Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:Q9BY76 (adipokine)
3,147 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
adipokine 3147
insulin 1279
adiponectin 1146
leptin 941
Adiponectin 424
resistin 341
Mol 291
Leptin 264
cytokine 252
IL-6 219
visfatin 206
tumor necrosis factor 182
TNF 177
Sep 173
chemerin 162
leptin receptor 108
C-reactive protein 99
apelin 94
interleukin-6 92
peroxisome proliferator-activated receptor 87
Resistin 85
HL-1 78
AMPK 69
AMP-activated protein kinase 69
HDL 66
peroxisome proliferator-activated receptor gamma 62
plasminogen activator inhibitor-1 61
MCP-1 60
MAPK 59
vaspin 58
epididymal 58
IL-8 54
ERK1 53
gut 50
Cytokine 50
IL-10 50
TNF-alpha 48
lipoprotein lipase 47
p38 47
glycoprotein 45
vascular endothelial growth factor 43
lipopolysaccharide 43
endoplasmic reticulum 43
PI3K 43
AKT 41
chemokine 39
mTOR 39
collagen 39
JNK 38
STAT3 37
ERK 37
TLR4 34
monocyte chemoattractant protein-1 34
renin 33
ghrelin 33
IRS-1 32
ZAG 32
PPAR 32
insulin receptor 31
hormone-sensitive lipase 30
uncoupling protein 1 28
glucagon 27
CRP 26
tumor necrosis factor alpha 26
interleukin 6 26
angiotensin II 26
GLUT4 25
adiponectin receptor 1 24
LPS 23
ANGPTL4 23
glucose transporter 23
retinol-binding protein 23
phosphatidylinositol 3-kinase 23
caspase-3 23
adipsin 23
p65 22
IFN 21
aP2 21
THP 20
plasminogen activator inhibitor 20
more...
Disease
obesity 1424
diabetes 452
type 2 diabetes 369
metabolic syndrome 318
cancer 291
cardiovascular disease 207
atherosclerosis 203
hypertension 162
tumor 142
dyslipidemia 114
fatty liver 109
breast cancer 107
glucose intolerance 75
hyperglycemia 73
coronary artery disease 57
heart failure 53
carcinogenesis 52
hyperlipidemia 47
tumorigenesis 47
osteoarthritis 45
hyperinsulinemia 37
Alzheimer's disease 37
polycystic ovary syndrome 36
hepatocellular carcinoma 35
stroke 34
tumor progression 33
colorectal cancer 32
coronary heart disease 31
renal disease 31
psoriasis 30
abdominal obesity 30
rheumatoid arthritis 30
tumor growth 29
gestational diabetes mellitus 28
cirrhosis 28
lipodystrophy 28
alcoholic fatty liver 27
liver disease 26
myocardial infarction 25
osteoporosis 25
prostate cancer 24
Nonalcoholic fatty liver 24
cold 24
ischemia 22
depression 22
vascular disease 20
diabetic nephropathy 19
sepsis 18
colon cancer 18
sepsis 18
carcinoma 17
dementia 17
HIV 17
proteinuria 16
MCF 16
plaque 16
pancreatic cancer 16
malnutrition 16
systemic lupus erythematosus 15
melanoma 15
arthritis 15
liver fibrosis 14
skin disease 14
chronic liver disease 14
chronic obstructive pulmonary disease 13
type 1 diabetes 13
preeclampsia 13
overnutrition 13
asthma 13
metastases 12
chronic hepatitis 12
metabolic disorder 12
Crohn's disease 11
Simpson-Golabi-Behmel syndrome 11
autoimmune disease 11
uterus 11
infectious diseases 11
inflammatory bowel disease 11
chronic disease 11
myocardial ischemia 11
more...
