Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UNIPROT:Q99542 (matrix metalloproteinase)
15,999 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein matrix metalloproteinase 15999 MMP-9 3202 MMP-2 2664 collagen 2332 Mol 1586 metalloproteinase 1074 Sep 1060 MMP 928 MMP-1 927 vascular endothelial growth factor 914 EPA 803 tumor necrosis factor 799 cytokine 764 MMP-3 675 TIMP-2 661 MMP9 597 MT1-MMP 550 MMP-13 527 p38 507 matrix metalloproteinase 2 489 TNF 478 collagenase 463 IL-6 461 fibronectin 454 ERK1 434 E-cadherin 377 MMP2 362 ERK 328 MAPK 325 urokinase-type plasminogen activator 325 type I collagen 323 stromelysin 306 cyclooxygenase-2 287 extracellular signal-regulated kinase 285 caspase-3 285 p65 274 AKT 272 lipopolysaccharide 272 IL-8 268 AP-1 268 MMP-7 248 inducible nitric oxide synthase 247 interleukin-6 246 MMP-8 245 tissue inhibitor of metalloproteinases 244 epidermal growth factor receptor 240 elastin 235 Bcl-2 233 TNF-alpha 220 chemokine 218 c-Jun 217 catenin 208 p53 206 TIMP 198 JNK 197 PI3K 195 vimentin 189 focal adhesion kinase 184 cyclin D1 181 epidermal growth factor 178 aggrecan 173 PLA 172 plasminogen 171 thrombospondin 167 VEGF 163 angiotensin II 161 MMP-12 161 TIMP-3 160 smooth muscle actin 160 insulin 154 type II collagen 153 proteoglycan 152 plasminogen activator inhibitor-1 148 mitogen-activated protein 148 IL-10 146 matrilysin 145 MMP14 145 phosphatidylinositol 3-kinase 140 transforming growth factor-beta 133 CD147 133 more...

Disease cancer 3393 tumor 3095 breast cancer 672 tumor growth 569 carcinoma 566 metastases 529 tumor progression 526 osteoarthritis 465 atherosclerosis 454 tumorigenesis 341 melanoma 339 stroke 328 hepatocellular carcinoma 314 lung cancer 296 arthritis 293 carcinogenesis 288 ischemia 283 hypertension 275 rheumatoid arthritis 275 plaque 274 diabetes 271 adenocarcinoma 270 glioma 249 prostate cancer 246 squamous cell carcinoma 230 MCF 203 myocardial infarction 200 colorectal cancer 187 heart failure 183 gastric cancer 182 ovarian cancer 167 liver fibrosis 160 cerebral ischemia 159 colon cancer 156 glioblastoma 147 pancreatic cancer 147 fibrosarcoma 146 asthma 142 osteosarcoma 138 chronic obstructive pulmonary disease 134 multiple sclerosis 127 abdominal aortic aneurysm 123 non-small cell lung cancer 117 cardiovascular disease 113 periodontitis 113 brain edema 113 emphysema 103 tumor angiogenesis 97 lung carcinoma 96 aggressiveness 95 Alzheimer's disease 93 obesity 90 primary tumor 88 leukemia 87 epithelial ovarian cancer 86 bladder cancer 80 HIV 79 SDS 77 pulmonary fibrosis 76 cervical cancer 75 GSH 74 renal disease 68 hyperglycemia 67 uterus 66 endometriosis 66 Evans 65 renal cell carcinoma 62 periodontal disease 62 acute myocardial infarction 60 cornea 60 brain tumor 60 preeclampsia 60 glioblastoma multiforme 59 B-cell lymphoma 59 Blocking 59 coronary artery disease 56 encephalomyelitis 56 cirrhosis 55 liver cancer 54 chondrosarcoma 54 more...

Symptom pain 108 thinning 41 skin damage 34 anesthesia 29 seizures 27 respiratory distress 25 functional recovery 23 weakness 17 erythema 16 hyperoxia 16 hypothermia 13 angina 13 dry eye 12 low back pain 11 fatigue 11 starvation 10 acidity 10 chest pain 9 diarrhea 9 arthralgia 9 cough 8 headache 8 collapse 7 dyspnea 6 back pain 6 cachexia 6 overweight 6 syncope 5 ataxia 5 Neuropathic pain 5 discomfort 5 discomfort 5 myalgia 5 abdominal pain 4 bone pain 4 exhaustion 4 skin irritation 4 stigma 4 Scratch 4 memory loss 3 constipation 3 knee pain 3 insomnia 3 pelvic pain 3 disturbed balance 3 regurgitation 3 photophobia 2 splenomegaly 2 agitation 2 nausea 2 acute stress 2 polyuria 2 sciatica 2 distraction 2 menopausal symptoms 2 leg pain 2 analgesia 2 muscle stiffness 2 paresis 1 cardiovascular problem 1 chronic cough 1 cyanosis 1 Muscle soreness 1 anorexia 1 Halo 1 HSA 1 Anoxia 1 Wind 1 dental pain 1 flushing 1 spasticity 1 nausea and vomiting 1 joint stiffness 1 rales 1 loss of balance 1 vertigo 1 orofacial pain 1 Bladder distention 1 vomiting 1 oliguria 1 more...

