Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:Q99542 (matrix metalloproteinase)
 15,999 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

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Human Gene/Protein
mastermind-like 3 11.0
Tissue inhibitor of metalloproteinases 4 11.0
matrix metalloproteinase 11.0
deleted in lung and esophageal cancer protein 1 11.0
bactericidal/permeability-increasing protein-like 1 11.0
IL1R2 protein 11.0
Rh family, C glycoprotein 11.0
Epilysin 10.8
epilysin 10.2
Zinc finger protein 667 10.0
Chloride intracellular channel 3 10.0
SPOCK2 protein 10.0
Polypeptide N-acetylgalactosaminyltransferase 10.0
Kinesin family member 1B 10.0
ALL1-fused gene from chromosome 1q 10.0
Reversion-inducing cysteine-rich protein with Kazal motifs 9.7
ra-a47 9.6
Ras homolog gene family, member C 9.6
MMP-28 9.6
stromelysin-3 9.6
MMP-25 9.6
PLGL 9.6
MT1-MMP 9.5
MT5-MMP 9.5
RECK protein 9.4
N-Tes 9.4
Chemokine (C-C motif) ligand 21 9.4
MT6-MMP 9.4
SNRNP25 9.4
leukolysin 9.4
FBI1 9.4
MMP-23 9.4
Rho guanine nucleotide exchange factor 7 9.4
MT4-MMP 9.4
low density lipoprotein-related protein 1 9.4
tissue inhibitor of metalloproteinases-2 9.4
metalloelastase 9.3
MPP-9 9.3
MT2-MMP 9.2
MMP25 9.2
more...
Disease
PSORS8 11.0
Renal failure and impairment 11.0
Subacromial bursitis 10.0
Corneal melt 10.0
Metaphyseal anadysplasia 10.0
endocrine system cancer 9.4
Acute quadriplegic myopathy 9.0
Papillary and follicular carcinoma 8.6
Hepatic lymphoma 8.6
ECL cell carcinoid 8.4
Acute and chronic colitis 8.2
Progressive massive fibrosis 8.2
Pathological myopia 8.2
POF3 8.2
type C thymoma 8.0
Bacterial osteomyelitis 7.8
OASF 7.8
skin cancer, basal cell 7.8
Biliary fibrosis 7.8
Recurrent corneal erosion 7.7
Rheumatic mitral valve disease 7.5
T-lymphoblastic lymphoma/leukemia 7.4
Canine cutaneous histiocytoma 7.4
Hypervitaminosis D 7.3
Lipodermatosclerosis 7.2
Chronic iron overload 7.1
Pulmonary cavitation 7.1
Tendinosis 7.0
chronic skin ulcer 7.0
Plasminogen deficiency 6.9
Invasive bladder cancer 6.9
IMD1 6.8
gastric cancer stage 6.7
Bullous keratopathy 6.7
salivary gland adenoid cystic carcinoma 6.7
metastatic follicular thyroid cancer 6.7
Amyloid arthropathy 6.7
Disseminated cancer 6.7
Critical illness myopathy 6.6
Progression of prostate cancer 6.6
more...
Symptom
Bladder distention 6.6
cardiovascular problem 6.4
skin damage 5.5
disturbed balance 4.7
Motor dysfunction 4.6
Scratch 4.3
Muscle soreness 3.8
frequent urination 3.5
catarrh 3.4
dry eye 3.2
thinning 2.9
Neuropathic pain 2.8
autodigestion 2.7
hyperoxia 2.6
Tenderness 2.4
bladder pain 2.4
loss of balance 2.1
Halo 2.1
tenesmus 2.1
swollen joints 1.9
skin irritation 1.9
sinus pressure 1.9
Anoxia 1.9
ataxic gait 1.9
functional recovery 1.8
muscle stiffness 1.7
rales 1.6
chronic back pain 1.4
chest tightness 1.4
bone pain 1.4
sciatica 1.4
respiratory distress 1.3
photophobia 1.3
arthralgia 1.3
menopausal symptoms 1.3
erythema 1.3
low back pain 1.1
knee pain 1.1
cachexia 1.1
orofacial pain 1.1
more...
