Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:Q92565 (GFR)
 4,179 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
PKDR 12.9
GFR 12.9
FAM47E 12.9
KIAA0846 11.9
GDNF family receptor alpha 2 10.9
MR-GEF 10.3
GDNFR 10.1
RVR 10.1
GDNFR-alpha 9.7
GFRA3 9.6
persephin 9.5
FJHN 9.4
RA-GEF 9.4
phosphatonin 9.2
cyclin M 9.2
RET tyrosine kinase receptor 9.1
GRP3 9.1
GIPC2 9.1
SLC11 9.1
PDZ-GEF1 9.1
CNI 9.0
UAGT 9.0
neurturin 8.9
GFRAL 8.7
claudin 16 8.6
ZNF652 8.6
MACS2 8.6
NPT2 8.6
Neurturin 8.5
GDNF family receptor alpha 1 8.5
rap1GAP 8.5
ERBP 8.5
guanine nucleotide exchange factor for Rap1 8.4
BAZ2A 8.4
Tumor endothelial marker 7 8.3
peptide transporter 2 8.3
cystatin C 8.2
carboxypeptidase B 8.2
CalDAG-GEFI 8.2
upregulated in kidney 8.1
SLC34A1 8.1
Tonicity-responsive enhancer binding protein 8.0
artemin 8.0
glial cell derived neurotrophic factor 7.9
beta1,3-galactosyltransferase 7.8
cAMP-GEFII 7.8
AP17 7.7
ubiquitin D 7.7
KAP3 7.6
CLDN18 7.6
Beta-2-microglobulin 7.5
bumetanide-sensitive Na-K-2Cl cotransporter 7.5
EPI 7.5
SLC5A2 7.5
NAGA 7.5
RIFLE 7.5
SRL 7.4
PAH 7.4
FGF23 7.3
APOL1 7.3
NIDD 7.3
AMBP 7.2
secreted frizzled-related protein 4 7.2
calcineurin inhibitor 7.2
glial cell line-derived neurotrophic factor 7.2
KNG1 7.2
RNR2 7.2
SLC14A1 7.2
CP-2 7.1
haptoglobin-related protein 7.1
SNM1B 7.1
NAG 7.1
PRA 7.1
FSGS 7.1
TRPC3 protein 7.0
GDNF 7.0
CUBN 7.0
apolipoprotein L1 7.0
TCF2 7.0
ROBO2 6.9
ARPKD 6.9
GAS1 6.9
proximal tubule 6.9
CA8 6.9
PTH 6.8
Guanylyl cyclase 6.7
PTCH2 6.7
SACS 6.7
NGAL 6.7
LADA 6.7
AGTR2 6.7
PODXL 6.7
aquaporin 2 6.7
NHE4 6.7
CA12 6.7
APR 6.7
RAPA 6.6
NP3 6.6
Rhes 6.6
SP-10 6.6
EVL 6.6
Tph 6.6
chronic renal failure 6.6
AHSG 6.6
sorting nexin 9 6.6
AGER 6.6
ret 6.5
Endothelin-3 6.5
JAK-2 6.5
UII 6.5
FHH 6.5
signal transducer and activator of transcription 2 6.5
C3G 6.5
Na(+)/H(+) exchanger 3 6.5
nitric oxide synthase 1 6.5
LPAR1 6.5
RET protein 6.4
neutrophil gelatinase-associated lipocalin 6.4
LVM 6.4
high affinity) 6.4
Apolipoprotein L1 6.4
UT-A2 6.4
PHEX 6.4
GRP1 6.4
Claudin-16 6.3
organic cation transporter 2 6.3
SLC22A2 6.3
EVC 6.3
hOCT2 6.2
DDAH 6.2
SERPING1 6.2
alanine-glyoxylate aminotransferase 6.2
mPGES-2 6.2
P2X4R 6.2
MEN2A 6.2
KCNMA1 6.2
beta-2-microglobulin 6.1
renalase 6.1
SGLT2 6.1
ret proto-oncogene 6.1
HEMO 6.1
RET 6.1
erbB-3 6.1
sodium/hydrogen exchanger 6.0
MATE2-K 6.0
EPAC 6.0
component D 6.0
alpha-galactosidase A 6.0
natriuretic peptide receptor A 6.0
IDDM 6.0
HUMAN 6.0
NHE-3 6.0
NIF 6.0
LRP2 5.9
parathyroid hormone 5.9
Na/H antiporter 5.9
transferin 5.9
RET proto-oncogene 5.9
Angiotensin II receptor 5.9
TXL 5.9
more...
