Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:Q9BY76 (
adipokine
)
3,147
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
adipokine
3147
insulin
1279
adiponectin
1146
leptin
941
Adiponectin
424
resistin
341
Mol
291
Leptin
264
cytokine
252
IL-6
219
visfatin
206
tumor necrosis factor
182
TNF
177
Sep
173
chemerin
162
leptin receptor
108
C-reactive protein
99
apelin
94
interleukin-6
92
peroxisome proliferator-activated receptor
87
Resistin
85
HL-1
78
AMPK
69
AMP-activated protein kinase
69
HDL
66
peroxisome proliferator-activated receptor gamma
62
plasminogen activator inhibitor-1
61
MCP-1
60
MAPK
59
vaspin
58
epididymal
58
IL-8
54
ERK1
53
gut
50
Cytokine
50
IL-10
50
TNF-alpha
48
lipoprotein lipase
47
p38
47
glycoprotein
45
vascular endothelial growth factor
43
lipopolysaccharide
43
endoplasmic reticulum
43
PI3K
43
AKT
41
chemokine
39
mTOR
39
collagen
39
JNK
38
STAT3
37
ERK
37
TLR4
34
monocyte chemoattractant protein-1
34
renin
33
ghrelin
33
IRS-1
32
ZAG
32
PPAR
32
insulin receptor
31
hormone-sensitive lipase
30
uncoupling protein 1
28
glucagon
27
CRP
26
tumor necrosis factor alpha
26
interleukin 6
26
angiotensin II
26
GLUT4
25
adiponectin receptor 1
24
LPS
23
ANGPTL4
23
glucose transporter
23
retinol-binding protein
23
phosphatidylinositol 3-kinase
23
caspase-3
23
adipsin
23
p65
22
IFN
21
aP2
21
THP
20
plasminogen activator inhibitor
20
more...
Disease
obesity
1424
diabetes
452
type 2 diabetes
369
metabolic syndrome
318
cancer
291
cardiovascular disease
207
atherosclerosis
203
hypertension
162
tumor
142
dyslipidemia
114
fatty liver
109
breast cancer
107
glucose intolerance
75
hyperglycemia
73
coronary artery disease
57
heart failure
53
carcinogenesis
52
hyperlipidemia
47
tumorigenesis
47
osteoarthritis
45
hyperinsulinemia
37
Alzheimer's disease
37
polycystic ovary syndrome
36
hepatocellular carcinoma
35
stroke
34
tumor progression
33
colorectal cancer
32
coronary heart disease
31
renal disease
31
psoriasis
30
abdominal obesity
30
rheumatoid arthritis
30
tumor growth
29
gestational diabetes mellitus
28
cirrhosis
28
lipodystrophy
28
alcoholic fatty liver
27
liver disease
26
myocardial infarction
25
osteoporosis
25
prostate cancer
24
Nonalcoholic fatty liver
24
cold
24
ischemia
22
depression
22
vascular disease
20
diabetic nephropathy
19
sepsis
18
colon cancer
18
sepsis
18
carcinoma
17
dementia
17
HIV
17
proteinuria
16
MCF
16
plaque
16
pancreatic cancer
16
malnutrition
16
systemic lupus erythematosus
15
melanoma
15
arthritis
15
liver fibrosis
14
skin disease
14
chronic liver disease
14
chronic obstructive pulmonary disease
13
type 1 diabetes
13
preeclampsia
13
overnutrition
13
asthma
13
metastases
12
chronic hepatitis
12
metabolic disorder
12
Crohn's disease
11
Simpson-Golabi-Behmel syndrome
11
autoimmune disease
11
uterus
11
infectious diseases
11
inflammatory bowel disease
11
chronic disease
11
myocardial ischemia
11
more...
