Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:Q96S42 (nodal)
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Human Gene/Protein
TENSIN 10.4
RNF128 protein 10.4
WWC3 protein 10.4
N4BP2L1 10.4
PCDH9 protein 10.4
C6orf174 10.4
PFKP protein 10.4
nodal 10.4
gliomedin 9.5
Sperm-associated antigen 1 9.4
Ribonucleotide reductase M2 subunit 9.4
RIPPLY1 9.4
MGC45800 9.4
IFIT2 protein 9.4
SPDYC 9.4
Bral1 9.4
betaIV spectrin 9.3
MIA2 9.1
HCRP1 9.1
KIAA0471 8.9
PCDHGA3 8.9
TM4SF1 protein 8.9
ATP6V1F 8.9
PXDNL 8.9
CAPRIN2 8.9
Myeloid cell nuclear differentiation antigen 8.9
RQCD1 8.9
ACSM4 8.9
RAD54 homolog B 8.9
PABPC3 8.9
AK3L1 8.9
frizzled 5 8.6
Cx31.9 8.6
platelet-derived growth factor beta polypeptide 8.4
Glycoprotein M6B 8.4
activin A receptor, type IIB 8.4
IGHV@ 8.4
NOTO 8.4
TTC25 8.4
VAV3 protein 8.4
TWISTNB 8.4
neurofascin 8.4
Cx30.2 8.3
dynein axonemal intermediate chain 8.3
LEFTY2 8.3
promethin 8.1
BMP-3b 8.1
ARIP1 8.1
SNRPG 8.1
oxysterol binding protein-related protein 3 8.1
PSMD8 8.1
SPTBN4 8.1
ATP6V1D 8.1
CCDC151 8.1
storkhead box 1 8.1
IGHV1-8 8.1
CCDC114 8.1
WWC3 8.1
GGT6 8.1
CPS1 protein 7.9
RPP25 7.9
PKD1L1 7.9
CHPPR 7.9
Kv6.1 7.9
NudC-like protein 2 7.9
EBAF 7.9
ADAM8 protein 7.9
JPO1 7.9
ECHDC2 7.9
CRKL protein 7.7
ankyrin G 7.7
WDR18 7.6
GDF-3 7.6
SLC44A5 7.6
DR-nm23 7.6
longevity assurance gene 1 7.6
M-FABP 7.6
cTAGE-1 7.6
Zic family member 2 7.6
UBL3 7.6
more...
Disease
Palate carcinoma 10.4
Atrioventricular tachycardia 10.4
metastatic cutaneous T-cell lymphoma 10.4
Malignant esophageal stricture 10.4
Desmoplastic Melanoma 10.4
Oesophageal adenocarcinoma metastatic 10.4
Carcinoma in a polyp 10.4
Esophageal squamous cell carcinoma in situ 10.4
Stage I Seminoma 10.4
genetics of medullary thyroid cancer 10.4
AV nodal tachycardia 10.0
Concealed accessory pathway 9.9
stage IIA cervical cancer 9.9
AV nodal reentrant tachycardia 9.5
Junctional bradycardia 9.4
Testicular Lymphoma 9.4
Serous tumour of low malignant potential 9.4
Undifferentiated Carcinoma 9.4
Left ventricular hypokinesia 9.4
AV reentrant tachycardia 9.1
Wenckebach 8.9
Primary Carcinoma 8.9
ALKoma 8.9
Inguinal lymphadenopathy 8.9
Tumor ulceration 8.6
Primary cutaneous B-cell lymphoma 8.5
Gastric Lymphoma 8.4
Streptococcal pneumonia 8.4
Gastric Adenocarcinoma 8.4
Peritoneal Carcinomatosis 8.4
non-Hodgkin's lymphoma during pregnancy 8.4
Spindle cell squamous cell carcinoma 8.4
stage III laryngeal cancer 8.4
vulval neoplasm 8.4
paroxysmal supraventricular tachycardia 8.4
Sentinel node 8.3
Fascicular ventricular tachycardia 8.1
recurrent Merkel cell carcinoma 8.1
stage III renal cell carcinoma 8.1
stage IA cervical cancer 8.1
Splenic marginal zone lymphoma 8.1
Waldeyer's ring 8.1
stage B prostate cancer 8.0
stage III Hodgkin's disease 8.0
stage IIB cervical cancer 8.0
marginal zone lymphoma 8.0
stage II melanoma 8.0
extranodal lymphoma 7.9
Combined small cell carcinoma 7.9
Sinus Histiocytosis 7.9
recurrent oropharyngeal cancer 7.9
Other malignant neoplasms 7.9
T-lymphoblastic lymphoma/leukemia 7.9
Salivary gland carcinoma 7.9
APBD 7.9
Permanent junctional reciprocating tachycardia 7.9
Ectopic atrial tachycardia 7.9
Other malignant neoplasms 7.9
stage III testicular cancer 7.9
Floor of mouth 7.9
Erosive osteoarthritis 7.8
T/NK-cell lymphoma 7.8
T-zone lymphoma 7.7
Axillary metastases 7.7
Rosai-Dorfman disease 7.7
stage IV Hodgkin's disease 7.7
Cutaneous Lymphoma 7.7
Obstructive pneumonia 7.6
head neoplasm 7.6
stage I colorectal cancer 7.6
Biclonal gammopathy 7.6
Lymphocytic lymphoma 7.6
supraventricular tachycardia 7.6
Lymph node metastases 7.5
Schneiderian carcinoma 7.4
Malignant blue nevus 7.4
Bouchard's nodes 7.4
preexcitation syndrome 7.4
Junctional ectopic tachycardia 7.4
angioimmunoblastic T-cell lymphoma 7.4
more...