Disease
Tuberculous pyelonephritis 12.9
Moderate hydronephrosis 12.9
Hypersomatotropism 11.3
CRCL 11.3
Segmental glomerulosclerosis 10.6
Distal RTA 10.3
Chronic hyperventilation 10.1
SPD1 9.9
Armanni-Ebstein lesion 9.9
glycinuria 9.9
Acquired disease 9.9
Acute respiratory alkalosis 9.6
FJHN 9.4
Myoglobinuric acute renal failure 9.3
Unilateral renal artery stenosis 9.2
gouty nephropathy 8.8
acetonemia 8.6
proteinuria in pregnancy 8.6
Myeloma cast nephropathy 8.6
Idiopathic hypercalciuria 8.5
Paroxysmal cold hemoglobinuria 8.4
Acute respiratory distress 8.4
Bilateral hydronephrosis 8.3
phosphaturia 8.2
Parathyroid gland 8.2
Parathyroid gland 8.2
Parathyroid gland 8.2
Nodular glomerulosclerosis 8.1
Chronic kidney disease (CKD) 7.9
antidiuresis 7.9
EPV 7.9
nephroptosis 7.9
renal glycosuria 7.9
Proteinuria 7.8
hyperchloremia 7.8
Interstitial fibrosis 7.7
oxalosis 7.7
Hyponatremic 7.6
Chronic pyelonephritis 7.6
microalbuminuria 7.6
EPI 7.6
TINU 7.6
hyporeninemic hypoaldosteronism 7.6
Neonatal hyperbilirubinemia 7.5
Late pregnancy 7.4
Reflux nephropathy 7.4
Chronic anemia 7.4
chronic renal insufficiency 7.3
Nephrogenic systemic fibrosis 7.3
SACS 7.2
kidney hypertrophy 7.2
Pseudohypoaldosteronism 7.2
Hereditary tyrosinemia type I 7.1
nephrosclerosis 7.1
primary hyperoxaluria 7.1
hypercalciuria 7.1
proteinuria 7.1
Imerslund 7.0
Posterior urethral valves 7.0
Hypertensive crisis 7.0
uricosuria 7.0
Coronary artery calcification 7.0
renal insufficiency 6.9
diabetic nephropathy 6.9
aHUS 6.9
renal impairment 6.9
chronic renal failure 6.8
Severe malnutrition 6.8
aminoaciduria 6.8
renal disease 6.7
varicose ulcer 6.7
Congenital nephrotic syndrome 6.7
Goldblatt 6.7
renal ischemia 6.7
Distal renal tubular acidosis 6.7
glomerulosclerosis 6.6
Tumor-induced osteomalacia 6.6
glomerulitis 6.6
hyperphosphatemia 6.6
Laurence-Moon-Biedl syndrome 6.6
chronic glomerulonephritis 6.6
IgM nephropathy 6.6
phosphaturic mesenchymal tumor 6.6
tubular necrosis 6.5
Atherosclerotic renal artery stenosis 6.5
azotemia 6.5
Pulmonary congestion 6.5
Azotemia 6.5
endotheliosis 6.4
nephrocalcinosis 6.4
Secondary hyperparathyroidism 6.4
osteomalacia 6.4
aortic sclerosis 6.3
renal artery stenosis 6.3
acute renal failure 6.3
Growth failure 6.3
Goldblatt hypertension 6.3
anuria 6.2
HYP 6.2
hepatorenal syndrome 6.2
Focal segmental glomerulosclerosis 6.2
SBH 6.2
SBH 6.2
Cardiovascular morbidity 6.2
Autosomal dominant polycystic kidney disease 6.2
