Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:Q9BY76 (
adipokine
)
3,147
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
adipokine
3147
insulin
1279
adiponectin
1146
leptin
941
Adiponectin
424
resistin
341
Mol
291
Leptin
264
cytokine
252
IL-6
219
visfatin
206
tumor necrosis factor
182
TNF
177
Sep
173
chemerin
162
leptin receptor
108
C-reactive protein
99
apelin
94
interleukin-6
92
peroxisome proliferator-activated receptor
87
Resistin
85
HL-1
78
AMP-activated protein kinase
69
AMPK
69
HDL
66
peroxisome proliferator-activated receptor gamma
62
plasminogen activator inhibitor-1
61
MCP-1
60
MAPK
59
vaspin
58
epididymal
58
IL-8
54
ERK1
53
IL-10
50
gut
50
Cytokine
50
TNF-alpha
48
p38
47
lipoprotein lipase
47
glycoprotein
45
endoplasmic reticulum
43
lipopolysaccharide
43
vascular endothelial growth factor
43
PI3K
43
AKT
41
mTOR
39
collagen
39
chemokine
39
JNK
38
STAT3
37
ERK
37
monocyte chemoattractant protein-1
34
TLR4
34
ghrelin
33
renin
33
PPAR
32
IRS-1
32
ZAG
32
insulin receptor
31
hormone-sensitive lipase
30
uncoupling protein 1
28
glucagon
27
angiotensin II
26
CRP
26
tumor necrosis factor alpha
26
interleukin 6
26
GLUT4
25
adiponectin receptor 1
24
adipsin
23
caspase-3
23
LPS
23
ANGPTL4
23
retinol-binding protein
23
phosphatidylinositol 3-kinase
23
glucose transporter
23
p65
22
IFN
21
aP2
21
plasminogen activator inhibitor
20
APJ
20
THP
20
protein kinase B
19
chemokine-like receptor 1
19
fatty acid synthase
19
CMKLR1
19
CCL2
18
hemoglobin
18
signal transducer and activator of transcription 3
18
albumin
18
insulin-like growth factor
18
AMP
18
ATP
18
growth hormone
18
angiotensinogen
17
JAK2
17
estrogen receptor
17
Fibroblast growth factor 21
17
IGF-1
17
Retinol-binding protein 4
17
VEGF
17
LPL
16
adipose triglyceride lipase
16
extracellular signal-regulated kinase
16
ADIPOR2
16
G protein-coupled receptor
16
nuclear receptor
16
adaptor protein
16
IL6
16
CD36
16
perilipin
15
aromatase
15
PKA
15
FIAF
15
APPL1
15
alanine aminotransferase
15
ROS
14
haptoglobin
14
T-cadherin
14
fibronectin
14
CTRP3
14
inducible nitric oxide synthase
14
matrix metalloproteinase
14
progranulin
14
p38 mitogen-activated protein kinase
14
IL-1
14
NAD
14
FSH
13
IRS-2
13
STAT
13
IGF1
13
monocyte chemoattractant protein
13
Lipocalin-2
13
GPR1
13
ChemR23
13
osteogenic
13
fibrinogen
13
nitric oxide synthase
12
glucocorticoid receptor
12
NGAL
12
SFRP5
12
superoxide dismutase
12
IL-18
12
fatty acid binding protein
12
p53
12
Ang II
12
PGC
12
metalloproteinase
12
CD4
12
kit
11
AdipoQ
11
interferon
11
natriuretic peptide
11
c-Jun
11
Pol
11
RANTES
11
monocyte chemotactic protein
11
prolactin
11
hepatocyte growth factor
11
osteocalcin
11
FABP4
11
more...
