Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:Q99581 (
FEV
)
3,296
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
FEV
3296
COPD
284
Sep
238
PEF
91
Pseudomonas
67
IgE
64
Mol
60
C-reactive protein
52
MEF
43
cytokine
35
IL-8
34
IL-6
25
ERG
25
IL-5
24
eosinophil cationic protein
21
ATS
21
tumor necrosis factor
20
CFTR
20
EWS
20
interleukin-6
20
insulin
19
IL-10
19
CRP
19
ANOVA
19
ETV1
18
TNF
18
FLI1
17
CD4
17
MRC
17
PEA3
17
hemoglobin
16
ICS
15
CD8
14
fibrinogen
14
collagen
14
albumin
13
CAT
13
TNF-alpha
13
Pol
13
CO2
12
IL-13
12
phosphodiesterase
12
MRI
11
myeloperoxidase
11
neutrophil elastase
11
BID
10
LTB
10
GSH
10
IFN
10
EPA
9
PIF
9
FUS
9
AAT
9
cage
9
BAL
9
IL-4
9
superoxide dismutase
9
mast cell
9
lipopolysaccharide
8
lymphoid
8
EWSR1
8
Men
8
IgA
8
fused
7
Fli-1
7
BDP
7
glutathione peroxidase
7
She
6
GLI
6
vascular endothelial growth factor
6
TGF-beta
6
adiponectin
6
MMP-9
6
interleukin-4
6
DBP
6
IL-17
6
cystic fibrosis transmembrane conductance regulator
6
catalase
6
Mal
6
5-hydroxytryptamine
6
Cytokine
6
ACT
6
leptin
6
IL6
5
SBP
5
H. influenzae
5
alpha 1-antitrypsin
5
chronic renal failure
5
SP-D
5
DPI
5
San
5
ADRB2
5
tumor necrosis factor alpha
5
chemokine
5
alpha-1-antitrypsin
5
HLA
5
AGER
5
thymic stromal lymphopoietin
5
MIP
5
mist
5
CD14
5
tryptophan hydroxylase
5
elastin
5
serotonin transporter
5
caspase-3
4
BCOR
4
periostin
4
MCP-1
4
5-lipoxygenase
4
CFC
4
5-HT1A
4
AMP
4
GCS
4
MMP-2
4
CIC
4
CD99
4
GSTP1
4
ATPase
4
TLR4
4
Nkx2.2
4
interferon gamma
4
serum protein
4
IL10
4
GSTM1
4
glutathione S-transferase
4
tryptophan hydroxylase 2
4
UTR
4
IL-2
4
major histocompatibility complex
4
CD11b
4
matrix metalloproteinase
4
CD25
4
TGFB1
4
substance P
4
HDL
4
FIF
4
MUC5AC
4
CAP
4
ATP
4
ESR
3
BOS
3
ATA
3
GFR
3
alkaline phosphatase
3
sit
3
p38
3
olfactory
3
NMR
3
transforming growth factor-beta
3
SMA
3
rheumatoid factor
3
natriuretic peptide
3
PLA
3
histone deacetylase
3
granulocyte
3
protease inhibitor
3
LUM
3
surfactant protein B
3
IFN-gamma
3
alpha-1 antitrypsin
3
more...