Drug Gelatin 194 Dermatol 180 Cardiovasc 85 lysine 75 ROS 63 Doxycycline 63 IFN-gamma 56 uPA 55 CSF 50 Monit 44 IL-2 35 MAP 33 Batimastat 31 Batimastat 31 Angiotensin II 27 Gel 27 CTX 26 Marimastat 26 CTX 25 vitamin E 25 CTX 24 Asthma 23 Asn 23 ETS 20 Ilomastat 18 ascorbate 18 CCL 16 Epigallocatechin 13 Retinoic acid 13 Ethanol 12 Simvastatin 12 p75 12 Indomethacin 12 MRC 10 IFN-beta 10 ICI 10 Emodin 9 CaCl2 9 CaCl2 9 Vitamin A 9 G418 9 Paraffin 9 Taxol 9 Nitric Oxide 9 CaCl2 9 lactose 9 Emodin 9 Heme 8 G-CSF 7 ETA 7 ROC 7 Bevacizumab 7 Imatinib 7 EE2 7 Prinomastat 7 Gefitinib 7 Rosiglitazone 7 Fluorescein 6 caffeine 6 DOXY 6 Propofol 6 Vibramycin 6 Olmesartan 6 Mutagen 6 CoCl2 6 Sorafenib 6 Ginseng 6 ACT 6 BLM 6 CoCl2 6 Oseltamivir 6 CAM 6 Arsenic trioxide 5 nitroglycerin 5 DEX 5 Cilostazol 5 Glycyrrhiza 5 SiO2 5 Bortezomib 5 Urokinase 5 more...

Enzyme collagenase 1731 mitogen-activated protein kinase 1297 MMP 1052 MMP-3 818 ERK 538 urokinase-type plasminogen activator 406 matrix metalloproteinase 2 406 matrix metalloproteinase 9 328 focal adhesion kinase 326 protein kinase 298 caspase-3 230 luciferase 206 protein kinase C 206 plasmin 201 MEK 179 tissue plasminogen activator 145 phosphatidylinositol 3-kinase 140 peroxidase 138 superoxide dismutase 138 interstitial collagenase 130 reverse transcriptase 129 elastase 126 cathepsin K 107 catalase 96 alkaline phosphatase 85 thrombin 83 NADPH oxidase 83 trypsin 82 phosphoinositide 3-kinase 75 NADPH oxidase 74 neutrophil elastase 70 furin 69 NO synthase 64 renin 63 alanine aminotransferase 62 ACS 61 stromelysin-3 54 aspartate aminotransferase 52 proteasome 51 PARP 51 ATPase 46 lactate dehydrogenase 44 IKK 44 cathepsin B 42 neutrophil collagenase 41 CD10 38 glutathione peroxidase 38 macrophage elastase 37 caspase-9 36 glutathione S-transferase 34 RNA polymerase 32 AMP-activated protein kinase 32 ACE 29 NOS 29 phospholipase C 29 chymase 28 lysyl oxidase 28 MIP 28 caspase-8 27 GSK 26 APC 25 heme oxygenase 25 xanthine oxidase 24 phosphodiesterase 24 carbonic anhydrase 24 RNase 23 RNase 23 cathepsin G 23 creatine kinase 22 TACE 22 transcriptase 22 AMPK 22 transglutaminase 22 phospholipase A2 21 neuraminidase 21 hyaluronidase 21 acid phosphatase 19 MAP 19 collagenase 3 18 proprotein convertase 18 more...

Compound Dec 1153 DNA 682 oxygen 644 Clin 502 TNF 478 acetate 351 nitric oxide 337 water 335 zinc 331 MDA 311 calcium 272 MTT 250 glucose 248 tyrosine 218 cysteine 204 serine 198 sodium 162 Collagen 159 phosphate 152 PEG 151 sulfate 130 arginine 123 lysine 120 PEG 119 THP 116 THP 116 Gly 113 leucine 113 MEK 107 Cardiol 105 hydrogen 104 alanine 101 retinoic acid 100 ethanol 98 ASA 98 methionine 86 hyaluronic acid 79 SDS 78 GSH 76 GSH 76 bromide 74 nitrogen 73 PGE 71 EDTA 69 homocysteine 69 EDTA 69 cAMP 68 Cereb 68 NH2 67 proline 66 Ang II 65 Asp 65 Doxycycline 63 ACS 61 ACS 61 ATP 61 salt 60 PMA 59 Curcumin 59 PMA 57 threonine 56 iron 54 dUTP 54 creatinine 53 Collagenase 52 iodine 51 Phe 51 galactose 50 PGE2 49 urea 48 His 44 N-acetylcysteine 42 TNM 40 Vimentin 40 pyrrolidine 36 pyrrolidine 35 aldosterone 35 Angiotensin II 33 copper 33 Ile 32 more...

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