Symptom
overweight 99
cachexia 17
starvation 13
pain 9
anorexia 6
fatigue 4
hepatomegaly 3
functional recovery 3
headache 3
exhaustion 3
angina 3
Depressive symptoms 2
hunger 2
weakness 2
diarrhea 2
hyperoxia 2
respiratory distress 2
acute stress 2
anesthesia 2
back pain 1
generalized pain 1
low back pain 1
erythema 1
body pain 1
urinary frequency 1
stigma 1
syncope 1
analgesia 1
hot flashes 1
hypertonia 1
spasticity 1
Spots 1
hypercapnia 1
Decreased activity 1
agitation 1
polyuria 1
snoring 1
Poor sleep 1
memory loss 1
hypotonia 1
hot flushes 1
hypothermia 1
Drug
Cardiovasc 26
Dermatol 23
Vitamin A 18
ROS 14
Rosiglitazone 12
EPA 8
lysine 5
Angiotensin II 5
vitamin E 5
Monit 5
EE2 5
ROC 4
MAP 3
niacin 3
NOV 3
Glucagon 3
IL-1ra 3
ascorbate 3
IL-2 3
Activin 3
Leaf 3
Asthma 2
Vitamin K 2
PTH 2
DNase I 2
Gel 2
lactose 2
Nephron 2
G-CSF 2
ADM 2
DEX 2
Metreleptin 2
Estrogens 2
BH4 2
Fragment 2
Dial 2
Bifidobacterium 2
Heme 2
ALA 2
Diurnal 2
CCL 1
Biopolymers 1
Prolastin 1
Rimonabant 1
CLS 1
Gelatin 1
Portal 1
Tocilizumab 1
Liraglutide 1
CTX 1
Rosuvastatin 1
Growth hormone 1
Cassia seed 1
Torcetrapib 1
IL-11 1
Spectrum 1
Glycerol 1
Epigallocatechin 1
ABC 1
Mutagen 1
Indomethacin 1
Geranium 1
Clopidogrel 1
Luteinizing 1
Donepezil 1
Fructose 1
CET 1
Olmesartan 1
Asn 1
G418 1
IFN-gamma 1
PCB 1
Emodin 1
Theophylline 1
NVP 1
Troglitazone 1
Adriamycin 1
BTC 1
Adenosine triphosphate 1
CTX 1
more...
Enzyme
mitogen-activated protein kinase 162
AMP-activated protein kinase 134
AMPK 70
AMPK 69
protein kinase 64
ERK 51
lipoprotein lipase 49
focal adhesion kinase 44
renin 33
hormone-sensitive lipase 30
phosphatidylinositol 3-kinase 23
alanine aminotransferase 20
caspase-3 19
luciferase 18
nicotinamide phosphoribosyltransferase 18
superoxide dismutase 17
protein kinase C 16
LPL 16
catalase 12
aspartate aminotransferase 12
lipase 11
collagenase 11
acetyl-CoA carboxylase 11
NADPH oxidase 10
phosphoinositide 3-kinase 10
MEK 9
NADPH oxidase 9
alkaline phosphatase 9
reverse transcriptase 8
NO synthase 8
glutathione peroxidase 7
proteasome 7
caspase-1 7
CPT 7
phosphoenolpyruvate carboxykinase 6
diacylglycerol acyltransferase 6
MMP 6
phosphoenolpyruvate carboxykinase 6
cathepsin K 6
phosphoenolpyruvate carboxykinase 6
GSK 5
adenylate cyclase 5
glycerol-3-phosphate dehydrogenase 5
glycerol-3-phosphate dehydrogenase 5
IKK 5
glucose-6-phosphate dehydrogenase 5
phosphodiesterase 5
paraoxonase 5
acetylcholinesterase 5
glucose-6-phosphatase 5
paraoxonase 5
thrombin 4
HSD 4
AMP-activated kinase 4
plasmin 4
CPT 4
peroxidase 4
trypsin 4
CPT 4
MIP 4
ACE 4
PDK1 4
lactate dehydrogenase 3
proprotein convertase 3
tissue plasminogen activator 3
citrate synthase 3
NOS 3
D-dopachrome tautomerase 3
calcineurin 3
complex I 3
acid phosphatase 3
MMP-3 3
lysyl oxidase 3
PARP 3
heme oxygenase 3
phospholipase C 3
AST 3
BAT 3
11beta-hydroxysteroid dehydrogenase 3
furin 3
more...
Compound
glucose 691
Dec 180
TNF 177
Clin 141
Insulin 96
oxygen 91
DNA 75
zinc 46
retinol 39
calcium 37
nitric oxide 35
water 30
silver 29
nicotinamide 29
aldosterone 27
serine 26
Cardiol 25
glycerol 25
phosphate 23
MDA 23
cAMP 23
THP 21
THP 20
creatinine 19
AMP 19
NAD 18
Vitamin A 18
ATP 18
sodium 17
iron 15
NAD 14
ethanol 14
vitamin D 12
cysteine 12
tyrosine 12
threonine 12
leucine 11
hydrogen 11
retinoic acid 11
acetate 11
arginine 11
Metformin 10
Metformin 10
lysine 9
AICAR 9
salt 9
Oil Red O 9
AICAR 9
urea 9
DHA 9
Ang II 9
Oil Red O 9
sulfate 8
cGMP 8
MTT 8
EPA 8
Pac 8
Pioglitazone 8
Curcumin 7
DPP 7
MEK 7
SDS 7
FFA 7
Angiotensin II 7
homocysteine 7
palmitic acid 7
DHA 6
CoA 6
GSH 6
DHA 6
GSH 6
adenylate 6
Leucine 6
ACTH 6
CO2 5
methionine 5
TNM 5
Diabetol 5
nicotinic acid 5
Dexamethasone 5
more...