Disease
chronic obstructive pulmonary disease
1066
asthma
875
COPD
284
cystic fibrosis
259
emphysema
187
lung disease
176
respiratory disease
65
chronic bronchitis
64
obesity
56
lung cancer
53
bronchiectasis
52
cancer
51
depression
49
diabetes
45
pneumonia
43
respiratory failure
39
eosinophilia
38
SEM
38
childhood asthma
38
cold
37
obstructive airway disease
36
Thorax
34
Thoracic
34
cardiovascular disease
33
tumor
32
bronchiolitis
31
allergic rhinitis
28
bronchospasm
27
pulmonary hypertension
26
hypertension
24
bronchitis
23
idiopathic pulmonary fibrosis
23
Bronchiolitis obliterans
23
bronchitis
23
COPD exacerbation
21
Ewing's sarcoma
21
heart failure
21
rhinitis
20
interstitial lung disease
20
ICS
19
obstructive sleep apnea
18
gastroesophageal reflux disease
18
AAT deficiency
18
stroke
17
osteoporosis
15
atherosclerosis
15
influenza
15
ERS
14
sickle cell disease
14
Bronchial hyperresponsiveness
13
pneumothorax
13
lymphangioleiomyomatosis
13
myocardial infarction
12
bronchopulmonary dysplasia
12
liver disease
11
sleep apnea
11
tuberculosis
11
chronic disease
11
GSH
10
malnutrition
10
MDI
10
pulmonary fibrosis
10
coronary heart disease
10
pancreatic insufficiency
10
metabolic syndrome
10
respiratory infection
10
silicosis
9
cirrhosis
9
FUS
9
Poland
9
cognitive impairment
9
scoliosis
9
West
9
cor pulmonale
9
muscular atrophy
8
graft-versus-host disease
8
sarcoidosis
8
systemic disease
8
myocardial ischemia
8
type 2 diabetes
7
atopic dermatitis
7
heart disease
7
pulmonary tuberculosis
7
ICC
7
vitamin D deficiency
7
coronary artery disease
7
ICC
7
Haemophilus
7
pneumoconiosis
7
hernia
7
interstitial pneumonia
7
Airway obstruction
7
HFA
7
Wright
6
rheumatoid arthritis
6
small airways disease
6
asbestosis
6
sympathomimetic
6
carcinoma
6
oral candidiasis
6
pulmonary edema
5
hay fever
5
prematurity
5
abdominal obesity
5
dyskinesia
5
MIP
5
aggression
5
non-small cell lung cancer
5
bacterial infection
5
ARF
5
metastases
5
byssinosis
5
sinusitis
5
sarcoma
5
chronic renal failure
5
Infection
5
peripheral primitive neuroectodermal tumor
5
empyema
4
myopathy
4
adenocarcinoma
4
CAP
4
aspergillosis
4
hyperglycemia
4
eczema
4
Andersen
4
leukemia
4
HIV
4
acute chest syndrome
4
connective tissue disease
4
Duchenne muscular dystrophy
4
hypersensitivity pneumonitis
4
sleep disturbances
4
infectious diseases
4
LTD
4
bronchogenic carcinoma
4
tumorigenesis
4
chronic pain
4
genetic disorder
4
FIF
4
confusion
4
lymphoma
4
arthritis
3
sepsis
3
congestive heart failure
3
major depressive disorder
3
Chlamydia
3
Toxic epidermal necrolysis
3
plaque
3
pruritus
3
portal hypertension
3
respiratory acidosis
3
primitive neuroectodermal tumor
3
virus infection
3
reactive airway disease
3
PDE
3
Exercise-induced asthma
3
polycystic ovary syndrome
3
substance abuse
3
vascular disease
3
sepsis
3
more...
Symptom
dyspnea
313
cough
127
wheezing
53
fatigue
33
pain
30
shortness of breath
25
exertional dyspnea
24
weakness
20
overweight
19
hypercapnia
17
chest tightness
17
anesthesia