hypertensive nephropathy 6.2
Heymann nephritis 6.1
Renovascular hypertension 6.1
IgA nephropathy 6.1
Fanconi syndrome 6.0
renal osteodystrophy 6.0
renal failure 6.0
cystinosis 6.0
uremia 6.0
vitamin D-resistant rickets 6.0
hypochloremia 6.0
glomerulopathy 5.9
rickets 5.9
osteodystrophy 5.9
ganglioneuromatosis 5.9
ureterolithiasis 5.9
nephrosis 5.9
CAN 5.9
hypoaldosteronism 5.8
MPGN 5.8
recurrent urinary tract infection 5.8
ADH 5.8
membranous nephropathy 5.8
nephrotic syndrome 5.8
sponge kidney 5.7
hypercalcemia of malignancy 5.7
RP3 5.7
polycystic kidney 5.6
Central diabetes insipidus 5.6
CSA 5.6
dysproteinemia 5.6
Carotid atherosclerosis 5.6
nephrolithiasis 5.6
hyperparathyroidism 5.6
Gingival overgrowth 5.6
MEST 5.6
renal tubular acidosis 5.5
Bartter's syndrome 5.5
Minimal change disease 5.5
ATN 5.5
trisomy 22 5.5
Vesicoureteral reflux 5.4
MEN 2 5.4
hyperuricemia 5.4
acute tubular necrosis 5.4
hyperoxaluria 5.4
OHD 5.3
CAPA 5.3
testicular teratoma 5.3
Wolf-Hirschhorn syndrome 5.3
glomerulonephritis 5.3
hereditary fructose intolerance 5.3
hypercalcemia 5.2
diffuse sclerosis 5.2
interstitial nephritis 5.2
more...
Symptom
phosphatemia 8.4
unable to sleep 8.4
GI irritation 6.9
Macula 6.0
polyuria 5.7
leg cramps 5.7
oliguria 5.6
hypalgesia 5.4
Lower urinary tract symptoms 5.3
inanition 5.1
disturbed balance 5.1
Catch 4.9
dark urine 4.8
clubbing 4.1
sinus pressure 3.8
enuresis 3.8
ketonuria 3.8
hypoproteinemia 3.7
polydipsia 3.4
chronic back pain 3.3
bone pain 3.3
renal colic 3.2
livedo 3.2
emaciation 2.8
cachexia 2.8
nasal congestion 2.7
pallor 2.6
myalgia 2.5
overweight 2.5
physical appearance 2.3
colic 2.3
hypocapnia 2.2
leg pain 1.9
flank pain 1.8
bradykinesia 1.7
arthralgia 1.7
dysuria 1.6
dry eye 1.5
hypercapnia 1.5
anesthesia 1.5
HSA 1.3
flushing 1.3
dizziness 1.2
exertional dyspnea 1.2
vomiting 1.1
acidity 1.0
apathy 0.9
collapse 0.9
regurgitation 0.9
diarrhea 0.9
weakness 0.9
functional recovery 0.8
acute stress 0.7
wheezing 0.7
nausea and vomiting 0.7
respiratory distress 0.6
paresthesia 0.6
low back pain 0.6
constipation 0.6
shortness of breath 0.5
angina 0.5
Ill 0.4
thinning 0.4
hunger 0.4
lethargy 0.4
back pain 0.3
sleepiness 0.3
tinnitus 0.2
anorexia 0.1
starvation -0.1
hypothermia -0.2
splenomegaly -0.4
fatigue -0.4
abdominal pain -0.4
discomfort -0.6
headache -0.6
nausea -0.6
pain -0.6
cough -0.6
discomfort -0.7
tremor -1.3
seizures -3.4
Drug
Lemildipine 11.9
Carbetimer 9.6
Fabrazyme 9.5
Belatacept 9.4