Disease
obesity
1424
diabetes
452
type 2 diabetes
369
metabolic syndrome
318
cancer
291
cardiovascular disease
207
atherosclerosis
203
hypertension
162
tumor
142
dyslipidemia
114
fatty liver
109
breast cancer
107
glucose intolerance
75
hyperglycemia
73
coronary artery disease
57
heart failure
53
carcinogenesis
52
tumorigenesis
47
hyperlipidemia
47
osteoarthritis
45
Alzheimer's disease
37
hyperinsulinemia
37
polycystic ovary syndrome
36
hepatocellular carcinoma
35
stroke
34
tumor progression
33
colorectal cancer
32
coronary heart disease
31
renal disease
31
psoriasis
30
abdominal obesity
30
rheumatoid arthritis
30
tumor growth
29
lipodystrophy
28
cirrhosis
28
gestational diabetes mellitus
28
alcoholic fatty liver
27
liver disease
26
osteoporosis
25
myocardial infarction
25
Nonalcoholic fatty liver
24
cold
24
prostate cancer
24
ischemia
22
depression
22
vascular disease
20
diabetic nephropathy
19
sepsis
18
colon cancer
18
sepsis
18
HIV
17
carcinoma
17
dementia
17
pancreatic cancer
16
plaque
16
MCF
16
proteinuria
16
malnutrition
16
melanoma
15
systemic lupus erythematosus
15
arthritis
15
skin disease
14
chronic liver disease
14
liver fibrosis
14
overnutrition
13
chronic obstructive pulmonary disease
13
preeclampsia
13
type 1 diabetes
13
asthma
13
metabolic disorder
12
metastases
12
chronic hepatitis
12
Simpson-Golabi-Behmel syndrome
11
inflammatory bowel disease
11
autoimmune disease
11
Crohn's disease
11
myocardial ischemia
11
obstructive sleep apnea
11
uterus
11
infectious diseases
11
chronic disease
11
mammary tumor
10
lung cancer
10
adenocarcinoma
10
renal failure
10
Best
10
wasting
10
hypercholesterolemia
10
heart disease
9
nephrotic syndrome
9
infertility
9
lipoatrophy
9
ovarian cancer
9
hyperphagia
9
anemia
9
cognitive impairment
9
Blocking
8
morbid obesity
8
arthropathy
8
colitis
8
lupus
8
adenoma
7
lupus
7
periodontitis
7
primary tumor
7
SDS
7
EMT
7
liver cancer
7
immunodeficiency
7
sickle cell disease
7
GSH
6
endometrial cancer
6
acute pancreatitis
6
aggressiveness
6
Adenovirus
6
multiple myeloma
6
retinopathy
6
vitamin D deficiency
6
ulcerative colitis
6
squamous cell carcinoma
6
Brown
6
hepatitis C
6
renal cell carcinoma
6
non-small cell lung cancer
6
SCD
6
Chronic hepatitis C
6
Cushing's syndrome
6
leukemia
6
FBS
5
ATM
5
FAS
5
insulinoma
5
atopic dermatitis
5
hypoglycemia
5
proliferative diabetic retinopathy
5
unstable angina
5
NAME
5
Syndrome
5
microalbuminuria
5
generalized lipodystrophy
5
glioma
5
chronic renal failure
5
pneumonia
5
glomerulosclerosis
5
cardiomyopathy
5
uremia
5
ventricular hypertrophy
5
hematologic malignancies
5
Pituitary
5
gastric cancer
5
liver cancer
5
acute myocardial infarction
5
hypothyroidism
5
schizophrenia
5
tumor angiogenesis
5
diabetic cardiomyopathy
5
dermatitis
4
major depressive disorder
4
Evans
4
tuberculosis
4
more...
Symptom
overweight
99
cachexia
17
starvation
13
pain
9
anorexia
6
fatigue
4
hepatomegaly
3
functional recovery
3
headache
3
exhaustion
3
angina
3
Depressive symptoms
2
hunger
2
weakness
2
diarrhea
2
hyperoxia
2
respiratory distress