Symptom
lip pain 9.4
Junctional escape beats 9.4
Convulsive movements 8.9
Chest discomfort 7.4
Cardiac syncope 6.7
Shoulder stiffness 6.4
bigeminal 6.0
Other pain 5.7
Fetal bradycardia 5.4
intestinal angina 5.4
retrosternal discomfort 5.3
Todd's paralysis 5.1
presyncope 4.9
lump in the neck 4.8
pressure in the ear 4.6
Functional constipation 4.5
adenitis 4.5
aniseikonia 4.4
night sweats 4.3
syncope 4.3
syncopal episodes 4.3
Overlying 4.0
peau d'orange 3.9
dysosmia 3.9
catarrh 3.9
giddiness 3.8
giddiness 3.8
Cushingoid 3.7
Excitability 3.7
sinus pressure 3.7
nerve pain 3.7
Cushingoid 3.6
Acute urinary retention 3.5
hepatosplenomegaly 3.3
nipple discharge 3.3
non-productive cough 3.3
right lower quadrant pain 3.2
blackout 3.2
fever of unknown origin 3.1
fasciculation 3.1
otalgia 3.1
lightheadedness 3.0
nipple discharge 3.0
precordial pain 3.0
ENT 3.0
Regurgitation 2.9
exertional angina 2.9
rectal pain 2.9
impaired motor coordination 2.9
generalized pain 2.8
epigastric pain 2.8
dizziness 2.8
pedal edema 2.7
dyschezia 2.6
orthopnea 2.6
splenomegaly 2.6
hoarseness 2.5
postnasal drip 2.4
Anoxia 2.3
breath holding 2.3
dark urine 2.3
mental fatigue 2.3
flank pain 2.2
No adverse effect 2.1
testicular pain 2.0
bone pain 2.0
flushing 2.0
eye pain 1.9
mastalgia 1.9
stridor 1.8
decreased appetite 1.8
Scratch 1.8
abdominal fullness 1.8
nausea 1.8
blurred vision 1.7
chills 1.7
general problem 1.7
asthenia 1.7
hepatomegaly 1.6
dyspnea 1.6
more...
Drug
Adaprolol maleate 9.4
Imidazole Carboxamide 9.4
Quazodine 8.9
Prostascint 8.9
4',5,7-Trihydroxyisoflavone 8.4
Zeniplatin 8.1
Fostedil 8.1
Isosulfan blue 7.9
Flecainide acetate 7.7
Ferumoxtran-10 7.6
Gallium citrate Ga 67 7.6
Flecainide acetate 7.6
Draflazine 7.4
Iotasul 7.3
Zanolimumab 7.1
Toborinone 7.0
Ethmozine 7.0
Quinidine gluconate 7.0
Ethmozine 6.9
Ciclazindol 6.9
Propafenone hydrochloride 6.7
Cytomel 6.7
Indecainide 6.7
Fluvoxamine maleate 6.6
Cytomel 6.6
Tolamolol 6.6
Propafenone HCl 6.6
Aprindine 6.5
Fareston 6.4
Fareston 6.4
Norpace 6.3
Ibutilide 6.1
Cibenzoline 6.1
SUN 1165 6.1
ENX 6.1
Norpace 6.1
Visken 6.0
Aromasin 6.0
Rauwolfia serpentina 6.0
Fluvoxamine maleate 5.9
Cordarone 5.9
Trandate 5.8
Perhexiline maleate 5.7
Nicardipine hydrochloride 5.7
Ontak 5.5
Ontak 5.5
Cordarone 5.5
Pralatrexate 5.5
ProstaScint 5.4
Intron A 5.4
Intron A 5.4
Acetic Acid 5.1
Paraffin 5.0
Ascorbic Acid 4.8
Activin 4.8
Flosequinan 4.7
Ethyol 4.7
Epidoxorubicin 4.7
Digibind 4.5
Deoxyadenosine 4.5
Vena 4.5
Vena 4.5
Lugol's solution 4.5
Saha 4.4
Pimobendan 4.3
Velban 4.2
Digitalis 4.2
Amrinone 4.2
Propentofylline 4.1
MTC 4.0
Dronedarone 4.0
Bexarotene 4.0
Tirapazamine 4.0
Cilnidipine 4.0
Anagrelide 4.0
Navelbine 3.9
URF 3.9
Campath 3.9
Campath 3.9
Ferumoxytol 3.9
more...