Drug
Phenanthroline-1,10 11.0
Trocade 10.0
Ilomastat 9.9
Prinomastat 9.6
Marimastat 9.5
Batimastat 9.4
Batimastat 9.4
Asiasarum root 9.4
Metastat 8.2
Talabostat 8.2
Arresten 8.0
Avasimibe 8.0
DOXY 7.9
Gelatin 7.8
Cassia seed 7.8
Vibramycin 7.3
Tesaglitazar 7.1
Hpp 7.1
Citrus unshiu peel 6.9
Doxycycline 6.8
Pentosan polysulfate sodium 6.6
Ferric ammonium citrate 6.6
Satraplatin 6.2
Berberine chloride 6.2
Zaltoprofen 6.2
Nafamostat mesilate 6.0
Epigallocatechin 5.9
Olmesartan 5.8
uPA 5.7
Sesamol 5.7
Ciglitazone 5.7
MT6 5.6
Gly-Tyr-Gly 5.6
Cilomilast 5.6
Desmopressin acetate 5.5
Platelet Activating Factor 5.4
Emodin 5.2
Parecoxib 5.2
Aclarubicin 5.2
Ulinastatin 5.1
more...
Enzyme
stromelysin-3 9.7
matrilysin-2 9.6
collagenase 3 9.2
macrophage elastase 9.0
MMP 8.9
MMP-3 8.9
neutrophil collagenase 8.7
H2-proteinase 8.6
matrix metalloproteinase 2 8.4
atrolysin E 8.4
matrix metalloproteinase 9 8.2
interstitial collagenase 8.1
matrix metalloproteinase 14 8.1
aggrecanase-1 7.6
collagenase 7.6
adamalysin 7.3
atrolysin C 7.1
cathepsin K 6.8
matrix metalloproteinase 10 6.8
cathepsin V 6.6
cathepsin F 6.5
deuterolysin 6.4
fragilysin 6.3
urokinase-type plasminogen activator 6.2
sphingomyelinase D 6.2
astacin 6.2
neurolysin 6.0
matrix metalloproteinase-20 5.8
TACE 5.8
hepsin 5.8
hepsin 5.8
MT 1 5.7
cucumisin 5.7
fibrolase 5.5
lysyl oxidase 5.5
plasmin 5.5
inositol 3-kinase 5.4
furin 5.4
chymase 5.4
procollagen C-proteinase 5.3
more...
Compound
1,4-bis(phenylsulfonyl)piperazine 11.0
Reticulol 9.4
3-methylbutanamide 9.2
Hydrangenol 9.2
D-Mannuronic acid 9.0
Tricetin 8.8
benzoyl isothiocyanate 8.8
C8H10O3 8.6
methyl 3,4,5-trimethoxybenzoate 8.6
Isosakuranetin 8.6
Hecogenin acetate 8.4
Vernolide 8.4
Maclurin 8.4
CH5N 8.2
Lupulone 8.2
alpha-Chaconine 8.2
Ovatodiolide 8.1
C6H7NO 7.8
Sinulariolide 7.8
Fraxin 7.8
Cirsiliol 7.6
Ethyl ferulate 7.6
Decursin 7.6
Miltirone 7.5
4-(4-methylphenyl)-4-oxobutanoic acid 7.5
Isoorientin 7.4
Ginkgolic acid 7.4
2,4-pyrimidinediamine 7.3
Solanine 7.3
Pectolinarigenin 7.3
Ethyl gallate 7.3
Laminariaceae 7.2
Aeroplysinin-1 7.2
Pachymic acid 7.2
Tomatine 7.1
Solanine 7.1
Acacetin 7.0
Sialyl Lewis a 6.9
Solasodine 6.9
Fucosterol 6.9
more...