2
acute stress
2
anesthesia
2
back pain
1
generalized pain
1
low back pain
1
erythema
1
body pain
1
urinary frequency
1
stigma
1
syncope
1
analgesia
1
hot flashes
1
hypertonia
1
spasticity
1
Spots
1
hypercapnia
1
Decreased activity
1
agitation
1
polyuria
1
snoring
1
Poor sleep
1
memory loss
1
hypotonia
1
hot flushes
1
hypothermia
1
Drug
Cardiovasc
26
Dermatol
23
Vitamin A
18
ROS
14
Rosiglitazone
12
EPA
8
Monit
5
EE2
5
lysine
5
vitamin E
5
Angiotensin II
5
ROC
4
IL-1ra
3
NOV
3
MAP
3
IL-2
3
ascorbate
3
Activin
3
Glucagon
3
niacin
3
Leaf
3
G-CSF
2
Vitamin K
2
PTH
2
Estrogens
2
DNase I
2
Asthma
2
lactose
2
Metreleptin
2
ALA
2
Gel
2
Nephron
2
Heme
2
BH4
2
ADM
2
Dial
2
Bifidobacterium
2
Fragment
2
DEX
2
Diurnal
2
CCL
1
Biopolymers
1
Prolastin
1
Rimonabant
1
CLS
1
Gelatin
1
Portal
1
Tocilizumab
1
Liraglutide
1
CTX
1
Rosuvastatin
1
Growth hormone
1
Cassia seed
1
Torcetrapib
1
IL-11
1
uPA
1
Epigallocatechin
1
CSF
1
PDL
1
Indomethacin
1
ABC
1
CTX
1
ACT
1
Fructose
1
Doxycycline
1
CET
1
Olmesartan
1
Luteinizing
1
Tocopherol
1
Growth hormone
1
Valsartan
1
Donepezil
1
Olive oil
1
IFN-gamma
1
PCB
1
Spectrum
1
Benzylamine
1
Glycerol
1
Isoptin
1
Mutagen
1
p75
1
Geranium
1
G418
1
Retinoic acid
1
Vitamin E
1
Clopidogrel
1
Emodin
1
Theophylline
1
NVP
1
HCH
1
Asn
1
Pravastatin
1
Emodin
1
nitroglycerin
1
Adriamycin
1
Camp
1
BTC
1
Adenosine triphosphate
1
Troglitazone
1
CTX
1
DMI
1
Allergen
1
Vinpocetine
1
APM
1
Ezetimibe
1
Vanilla
1
Serum albumin
1
Exenatide
1
Calan
1
Enzyme
mitogen-activated protein kinase
162
AMP-activated protein kinase
134
AMPK
70
AMPK
69
protein kinase
64
ERK
51
lipoprotein lipase
49
focal adhesion kinase
44
renin
33
hormone-sensitive lipase
30
phosphatidylinositol 3-kinase
23
alanine aminotransferase
20
caspase-3
19
luciferase
18
nicotinamide phosphoribosyltransferase
18
superoxide dismutase
17
protein kinase C
16
LPL
16
catalase
12
aspartate aminotransferase
12
acetyl-CoA carboxylase
11
lipase
11
collagenase
11
phosphoinositide 3-kinase
10
NADPH oxidase
10
NADPH oxidase
9
alkaline phosphatase
9
MEK
9
reverse transcriptase
8
NO synthase
8
caspase-1
7
CPT
7
proteasome
7
glutathione peroxidase
7
MMP
6
phosphoenolpyruvate carboxykinase
6
phosphoenolpyruvate carboxykinase
6
phosphoenolpyruvate carboxykinase
6
cathepsin K
6
diacylglycerol acyltransferase
6
glucose-6-phosphatase
5
glycerol-3-phosphate dehydrogenase
5
adenylate cyclase
5
phosphodiesterase
5
GSK
5
glycerol-3-phosphate dehydrogenase
5
glucose-6-phosphate dehydrogenase
5
paraoxonase
5
IKK
5
acetylcholinesterase
5
paraoxonase
5
thrombin
4
CPT
4
PDK1
4
AMP-activated kinase
4
peroxidase
4
MIP
4
plasmin
4
trypsin
4
HSD
4
CPT
4
ACE
4
BAT
3
furin
3
calcineurin
3
11beta-hydroxysteroid dehydrogenase
3
complex I
3
acid phosphatase
3
creatine kinase
3
proprotein convertase
3
phospholipase C
3
AST
3
tissue plasminogen activator
3
heme oxygenase
3
D-dopachrome tautomerase
3
PARP
3
lysyl oxidase
3
prostate-specific antigen
3
NOS
3
MMP-3
3
citrate synthase
3
lactate dehydrogenase
3
beta-galactosidase
2
RNase
2
cytochrome P-450scc
2