16
chronic cough
16
discomfort
15
discomfort
14
hemoptysis
14
exhaustion
13
headache
12
Respiratory symptoms
11
chest pain
11
productive cough
11
analgesia
10
hyperoxia
9
tremor
8
cachexia
7
nausea
7
sleepiness
6
persistent cough
6
clubbing
5
tachypnea
5
Air trapping
4
sore throat
4
collapse
4
twitching
4
hoarseness
4
hunger
4
nocturnal cough
4
diarrhea
3
anorexia
3
Ill
3
Welt
3
chills
3
stridor
3
cyanosis
2
rhinorrhea
2
night sweats
2
respiratory distress
2
catarrh
2
back pain
2
Hudson
2
abdominal pain
2
acute pain
2
sinus congestion
2
snoring
2
Quadriceps weakness
2
orthopnea
2
Lung hyperinflation
2
nasal congestion
2
Gasping
1
rales
1
syncope
1
labored breathing
1
Rhonchi
1
dry throat
1
dizziness
1
dysuria
1
torticollis
1
seizures
1
Fluctuation
1
runny eyes
1
acidity
1
tingling
1
flushing
1
thinning
1
insomnia
1
erythema
1
heartburn
1
precordial pain
1
numbness
1
Hoover's sign
1
sneezing
1
hypocapnia
1
functional recovery
1
low back pain
1
epigastric pain
1
ENT
1
respiratory problem
1
paresis
1
spasm
1
Increased work of breathing
1
Depressive symptoms
1
nasal discharge
1
alexithymia
1
constipation
1
spasticity
1
out of breath
1
Diaphragmatic weakness
1
smokers cough
1
Nasal symptoms
1
Drug
Asthma
217
ETS
40
Cardiovasc
24
Salbutamol
19
MRC
17
ascorbate
11
Roflumilast
9
Budesonide
9
Roflumilast
9
ROC
8
ACT
6
Foradil
6
Histamine
6
vitamin E
6
Foradil
6
Foradil
6
PFT
6
lactose
5
Azithromycin
5
Omalizumab
5
Allergen
5
Ipratropium bromide
4
Nitric Oxide
4
IL-2
4
nitroglycerin
4
Ciclesonide
4
citric acid
4
Theophylline
3
Leaf
3
DNase I
3
Monit
3
Doxofylline
3
Pulmozyme
3
IFN-gamma
3
Ethane
3
lysine
3
Ventolin
3
Diurnal
3
Prograf
2
Talc
2
ampicillin
2
Albumin
2
Tacrolimus
2
Atrovent
2
MAP
2
Berotec
2
Spectrum
2
Fluticasone propionate
2
CSF
2
Becotide
2
Intal
2
caffeine
2
ABC
2
Fraction
2
DHT
2
Citric acid
2
DHT
2
Bricanyl
2
Glutathione
2
Omeprazole
2
EPA
2
Fluticasone furoate
2
Spiriva
2
Fenoterol
2
Dimethylformamide
1
Parkin
1
Syrup
1
ETA
1
GEO
1
Horizon
1
KCL
1
Ramipril
1
Wine
1
ENT
1
Ludiomil
1
Xanthium
1
Oxitropium bromide
1
Ludiomil
1
Malonaldehyde
1
Dermatol
1
Vitamin A
1
Portal
1
Glycerol
1
SF6
1
Alupent
1
Rituximab
1
Parkin
1
Helium
1
CCL
1
Orphan
1
IL-11
1
Nedocromil sodium
1
Simvastatin
1
Deflazacort
1
Oxycon
1
Rosiglitazone
1
Prednisone
1
Marimastat
1
PPA
1
Check
1
Ranitidine
1
Prednisolone
1
Solon
1
G418
1
Cefaclor
1
Alupent
1
Itraconazole
1
Serevent
1
Denufosol tetrasodium
1
Vanceril
1
Indomethacin
1
Ginseng
1
MINO
1
Fragment
1
Pirfenidone
1
Coral
1
niacin
1
PTH
1
Meptin
1
ROS
1
Forskolin
1
BH4
1
HCG
1
Coal tar
1
Aminoguanidine
1
Mepolizumab
1
Dial
1
Accolate
1
Enzyme
catalase
19
aspartate aminotransferase
13
phosphodiesterase
12
peroxidase
12
neutrophil elastase
11
ERK
10
BAL
9
superoxide dismutase
9
luciferase
7
glutathione peroxidase
7
elastase
7
collagenase
6
MIP
5
alanine aminotransferase
5
tryptophan hydroxylase
5
glutathione S-transferase
4
ATPase
4
trypsin
4
alkaline phosphatase
3
AST
3
MMP-3
3
PDE
3
complex I
3
