Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UNIPROT:Q99581 (FEV)
 3,296 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Chronic inhalation of dust impairs lung function and may cause respiratory symptoms. However, knowledge about the type of dust that can cause these problems is uncertain. Very little attention has been paid to the health of workers chronically exposed to dust raised by street sweeping without precautionary measures. Therefore, a study of lung function, oxygen saturation and symptoms among female street sweepers and their control groups in Calabar, Nigeria was carried out. Ventilatory function tests were done using 200 female street sweepers whose length of service was less than two years and 200 sex, age, weight, and height - matched external controls who were not exposed to any known air pollutant. The percentage of oxygen saturation (SPO((2)) of both the subjects and their control population was determined using a pulse oximeter. Respirable dust level in the test sites was 0.194 +/- 0.002 mu g/m3 and it was significantly higher (P < 0.001) than in control sites, which was 0.015 +/- 0.003 mu g/m3.There was no significant difference in the mean values of SPO((2))between the test and control subjects. However, there was also a significantly higher [P < 0.001] prevalence of back pain, cough, chest pain , catarrh and sneezing among the street sweepers compared to control. Lung function values, namely; FVC, FEV((1)), FEV((1)) % and PEFR were not significantly different in the two groups. Street sweeping; without precautionary measures may predispose to respiratory and non-respiratory symptoms.
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PMID:Lung function, oxygen saturation and symptoms among street sweepers in calabar-Nigeria. 1722 Sep 17

This article describes respiratory symptoms and lung function in 98 fish processing female workers employed in a fish processing plant located on the Croatian Adriatic coast and 95 matching controls. The study included chronic and acute respiratory symptoms which developed during the shifts. Lung function measurements included forced vital capacity (FVC), one-second forced expiratory volume (FEV(1)) and maximal expiratory rates at 50 % and the last 25 % (FEF(50), FEF(25)). Chronic respiratory symptoms were significantly dominant in fish processing workers compared to controls. The most common chronic symptoms were hoarseness (57.1 %), nasal catarrh (51.0 %), chronic cough (42.9 %), chronic phlegm (34.7 %), and frequent chest cold (35.7 %). Exposed smokers and nonsmokers had a similar prevalence of chronic respiratory symptoms. Acute symptoms over the work shift were high, with headache in lead (smokers: 62.5 %; nonsmokers: 56.1 %). Most of the ventilatory capacity parameters were significantly lower than predicted, FEF(25) in particular, indicating obstructive changes predominantly in the smaller airways. These findings suggest that fish processing workers are prone to developing acute and chronic respiratory symptoms as well as to lung function changes. This calls for medical and technical preventive measures to be introduced in the work environment of the fish processing plant.
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PMID:Respiratory symptoms in fish processing workers on the Adriatic coast of Croatia. 2272 2