 10.1
LGI3 10.1
neuregulin 4 10.1
SYT7 10.1
TMEM207 10.1
ANGPTL4 10.1
GPR1 10.1
ADIPOR2 10.1
CTRP5 10.1
SFRP5 10.0
ANGPTL6 10.0
RAI14 10.0
P2RX5 10.0
adiponectin receptor 1 9.9
LIN7C 9.8
SLC22A17 9.8
zinc finger protein 423 9.8
LEP2 9.8
Very low density lipoprotein receptor 9.8
HL-1 9.7
apelin 9.7
LIM homeobox transcription factor 1 alpha 9.7
EXOG 9.7
CTRP6 9.7
LEP1 9.7
ZHX3 9.7
FNDC5 9.7
Adipsin 9.7
DUSP26 9.6
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Disease
Chronic skin disease 11.7
Diabetic eye disease 9.5
FGD3 9.5
Lumbar disc degeneration 9.1
Simpson-Golabi-Behmel syndrome 8.9
Adult growth hormone deficiency 8.8
Familial partial lipodystrophy 8.4
adenoma of the colon 7.9
Serous carcinoma 7.8
EBSS 7.8
Androgen excess 7.6
Gram-positive bacterial infection 7.4
generalized lipodystrophy 7.2
Idiopathic pulmonary arterial hypertension 7.1
metabolic syndrome 7.1
lipodystrophy 7.0
lipoatrophy 6.9
overnutrition 6.9
Diastolic heart failure 6.9
obesity 6.8
Prehypertension 6.8
abdominal obesity 6.8
Acute mountain sickness 6.6
moderate obesity 6.5
disorders of carbohydrate metabolism 6.4
dyslipidemia 6.4
HOA 6.3
fatty liver 6.3
alcoholic fatty liver 6.2
MCPH1 6.2
Trachea 6.2
Trachea 6.2
Trachea 6.2
Nonalcoholic fatty liver 6.2
cancer regression 6.1
Diabetic complications 6.1
Chronic hepatitis C 6.1
habitual abortion 6.0
type 2 diabetes 6.0
Diabetes and Pregnancy 6.0
glucose intolerance 6.0
APOB 5.7
SCD 5.7
ARH 5.7
fibrocystic breast disease 5.6
gestational diabetes mellitus 5.6
Pregnancy-induced hypertension 5.5
polycystic ovary syndrome 5.5
neurogenic hypertension 5.5
Alcoholic liver disease 5.5
liver infection 5.4
GSD I 5.3
hypercortisolemia 5.2
Subclinical hypothyroidism 5.2
hyperinsulinemia 5.1
Hypertrophic 5.1
cardiovascular disease 5.0
diabetic cardiomyopathy 4.9
hyperlipidemia 4.9
SDA 4.9
VISA 4.8
SMD 4.8
FBS 4.8
DBM 4.8
lipidosis 4.7
Vascular dementia 4.7
dyschondroplasia 4.7
atherosclerosis 4.7
morbid obesity 4.7
acute alcohol intoxication 4.7
FFI 4.7
hyperglycemia 4.6
EMT 4.6
CLS 4.6
metabolic disorder 4.6
CDT 4.6
anovulation 4.6
DM2 4.6
MDI 4.5
Cholangiocarcinoma 4.5
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Symptom
generalized pain 5.7
overweight 5.2
body pain 5.2
cachexia 4.9
Poor sleep 4.8
Spots 4.5
Decreased activity 4.2
Depressive symptoms 3.3
hot flashes 3.2
urinary frequency 3.2
hot flushes 3.0
hypertonia 3.0
starvation 2.4
hepatomegaly 2.4
anorexia 2.1
acute stress 2.1
hyperoxia 2.0
hunger 1.8
snoring 1.8
polyuria 1.7
memory loss 1.5
functional recovery 1.2
exhaustion 1.2
hypotonia 0.8
spasticity 0.6
angina 0.5
hypercapnia 0.4
syncope 0.1
respiratory distress 0.0
low back pain 0.0
agitation -0.3
back pain -0.3
fatigue -0.4
erythema -0.4
stigma -0.4
hypothermia -0.8
headache -0.9
weakness -0.9
analgesia -1.5
diarrhea -1.5
pain -1.5
anesthesia -2.4
Drug
Cassia seed 10.1
Metreleptin 9.9
Torcetrapib 8.1
Prolastin 7.9
Benzylamine 7.5
Rosiglitazone 7.2
NOV 7.2
Calan 7.0
Vanilla 6.2
Vinpocetine 6.1
CET 6.0
Vitamin A 5.9
APM 5.8
Olmesartan 5.6
Isoptin 5.3
Geranium 5.3
CLS 5.1
Exenatide 5.0
Rimonabant 5.0
Olive oil 4.7
Tocilizumab 4.6
Liraglutide 4.5
Epigallocatechin 4.5
Ezetimibe 4.5
Rosuvastatin 4.5
IL-1ra 4.5
DEX 4.5
Valsartan 4.4
Emodin 4.4
Troglitazone 4.2
Donepezil 4.2
Activin 4.2
Emodin 4.1
BTC 4.1
PDL 3.9
Tocopherol 3.9
Vitamin K 3.8
Camp 3.8
BH4 3.7
Pravastatin 3.6
Diurnal 3.6
EPA 3.5
Adenosine triphosphate 3.5
NVP 3.4
Angiotensin II 3.3
Luteinizing 3.3
Doxycycline 3.2
Clopidogrel 3.2
IL-11 3.2
Estrogens 3.2
Fragment 3.1
Serum albumin 3.0
Glucagon 3.0
niacin 3.0
CCL 3.0
ROS 2.9
ALA 2.8
Allergen 2.7
Heme 2.7
EE2 2.7
ADM 2.7
Gelatin 2.5
Fructose 2.4
ROC 2.4
Theophylline 2.3
uPA 2.3
DMI 2.2
ACT 2.2
G418 2.2
Glycerol 2.1
G-CSF 1.9
Bifidobacterium 1.8
Growth hormone 1.8
Growth hormone 1.7
Vitamin E 1.6
Retinoic acid 1.6
PTH 1.6
HCH 1.5
vitamin E 1.5
p75 1.4
more...
