Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:Q99542 (
matrix metalloproteinase
)
15,999
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
matrix metalloproteinase
15999
MMP-9
3202
MMP-2
2664
collagen
2332
Mol
1586
metalloproteinase
1074
Sep
1060
MMP
928
MMP-1
927
vascular endothelial growth factor
914
EPA
803
tumor necrosis factor
799
cytokine
764
MMP-3
675
TIMP-2
661
MMP9
597
MT1-MMP
550
MMP-13
527
p38
507
matrix metalloproteinase 2
489
more...
Disease
cancer
3393
tumor
3095
breast cancer
672
tumor growth
569
carcinoma
566
metastases
529
tumor progression
526
osteoarthritis
465
atherosclerosis
454
tumorigenesis
341
melanoma
339
stroke
328
hepatocellular carcinoma
314
lung cancer
296
arthritis
293
carcinogenesis
288
ischemia
283
rheumatoid arthritis
275
hypertension
275
plaque
274
more...
Symptom
pain
108
thinning
41
skin damage
34
anesthesia
29
seizures
27
respiratory distress
25
functional recovery
23
weakness
17
hyperoxia
16
erythema
16
hypothermia
13
angina
13
dry eye
12
low back pain
11
fatigue
11
acidity
10
starvation
10
diarrhea
9
arthralgia
9
chest pain
9
more...
Drug
Gelatin
194
Dermatol
180
Cardiovasc
85
lysine
75
ROS
63
Doxycycline
63
IFN-gamma
56
uPA
55
CSF
50
Monit
44
IL-2
35
MAP
33
Batimastat
31
Batimastat
31
Gel
27
Angiotensin II
27
CTX
26
Marimastat
26
CTX
25
vitamin E
25
more...
Enzyme
collagenase
1731
mitogen-activated protein kinase
1297
MMP
1052
MMP-3
818
ERK
538
matrix metalloproteinase 2
406
urokinase-type plasminogen activator
406
matrix metalloproteinase 9
328
focal adhesion kinase
326
protein kinase
298
caspase-3
230
protein kinase C
206
luciferase
206
plasmin
201
MEK
179
tissue plasminogen activator
145
phosphatidylinositol 3-kinase
140
peroxidase
138
superoxide dismutase
138
interstitial collagenase
130
more...
Compound
Dec
1153
DNA
682
oxygen
644
Clin
502
TNF
478
acetate
351
nitric oxide
337
water
335
zinc
331
MDA
311
calcium
272
MTT
250
glucose
248
tyrosine
218
cysteine
204
serine
198
sodium
162
Collagen
159
phosphate
152
PEG
151
more...