Symptom
overweight
99
cachexia
17
starvation
13
pain
9
anorexia
6
fatigue
4
hepatomegaly
3
functional recovery
3
headache
3
exhaustion
3
angina
3
Depressive symptoms
2
hunger
2
weakness
2
diarrhea
2
hyperoxia
2
respiratory distress
2
acute stress
2
anesthesia
2
back pain
1
generalized pain
1
low back pain
1
erythema
1
body pain
1
urinary frequency
1
stigma
1
syncope
1
analgesia
1
hot flashes
1
hypertonia
1
spasticity
1
Spots
1
hypercapnia
1
Decreased activity
1
agitation
1
polyuria
1
snoring
1
Poor sleep
1
memory loss
1
hypotonia
1
hot flushes
1
hypothermia
1
Drug
Cardiovasc
26
Dermatol
23
Vitamin A
18
ROS
14
Rosiglitazone
12
EPA
8
lysine
5
Angiotensin II
5
vitamin E
5
Monit
5
EE2
5
ROC
4
MAP
3
niacin
3
NOV
3
Glucagon
3
IL-1ra
3
ascorbate
3
IL-2
3
Activin
3
Leaf
3
Asthma
2
Vitamin K
2
PTH
2
DNase I
2
Gel
2
lactose
2
Nephron
2
G-CSF
2
ADM
2
DEX
2
Metreleptin
2
Estrogens
2
BH4
2
Fragment
2
Dial
2
Bifidobacterium
2
Heme
2
ALA
2
Diurnal
2
CCL
1
Biopolymers
1
Prolastin
1
Rimonabant
1
CLS
1
Gelatin
1
Portal
1
Tocilizumab
1
Liraglutide
1
CTX
1
Rosuvastatin
1
Growth hormone
1
Cassia seed
1
Torcetrapib
1
IL-11
1
Spectrum
1
Glycerol
1
Epigallocatechin
1
ABC
1
Mutagen
1
Indomethacin
1
Geranium
1
Clopidogrel
1
Luteinizing
1
Donepezil
1
Fructose
1
CET
1
Olmesartan
1
Asn
1
G418
1
IFN-gamma
1
PCB
1
Emodin
1
Theophylline
1
NVP
1
Troglitazone
1
Adriamycin
1
BTC
1
Adenosine triphosphate
1
CTX
1
more...
Enzyme
mitogen-activated protein kinase
162
AMP-activated protein kinase
134
AMPK
70
AMPK
69
protein kinase
64
ERK
51
lipoprotein lipase
49
focal adhesion kinase
44
renin
33
hormone-sensitive lipase
30
phosphatidylinositol 3-kinase
23
alanine aminotransferase
20
caspase-3
19
luciferase
18
nicotinamide phosphoribosyltransferase
18
superoxide dismutase
17
protein kinase C
16
LPL
16
catalase
12
aspartate aminotransferase
12
lipase
11
collagenase
11
acetyl-CoA carboxylase
11
NADPH oxidase
10
phosphoinositide 3-kinase
10
MEK
9
NADPH oxidase
9
alkaline phosphatase
9
reverse transcriptase
8
NO synthase
8
glutathione peroxidase
7
proteasome
7
caspase-1
7
CPT
7
phosphoenolpyruvate carboxykinase
6
diacylglycerol acyltransferase
6
MMP
6
phosphoenolpyruvate carboxykinase
6
cathepsin K
6
phosphoenolpyruvate carboxykinase
6
GSK
5
adenylate cyclase
5
glycerol-3-phosphate dehydrogenase
5
glycerol-3-phosphate dehydrogenase
5
IKK
5
glucose-6-phosphate dehydrogenase
5
phosphodiesterase
5
paraoxonase
5
acetylcholinesterase
5
glucose-6-phosphatase
5
paraoxonase
5
thrombin
4
HSD
4
AMP-activated kinase
4
plasmin
4
CPT
4
peroxidase
4
trypsin
4
CPT
4
MIP
4
ACE
4
PDK1
4
lactate dehydrogenase
3
proprotein convertase
3
tissue plasminogen activator
3
citrate synthase
3
NOS
3
D-dopachrome tautomerase
3
calcineurin
3
complex I
3
acid phosphatase
3
MMP-3
3
lysyl oxidase
3
PARP
3
heme oxygenase
3
phospholipase C
3
AST
3
BAT
3
11beta-hydroxysteroid dehydrogenase
3
furin
3
more...
Compound
glucose
691
Dec
180
TNF
177
Clin
141
Insulin
96
oxygen
91
DNA
75
zinc
46
retinol
39
calcium
37
nitric oxide
35
water
30
silver
29
nicotinamide
29
aldosterone
27
serine
26
Cardiol
25
glycerol
25
phosphate
23
MDA
23
cAMP
23
THP
21
THP
20
creatinine
19
AMP
19
NAD
18
Vitamin A
18
ATP
18
sodium
17
iron
15
NAD
14
ethanol
14
vitamin D
12
cysteine
12
tyrosine
12
threonine
12
leucine
11
hydrogen
11
retinoic acid
11
acetate
11
arginine
11
Metformin
10
Metformin
10
lysine
9
AICAR
9
salt
9
Oil Red O
9
AICAR
9
urea
9
DHA
9
Ang II
9
Oil Red O
9
sulfate
8
cGMP
8
MTT
8
EPA
8
Pac
8
Pioglitazone
8
Curcumin
7
DPP
7
MEK
7
SDS
7
FFA
7
Angiotensin II
7
homocysteine
7
palmitic acid
7
DHA
6
CoA
6
GSH
6
DHA
6
GSH
6
adenylate
6
Leucine
6
ACTH
6
CO2
5
methionine
5
TNM
5
Diabetol
5
nicotinic acid
5
Dexamethasone
5
more...