Enzyme
nicotinamide phosphoribosyltransferase 8.9
D-dopachrome tautomerase 8.9
hormone-sensitive lipase 7.1
nicotinic acid phosphoribosyltransferase 7.1
LPL 6.9
KLK7 6.8
AMPK 6.8
AMP-activated protein kinase 6.7
AMP-activated kinase 6.4
lipoprotein lipase 6.1
diacylglycerol acyltransferase 6.1
ceramidase 5.9
AMPK 5.8
TSR 5.8
phosphatidylinositol-4,5-bisphosphate 3-kinase 5.7
pregnancy-associated plasma protein-A 5.6
factor D 5.5
eEF2 kinase 5.4
thrombin-activatable fibrinolysis inhibitor 5.3
acetyl-CoA carboxylase 5.3
proteinase A 5.2
BAT 5.2
cytochrome P-450scc 5.2
cathepsin K 5.0
glycerophosphate acyltransferase 5.0
6-phosphofructo-2-kinase 4.9
neutral sphingomyelinase 4.9
paraoxonase 4.9
oxidosqualene cyclase 4.9
glycerol-3-phosphate dehydrogenase 4.8
glycerol-3-phosphate dehydrogenase 4.8
proprotein convertase 4.8
beta-hydroxybutyrate dehydrogenase 4.7
lysyl oxidase 4.6
paraoxonase 4.6
aminopeptidase A 4.6
11beta-hydroxysteroid dehydrogenase 4.6
Pla 4.5
lactonase 4.5
3beta-hydroxysteroid dehydrogenase 4.4
HMG-CoA synthase 4.4
phosphatidylinositol 3-kinase 4.4
aldehyde reductase 4.3
aldehyde reductase 4.3
aldehyde reductase 4.3
PDK1 4.2
phosphoinositide 3-kinase 4.1
mitogen-activated protein kinase 4.1
glucose-6-phosphatase 4.0
CPT 4.0
GTP cyclohydrolase I 3.9
monoacylglycerol lipase 3.9
phosphoenolpyruvate carboxykinase 3.9
phosphoenolpyruvate carboxykinase 3.8
MMP 3.8
sphingosine kinase 3.8
CEP 3.8
phosphoenolpyruvate carboxykinase 3.7
CPT 3.7
acyl-CoA synthetase 3.6
PAT 3.6
HSD 3.5
CPT 3.5
caspase-1 3.5
SPT 3.5
interstitial collagenase 3.4
PRE 3.4
DCF 3.4
IKK 3.4
CYP7A1 3.4
focal adhesion kinase 3.3
furin 3.2
renin 3.2
matrix metalloproteinase 9 3.2
CEP 3.2
NADPH oxidase 3.2
MMP-3 3.2
NADPH oxidase 3.1
matrix metalloproteinase 2 3.1
15-lipoxygenase 3.1
more...
Compound
2-acetyl-1,3-cyclopentanedione 11.3
C20H30O3 10.3
TXP 9.1
1,3-diphenyl-1,3-propanedione 9.1
1,3-diphenyl-1,3-propanedione 8.8
Harpagoside 8.7
Xylobiose 8.5
Manumycin 8.1
Dibenzoylmethane 7.9
Theaflavin 7.8
Paxilline 7.7
Tributyrin 7.6
Benzylamine 7.4
Fucoxanthin 7.3
Boldine 7.2
undecanoic acid 7.1
Bilobalide 7.1
undecanoic acid 7.1
238A 7.1
undecanoic acid 7.0
FMI 6.8
AICAR 6.8
Telmisartan 6.7
Pioglitazone 6.7
methyl stearate 6.6
Oleanolic acid 6.6
suberic acid 6.6
Candesartan cilexetil 6.5
Asiatic acid 6.4
Sulfatide 6.3
Oil Red O 6.2
Evodiamine 6.2
1,3-benzodioxole 6.2
A101 6.2
Evodiamine 6.1
APN 6.0
Oil Red O 5.9
AICAR 5.9
Vitamin A 5.9
TMF 5.9
Nobiletin 5.8
Diosgenin 5.6
Tauroursodeoxycholic acid 5.6
Chenodeoxycholic acid 5.5
Eicosapentaenoic acid 5.5
Mangiferin 5.4
Hydroxytyrosol 5.4
ASK 5.4
AET 5.4
Fisetin 5.3
Cinnamaldehyde 5.3
retinol 5.3
CLS 5.3
SAN 5.2
Atorvastatin 5.2
LY 294002 5.1
Insulin 5.1
Paeoniflorin 5.1
Chrysin 5.1
FFA 5.1
Cyclic ADP-ribose 5.0
Celastrol 4.9
celastrol 4.9
Metformin 4.9
Metformin 4.9
TNF 4.9
Puromycin 4.9
DPP 4.8
Ribose 4.8
DBM 4.8
Safranin O 4.8
DBM 4.8
TPCK 4.8
Ursolic acid 4.7
N-acetylmannosamine 4.7
PTU 4.7
Leucine 4.7
AIR 4.6
4-methoxybenzyl 4.6
Puerarin 4.6
more...