Enzyme
kallikrein 14 7.6
kallikrein 10 6.6
deuterolysin 5.9
AO1 5.3
aspartyl aminopeptidase 5.2
prostate-specific membrane antigen 4.9
SDMT 4.7
KLK13 4.7
UDP-galactose:ceramide galactosyltransferase 4.5
GSase 4.5
Tpt1 4.4
stromelysin-3 4.4
CD10 4.2
myo-inositol oxygenase 4.1
neuropsin 4.1
isopentenyltransferase 3.9
prostate-specific antigen 3.8
AFR 3.8
GalNAc-T 3.6
granzyme B 3.6
cathepsin D 3.5
HOA 3.4
homoserine kinase 3.4
p80 3.3
macrophage elastase 3.3
thymidine phosphorylase 3.2
p-nitrophenylphosphatase 3.2
dihydropyrimidine dehydrogenase 3.1
NOS 3.1
CAO 3.0
coproporphyrinogen III oxidase 3.0
caspase-10 3.0
caspase-10 2.9
adenylosuccinate lyase 2.9
TdT 2.9
acyl carrier protein synthase 2.8
BAT 2.7
CGT 2.7
ERK 2.6
methylthioadenosine phosphorylase 2.6
STK11 2.6
NCP 2.5
dihydropyrimidine dehydrogenase 2.5
matriptase 2.5
FAST 2.5
coproporphyrinogen oxidase 2.4
matrix metalloproteinase 2 2.4
CNPase 2.4
urokinase-type plasminogen activator 2.3
PAT 2.3
FFT 2.3
sialyltransferase 2.2
HPI 2.2
sialyltransferase 2.2
sialyltransferase 2.2
arginine decarboxylase 2.2
adenosine kinase 2.2
Alternating 2.2
MsrA 2.1
orotate phosphoribosyltransferase 2.1
ACC oxidase 2.1
argininosuccinate synthetase 2.0
matriptase 1.9
legumain 1.8
biotinidase 1.8
lactate dehydrogenase 1.8
thymidylate synthase 1.8
galactocerebrosidase 1.7
PST 1.7
arginine kinase 1.7
choline kinase 1.7
CaMKII 1.6
lactic acid dehydrogenase 1.6
tryptase 1.6
PAM 1.6
indoleamine 2,3-dioxygenase 1.6
lactic acid dehydrogenase 1.5
BIS 1.5
MMP-3 1.5
TOR 1.5
more...
Compound
2-Phenylaminoadenosine 8.9
Aprindine hydrochloride 7.9
dibutylformamide 7.6
Encainide 7.5
Patent blue 7.4
Hydroquinidine 7.4
Calaxin 7.4
C6H12N2 7.3
C6H12N2 7.3
C6H12N2 7.3
C6H12N2 7.3
C6H12N2 7.3
C6H12N2 7.3
C6H12N2 7.3
C6H12N2 7.3
C6H12N2 7.3
C6H12N2 7.3
C6H12N2 7.3
C6H12N2 7.3
C6H12N2 7.3
Megestrol 7.3
C6H12N2 7.3
C6H12N2 7.3
C6H12N2 7.3
Diphemanil 7.1
5-methylisophthalic acid 7.0
IBA 6.8
C6H12N2 6.7
Propafenone 6.7
Moricizine 6.7
C6H12N2 6.5
Tiapamil 6.5
2,5-hexanediol 6.5
Flecainide 6.4
2,4-hexanedione 6.4
IBA 6.3
Disopyramide 6.3
RVK 6.3
BAP 6.3
CNCC 6.2
Ibutilide 6.2
Thiamine triphosphate 6.1
Thiamine triphosphate 6.1
1H-imidazole-4,5-dicarboxylic acid 6.0
NFN 5.9
TNM 5.9
Clofilium 5.8
Dofetilide 5.7
5-aminoisophthalic acid 5.7
IVE 5.7
DFS 5.6
SAN 5.5
Velban 5.5
2-hydroxy-4-methoxybenzaldehyde 5.5
E-4031 5.5
octacosanoic acid 5.4
Bepridil 5.3
Prenalterol 5.3
Gallopamil 5.3
Procainamide 5.3
Reticulin 5.3
Sotalol 5.2
diethylformamide 5.2
Betaxolol 5.2
C8H4O4 5.1
Ajmaline 5.1
C8H4O4 5.1
Mechlorethamine 5.0
6-hydroxynicotinic acid 5.0
Bromelia 5.0
C3H7NO 5.0
C3H7NO 5.0
PCNU 5.0
C3H7NO 4.9
Diltiazem 4.9
Diltiazem 4.9
Tocainide 4.9
Nafoxidine 4.9
Verapamil 4.8
Mexiletine 4.8
more...