Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:Q92565 (GFR)
 4,179 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
PKDR 12.9
GFR 12.9
FAM47E 12.9
KIAA0846 11.9
GDNF family receptor alpha 2 10.9
MR-GEF 10.3
GDNFR 10.1
RVR 10.1
GDNFR-alpha 9.7
GFRA3 9.6
persephin 9.5
RA-GEF 9.4
FJHN 9.4
phosphatonin 9.2
cyclin M 9.2
RET tyrosine kinase receptor 9.1
GRP3 9.1
PDZ-GEF1 9.1
SLC11 9.1
GIPC2 9.1
CNI 9.0
UAGT 9.0
neurturin 8.9
GFRAL 8.7
claudin 16 8.6
NPT2 8.6
ZNF652 8.6
MACS2 8.6
Neurturin 8.5
rap1GAP 8.5
GDNF family receptor alpha 1 8.5
ERBP 8.5
guanine nucleotide exchange factor for Rap1 8.4
BAZ2A 8.4
Tumor endothelial marker 7 8.3
peptide transporter 2 8.3
cystatin C 8.2
carboxypeptidase B 8.2
CalDAG-GEFI 8.2
upregulated in kidney 8.1
SLC34A1 8.1
Tonicity-responsive enhancer binding protein 8.0
artemin 8.0
glial cell derived neurotrophic factor 7.9
beta1,3-galactosyltransferase 7.8
cAMP-GEFII 7.8
AP17 7.7
ubiquitin D 7.7
KAP3 7.6
CLDN18 7.6
Beta-2-microglobulin 7.5
bumetanide-sensitive Na-K-2Cl cotransporter 7.5
EPI 7.5
SLC5A2 7.5
NAGA 7.5
RIFLE 7.5
SRL 7.4
PAH 7.4
FGF23 7.3
APOL1 7.3
NIDD 7.3
AMBP 7.2
secreted frizzled-related protein 4 7.2
calcineurin inhibitor 7.2
glial cell line-derived neurotrophic factor 7.2
KNG1 7.2
RNR2 7.2
SLC14A1 7.2
CP-2 7.1
haptoglobin-related protein 7.1
SNM1B 7.1
NAG 7.1
PRA 7.1
FSGS 7.1
TRPC3 protein 7.0
GDNF 7.0
CUBN 7.0
apolipoprotein L1 7.0
TCF2 7.0
ROBO2 6.9
more...
Disease
Tuberculous pyelonephritis 12.9
Moderate hydronephrosis 12.9
Hypersomatotropism 11.3
CRCL 11.3
Segmental glomerulosclerosis 10.6
Distal RTA 10.3
Chronic hyperventilation 10.1
Armanni-Ebstein lesion 9.9
Acquired disease 9.9
glycinuria 9.9
SPD1 9.9
Acute respiratory alkalosis 9.6
FJHN 9.4
Myoglobinuric acute renal failure 9.3
Unilateral renal artery stenosis 9.2
gouty nephropathy 8.8
acetonemia 8.6
Myeloma cast nephropathy 8.6
proteinuria in pregnancy 8.6
Idiopathic hypercalciuria 8.5
Paroxysmal cold hemoglobinuria 8.4
Acute respiratory distress 8.4
Bilateral hydronephrosis 8.3
phosphaturia 8.2
Parathyroid gland 8.2
Parathyroid gland 8.2
Parathyroid gland 8.2
Nodular glomerulosclerosis 8.1
Chronic kidney disease (CKD) 7.9
antidiuresis 7.9
EPV 7.9
nephroptosis 7.9
renal glycosuria 7.9
Proteinuria 7.8
hyperchloremia 7.8
Interstitial fibrosis 7.7
oxalosis 7.7
Chronic pyelonephritis 7.6
Hyponatremic 7.6
microalbuminuria 7.6
EPI 7.6
TINU 7.6
hyporeninemic hypoaldosteronism 7.6
Neonatal hyperbilirubinemia 7.5
Reflux nephropathy 7.4
Late pregnancy 7.4
Chronic anemia 7.4
chronic renal insufficiency 7.3
Nephrogenic systemic fibrosis 7.3
SACS 7.2
kidney hypertrophy 7.2
Pseudohypoaldosteronism 7.2
Hereditary tyrosinemia type I 7.1
nephrosclerosis 7.1
primary hyperoxaluria 7.1
hypercalciuria 7.1
proteinuria 7.1
Imerslund 7.0
Posterior urethral valves 7.0
Hypertensive crisis 7.0
uricosuria 7.0
Coronary artery calcification 7.0
renal insufficiency 6.9
diabetic nephropathy 6.9
aHUS 6.9
renal impairment 6.9
chronic renal failure 6.8
Severe malnutrition 6.8
aminoaciduria 6.8
renal disease 6.7
varicose ulcer 6.7
Congenital nephrotic syndrome 6.7
Goldblatt 6.7
renal ischemia 6.7
Distal renal tubular acidosis 6.7
glomerulosclerosis 6.6
Tumor-induced osteomalacia 6.6
glomerulitis 6.6
hyperphosphatemia 6.6
Laurence-Moon-Biedl syndrome 6.6
more...