subtilisin
2
PRE
2
guanylate cyclase
2
3beta-hydroxysteroid dehydrogenase
2
urokinase-type plasminogen activator
2
KLK7
2
arginase
2
neutral sphingomyelinase
2
RNase
2
Pla
2
CAD
2
CAD
2
DCF
2
glyceraldehyde-3-phosphate dehydrogenase
2
aldehyde dehydrogenase
2
phospholipase A2
2
ceramidase
2
CAD
2
PKG
2
glutathione S-transferase
2
matrix metalloproteinase 9
2
matrix metalloproteinase 2
2
CD10
2
factor D
2
MAT
1
cdc2
1
alpha-glucosidase
1
lipoxygenase
1
TSR
1
tyrosine hydroxylase
1
SPT
1
ribonuclease
1
CPR
1
glyceraldehyde-3-phosphate dehydrogenase
1
tryptase
1
NQO1
1
protein phosphatase 2A
1
eEF2 kinase
1
hydrogenase
1
beta-hydroxybutyrate dehydrogenase
1
ribonuclease
1
NADPH-diaphorase
1
oxidosqualene cyclase
1
pyruvate kinase
1
diaphorase
1
21-hydroxylase
1
isocitrate dehydrogenase
1
MAT
1
pregnancy-associated plasma protein-A
1
pyruvate dehydrogenase
1
acyl-CoA synthetase
1
cathepsin D
1
DNase
1
CEP
1
glucokinase
1
proteinase A
1
15-lipoxygenase
1
alcohol dehydrogenase
1
CEP
1
isocitrate dehydrogenase
1
sphingosine kinase
1
GTP cyclohydrolase I
1
cholinesterase
1
pyruvate dehydrogenase
1
thrombin-activatable fibrinolysis inhibitor
1
acyl-CoA synthetase
1
nicotinic acid phosphoribosyltransferase
1
CYP7A1
1
AOR
1
aldehyde reductase
1
glyceraldehyde-3-phosphate dehydrogenase
1
aldehyde reductase
1
MDR
1
cathepsin L
1
aldose reductase
1
more...
Compound
glucose
691
Dec
180
TNF
177
Clin
141
Insulin
96
oxygen
91
DNA
75
zinc
46
retinol
39
calcium
37
nitric oxide
35
water
30
nicotinamide
29
silver
29
aldosterone
27
serine
26
Cardiol
25
glycerol
25
MDA
23
phosphate
23
cAMP
23
THP
21
THP
20
creatinine
19
AMP
19
ATP
18
Vitamin A
18
NAD
18
sodium
17
iron
15
ethanol
14
NAD
14
cysteine
12
vitamin D
12
threonine
12
tyrosine
12
arginine
11
hydrogen
11
retinoic acid
11
leucine
11
acetate
11
Metformin
10
Metformin
10
lysine
9
Oil Red O
9
salt
9
DHA
9
AICAR
9
Ang II
9
AICAR
9
Oil Red O
9
urea
9
sulfate
8
MTT
8
EPA
8
cGMP
8
Pac
8
Pioglitazone
8
Angiotensin II
7
DPP
7
MEK
7
FFA
7
homocysteine
7
SDS
7
palmitic acid
7
Curcumin
7
DHA
6
CoA
6
Leucine
6
ACTH
6
GSH
6
GSH
6
adenylate
6
DHA
6
alanine
5
galactose
5
nicotinic acid
5
TSH
5
Resveratrol
5
cobalt
5
Telmisartan
5
Dexamethasone
5
methionine
5
nicotinic acid
5
palmitic acid
5
H2O2
5
Vitamin D
5
nitrogen
5
PMA
5
Estradiol
5
TNM
5
Diabetol
5
Diabetol
5
CO2
5
ADP
4
ADP
4
ADP
4
Melatonin
4
CPT
4
NADPH
4
Cholesterol
4
Ile
4
nicotinic acid
4
Atorvastatin
4
nicotinic acid
4
PGE
4
CPT
4
NADPH
4
CAT
4
Quercetin
3
APN
3
Oleanolic acid
3
iodine
3
vanadium
3
asparagine
3
N-acetylcysteine
3
BNP
3
STZ
3
undecanoic acid
3
undecanoic acid
3
phosphorus
3
ASA
3
noradrenaline
3
Fucoxanthin
3
Lip
3
potassium
3
NKT
3
Glucagon
3
undecanoic acid
3
ALP
3
PEG
3
Asp
2
uridine
2
CAT
2
celastrol
2
aldehyde
2
ammonium
2
Dial
2
DEHP
2
DEX
2
2-ethylhexyl
2
vinyl
2
2-hydroxyethyl
2
Adenine
2
2-ethylhexyl
2
2-hydroxyethyl
2
BRL
2
tryptophan
2
Bisphenol A
2
NADP
2
PEG
2
2-hydroxyethyl
2
copper
2
cadmium
2
tryptophan
2
Progesterone
2
EDTA
2
Androgen
2
2-hydroxyethyl
2
butyric acid
2
more...