Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:Q96S42 (
nodal
)
22,877
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The epithelioid variant of malignant peripheral nerve sheath tumours is a rare histological entity, and the occurrence of a malignant peripheral nerve sheath tumour in the skull base is even more unusual. We report a case of a 52-year-old man who presented with reduced hearing in the left ear,
giddiness
and left-sided facial weakness of short duration. He was a known hypertensive. On examination, left-sided 7th to 12th cranial nerve palsies were noted. Computed tomography (CT) and brain magnetic resonance imaging (MRI) were reported as an ill-defined heterogeneously enhancing mass left skull base suggestive of chondrosarcoma. Left tympanotomy and biopsy of the lesion were carried out. On light microscopy and immunohistochemical examination of the biopsy, a diagnosis of epithelioid malignant peripheral nerve sheath tumour was established. The patient underwent left extended modified radical mastoidectomy and selective neck dissection. Histopathological study of the resected surgical specimen confirmed left-sided extensive tumour involvement of skull base structures, as well as neck
nodal
metastases.
...
PMID:Widely infiltrating epithelioid malignant peripheral nerve sheath tumour of skull base. 2398 83
A 60-year-old female with triple negative breast cancer, postsurgery, neoadjuvant chemotherapy and radiotherapy, on follow-up had facial puffiness and
giddiness
.
18
F-fluorodeoxyglucose positron emission tomography/computed tomography (
18
F-FDG PET/CT) done for suspected recurrence evaluation revealed a large tumor thrombus (TT) in superior vena cava (SVC) with radiological evidence of SVC obstruction.
18
F-FDG PET/CT also showed evidence of FDG avid brain metastases, lymph
nodal
metastases, and metastatic soft tissue deposits. This case of unusually large TT in SVC detected on
18
F-FDG PET/CT highlights the ability of
18
F-FDG PET/CT to identify TT and clearly demonstrate the pattern of disease in suspected recurrence in triple negative breast cancer patients.
...
PMID:Case of Carcinoma Breast with Unusually Large Tumor Thrombus in Superior Vena Cava Detected on
18
F-Fluorodeoxyglucose Positron Emission Tomography Computed Tomography Scan. 2914 67