glutathione reductase
3
CYP3A4
3
lactate dehydrogenase
3
tryptase
3
ACE
3
ACS
3
DNase
3
heme oxygenase
3
hexokinase
2
mitogen-activated protein kinase
2
phospholipase C
2
PAH
2
succinate dehydrogenase
2
MMP
2
deoxyribonuclease
2
deoxyribonuclease
2
CD10
2
gamma-glutamylcysteine synthetase
2
acetylcholinesterase
2
reverse transcriptase
2
citrate synthase
2
CYP27A1
2
chitinase
2
creatine kinase
2
pyruvate kinase
2
caspase-3
2
NO synthase
2
TSP-1
1
granzyme B
1
hyaluronidase
1
SST
1
beta-lactamase
1
GSK
1
phosphofructokinase
1
hyaluronidase
1
cathepsin K
1
monoamine oxidase
1
AMP-activated protein kinase
1
iduronate-2-sulfatase
1
isocitrate dehydrogenase
1
peroxiredoxin
1
gamma-glutamyl transpeptidase
1
LTA4 hydrolase
1
renin
1
SPT
1
prostate-specific membrane antigen
1
ADH
1
NOS
1
cholinesterase
1
SPT
1
MAP
1
CD13
1
caspase-8
1
3-hydroxyacyl-CoA dehydrogenase
1
cysteine synthase
1
NADH dehydrogenase
1
succinic dehydrogenase
1
aromatic L-amino acid decarboxylase
1
isocitrate dehydrogenase
1
hormone-sensitive lipase
1
diaphorase
1
thrombin
1
PAT
1
jararhagin
1
lipoxygenase
1
caspase-1
1
cathepsin S
1
kinesin
1
alcohol dehydrogenase
1
cytochrome oxidase
1
bromelain
1
chalcone synthase
1
phosphorylase
1
cystathionine beta-synthase
1
glucose-6-phosphate dehydrogenase
1
tissue plasminogen activator
1
NQO1
1
nicotinamide N-methyltransferase
1
3-hydroxyacyl-CoA dehydrogenase
1
MDR
1
lipase
1
protein kinase
1
Compound
Dec
255
oxygen
226
Clin
153
CO2
134
nitric oxide
129
DNA
49
nitrogen
48
bromide
43
5-HT
31
glucose
27
water
26
Salbutamol
20
TNF
18
potassium
17
creatinine
16
Formoterol
15
Methacholine
15
vitamin D
15
Pac
14
CAT
13
sodium
13
CAT
13
CAT
13
acetate
12
GSH
11
GSH
11
MDR
11
Vitamin D
10
AAT
9
His
9
BAL
9
sulfate
9
arginine
8
Gly
8
ammonia
7
HFA
7
Mannitol
7
Mannitol
7
adenylate
7
Cardiol
7
DBP
7
phosphate
7
ASA
7
PGE
6
Terbutaline
6
Histamine
6
DBP
6
6-12
6
Salmeterol
6
ECP
6
iron
6
calcium
6
ECP
6
ECP
6
toluene
6
DPI
5
Fluticasone
5
proline
5
Azithromycin
5
TDI
5
Fluticasone
5
cAMP
5
Salt
5
N-acetylcysteine
5
SVC
5
Leucovorin
4
AMP
4
CAP
4
urea
4
alanine
4
Montelukast
4
formaldehyde
4
LTC4
4
Zafirlukast
4
8-OHdG
4
LTD
4
leucine
4
Theophylline
4
silver
4
zinc
4
hydrogen
4
Fibrinogen
4
Malondialdehyde
4
CAP
4
ATP
4
benzene
4
formaldehyde
4
homocysteine
4
glutamate
4
CAM
4
isopropanol
3
Asp
3
cysteine
3
fluorine
3
lysine
3
PAP
3
ACS
3
chlorine
3
phosphocreatine
3
ACS
3
PGD2
3
barium
3
PAP
3
cadmium
3
Tobramycin
3
ethylbenzene
3
nitrate
3
ATA
3
MDA
3
PAP
3
TEM
3
ammonium
3
PLA
3
NH2
3
PAP
3
salt
3
retinol
2
Adrenal
2
MIC
2
glycerol
2
DTPA
2
Lactate
2
Cortisol
2
Prednisolone
2
glutamine
2
tyrosine
2
Insulin
2
superoxide radical
2
GSSG
2
EPA
2
Ipratropium
2
Disodium cromoglycate
2
Hemoglobin
2
MAOA
2
GABA
2
retinoic acid
2
caffeine
2
NO3
2
TET
2
phosphorus
2
serine
2
Metformin
2
iodine
2
ITP
2
PAH
2
Asbestos
2
A 1
2
GMP
2
Omeprazole
2
Styrene
2
Metformin
2
Nedocromil
2
SDS
2
Vancomycin
2
MBC
2
DHT
2
isopentenyl diphosphate
2
TET
2
PAC
2
CIT
2
more...