Symptom
phosphatemia 8.4
unable to sleep 8.4
GI irritation 6.9
Macula 6.0
polyuria 5.7
leg cramps 5.7
oliguria 5.6
hypalgesia 5.4
Lower urinary tract symptoms 5.3
inanition 5.1
disturbed balance 5.1
Catch 4.9
dark urine 4.8
clubbing 4.1
sinus pressure 3.8
enuresis 3.8
ketonuria 3.8
hypoproteinemia 3.7
polydipsia 3.4
chronic back pain 3.3
bone pain 3.3
renal colic 3.2
livedo 3.2
emaciation 2.8
cachexia 2.8
nasal congestion 2.7
pallor 2.6
myalgia 2.5
overweight 2.5
physical appearance 2.3
colic 2.3
hypocapnia 2.2
leg pain 1.9
flank pain 1.8
bradykinesia 1.7
arthralgia 1.7
dysuria 1.6
dry eye 1.5
hypercapnia 1.5
anesthesia 1.5
HSA 1.3
flushing 1.3
dizziness 1.2
exertional dyspnea 1.2
vomiting 1.1
acidity 1.0
apathy 0.9
collapse 0.9
regurgitation 0.9
diarrhea 0.9
weakness 0.9
functional recovery 0.8
acute stress 0.7
wheezing 0.7
nausea and vomiting 0.7
respiratory distress 0.6
paresthesia 0.6
low back pain 0.6
constipation 0.6
shortness of breath 0.5
angina 0.5
Ill 0.4
thinning 0.4
hunger 0.4
lethargy 0.4
back pain 0.3
sleepiness 0.3
tinnitus 0.2
anorexia 0.1
starvation -0.1
hypothermia -0.2
splenomegaly -0.4
fatigue -0.4
abdominal pain -0.4
discomfort -0.6
headache -0.6
nausea -0.6
pain -0.6
cough -0.6
discomfort -0.7
more...
Drug
Lemildipine 11.9
Carbetimer 9.6
Fabrazyme 9.5
Belatacept 9.4
Doca 9.0
CGS 13080 8.8
Amaryl 8.6
Bendrofluazide 8.5
Xipamide 8.3
Iopentol 8.3
Cardura 8.2
Cardura 8.2
Metolazone 7.9
Lescol 7.8
EPI 7.6
Kayexalate 7.6
Ramipril 7.6
Lescol 7.5
Norvasc 7.5
Arfonad 7.4
Paraplatin 7.3
Epoetin beta 7.3
Piretanide 7.2
Potassium citrate 7.2
Tolvaptan 7.1
GRF 7.1
Pentothal 7.1
Ioversol 7.0
Elvitegravir 7.0
Folic Acid 6.9
Amlodipine besylate 6.9
Amoxapine 6.8
PTH 6.8
DMSA 6.5
Omniscan 6.5
Acetic Acid 6.5
Iohexol 6.5
Tenofovir disoproxil fumarate 6.5
Rasburicase 6.5
Valganciclovir 6.4
Felodipine 6.4
Torasemide 6.2
Lacidipine 6.2
Exenatide 6.2
Basiliximab 6.1
Basiliximab 6.1
Ketorolac tromethamine 6.1
Lacidipine 5.9
Nesiritide 5.9
Chlorothiazide 5.9
Neoral 5.9
NAG 5.8
Cilazapril 5.8
Omniscan 5.8
Everolimus 5.8
Bumetanide 5.8
Bosentan 5.8
Bosentan 5.8
Ibandronate 5.7
Tacrolimus 5.7
Captopril 5.7
Corn oil 5.6
NLF 5.6
Xeloda 5.6
Nephron 5.6
Valsartan 5.6
Perindopril 5.5
Iodixanol 5.5
2-Methoxyestradiol 5.5
Dexrazoxane 5.5
Mycophenolic acid 5.5
Eculizumab 5.4
Inderal 5.4
Misoprostol 5.4
Denosumab 5.4
Daclizumab 5.4
Fenoldopam 5.3
DDAVP 5.3
DDAVP 5.3
Cinacalcet 5.2
more...
Enzyme
glycine N-acyltransferase 7.9
PAH 7.4
PRA 7.0
ketohexokinase 6.2
PHT 5.9
ADH 5.8
fumarylacetoacetate hydrolase 5.7
renin 5.7
STK 5.7
dimethylarginine dimethylaminohydrolase 5.6
NAO 5.4
thromboxane synthase 5.3
ACE 5.2
PRT 5.1
MAP 5.0
alanine aminopeptidase 5.0
H,K-ATPase 4.7
LIS 4.6
VOR 4.6
alpha-galactosidase 4.5
proteinase-3 4.5
fructokinase 4.4
prostacyclin synthase 4.3
AGT 4.3
kallikrein 4.2
succinyl-CoA synthetase 4.2
aminopeptidase A 4.2
SPT 3.8
dipeptidyl peptidase IV 3.8
alcohol dehydrogenase 3.7
MTD 3.7
prostaglandin synthetase 3.6
endothelin-converting enzyme 3.6
NO synthase 3.5
AST 3.5
GCA 3.4
NOS 3.4
calcineurin 3.3
aldose reductase 3.2
12-lipoxygenase 3.1
CD13 3.1
SPT 3.1
carbonic anhydrase 3.0
BIS 3.0
alkaline phosphatase 2.9
gamma-glutamyl transpeptidase 2.9
SCS 2.9
nucleotidase 2.9
guanylate cyclase 2.8
TSA 2.7
tissue kallikrein 2.6
11beta-hydroxysteroid dehydrogenase 2.6
BMT 2.5
MDP 2.5
phosphoglucomutase 2.5
heme oxygenase 2.4
CAD 2.4
transpeptidase 2.4
CAD 2.4
CAD 2.3
sialyltransferase 2.3
sialyltransferase 2.3
sialyltransferase 2.3
5'-nucleotidase 2.3
PTA 2.2
hexosaminidase 2.1
PDE 2.0
cathepsin K 2.0
PAM 2.0
TdT 2.0
glutaminase 2.0
lysozyme 2.0
DCF 2.0
ATPase 1.9
aspartate aminotransferase 1.8
lipoxygenase 1.8
citrate synthase 1.8
phosphoenolpyruvate carboxykinase 1.7
ERK 1.7
adenylate cyclase 1.7
more...
Compound
2-Bromoethylamine hydrobromide 10.3
2-Bromoethylamine hydrobromide 10.3
5-Methoxytryptophan 10.3
Sulbenicillin 9.6
Ferrioxamine 8.8
8-iso-PGE2 8.6
Cefonicid 8.6
Methylcitric acid 8.4
TDGA 8.3
Inulin 8.2
Inactin 8.2
BVE 8.2
Tiludronate 8.0
Cefazolin sodium 7.9
Trimethaphan 7.9
Quinapril 7.9
N-acetylalanine 7.8
2-pyrazinecarboxylic acid 7.7
hippurate 7.5
Hippuran 7.5
N'-methylnicotinamide 7.4
PAH 7.4
T 12 7.1
Guanabenz 7.0
creatinine 7.0
N-acetylalanine 6.9
Penbutolol 6.9
DPPD 6.9
3-quinolinecarboxylic acid 6.8
Benazepril 6.8
PD 5 6.7
Fosinopril 6.7
DTPA 6.6
Candesartan 6.6
Enalapril 6.6
Estramustine 6.3
Sodium lactate 6.3
Nitro-L-arginine 6.3
Thiazide 6.2
Steviol 6.2
Netilmicin 6.2
uroporphyrin I 6.2
Fleroxacin 6.2
FUR 6.2
Paricalcitol 6.1
2,4-DP 6.1
SP 1 6.1
Diamminedichloroplatinum 6.0
Tolazoline 6.0
PHT 5.9
Meglumine 5.9
N-methylnicotinamide 5.8
Nitrendipine 5.7
Meclofenamate 5.6
Tempol 5.6
Cyclosporine 5.6
Ajmaline 5.6
DOA 5.6
20-HETE 5.6
Telmisartan 5.5
2-Methoxyestradiol 5.5
Fenoldopam 5.4
CBDCA 5.4
CBDCA 5.4
M 2 5.4
Barbiturate 5.3
aldosterone 5.3
DOCA 5.3
CNA 5.3
Pentoxifylline 5.2
Losartan 5.2
Eplerenone 5.2
CAN 5.1
11,12-EET 5.1
Gb3 5.1
TIF 5.1
TXA2 5.0
Parthenolide 5.0
Uric acid 5.0
Indinavir 5.0
more...