Doca 9.0
CGS 13080 8.8
Amaryl 8.6
Bendrofluazide 8.5
Iopentol 8.3
Xipamide 8.3
Cardura 8.2
Cardura 8.2
Metolazone 7.9
Lescol 7.8
EPI 7.6
Kayexalate 7.6
Ramipril 7.6
Lescol 7.5
Norvasc 7.5
Arfonad 7.4
Paraplatin 7.3
Epoetin beta 7.3
Piretanide 7.2
Potassium citrate 7.2
Tolvaptan 7.1
GRF 7.1
Pentothal 7.1
Ioversol 7.0
Elvitegravir 7.0
Folic Acid 6.9
Amlodipine besylate 6.9
Amoxapine 6.8
PTH 6.8
Omniscan 6.5
DMSA 6.5
Acetic Acid 6.5
Iohexol 6.5
Tenofovir disoproxil fumarate 6.5
Rasburicase 6.5
Valganciclovir 6.4
Felodipine 6.4
Torasemide 6.2
Lacidipine 6.2
Exenatide 6.2
Basiliximab 6.1
Basiliximab 6.1
Ketorolac tromethamine 6.1
Lacidipine 5.9
Nesiritide 5.9
Chlorothiazide 5.9
Neoral 5.9
NAG 5.8
Cilazapril 5.8
Omniscan 5.8
Everolimus 5.8
Bumetanide 5.8
Bosentan 5.8
Bosentan 5.8
Ibandronate 5.7
Tacrolimus 5.7
Captopril 5.7
Corn oil 5.6
Xeloda 5.6
NLF 5.6
Nephron 5.6
Valsartan 5.6
Perindopril 5.5
2-Methoxyestradiol 5.5
Iodixanol 5.5
Dexrazoxane 5.5
Mycophenolic acid 5.5
Eculizumab 5.4
Inderal 5.4
Misoprostol 5.4
Denosumab 5.4
Daclizumab 5.4
Fenoldopam 5.3
DDAVP 5.3
DDAVP 5.3
Cinacalcet 5.2
Thiopentone 5.2
Diamminedichloroplatinum 5.2
Olmesartan 5.2
Nephron 5.1
Rosuvastatin 5.1
Pirfenidone 5.0
Fenoterol 5.0
Indinavir 5.0
Iopamidol 4.9
Rasburicase 4.9
Isradipine 4.9
Aliskiren 4.9
Pitressin 4.8
TAC 4.8
Epoetin 4.8
Apixaban 4.7
Ketorolac 4.7
Nimesulide 4.7
Angiotensin II 4.7
APD 4.7
Indomethacin 4.7
Amiloride 4.7
Premarin 4.6
Hypaque 4.6
ETA 4.6
Prednisone 4.5
Albumin 4.5
Dial 4.4
Ringer's solution 4.4
Filgrastim 4.4
Ganciclovir 4.3
Amiloride 4.3
PMPA 4.3
Hydrochlorothiazide 4.3
SBT 4.3
Filgrastim 4.2
Pravastatin 4.2
Tenofovir 4.2
Serum albumin 4.2
Liraglutide 4.1
MAP 4.1
Gastro 4.1
Theophylline 3.9
AmBisome 3.9
Cimetidine 3.8
Cimetidine 3.8
Hypaque 3.8
Streptokinase 3.7
Sulpiride 3.7
linolenate 3.7
Taxotere 3.6
Cremophor EL 3.6
VCR 3.6
Lovastatin 3.5
Domperidone 3.5
Colistin 3.5
Rituximab 3.4
Prednisolone 3.4
Glucagon 3.3
Growth hormone 3.3
Coral 3.3
DM1 3.3
Ranitidine 3.3
ROC 3.1
Adenosine triphosphate 3.1
Amoxicillin 3.1
Aprotinin 3.1
Oxaliplatin 3.1
Propofol 2.9
CTX 2.8
Etoposide 2.7
CTX 2.7
Phentolamine 2.7
CEC 2.7
Clonidine 2.7
RFP 2.6
CTX 2.6
Fentanyl 2.6
Fraction 2.6
p75 2.6
more...
Enzyme
glycine N-acyltransferase 7.9
PAH 7.4
PRA 7.0
ketohexokinase 6.2
PHT 5.9
ADH 5.8
fumarylacetoacetate hydrolase 5.7
renin 5.7
STK 5.7
dimethylarginine dimethylaminohydrolase 5.6
NAO 5.4
thromboxane synthase 5.3
ACE 5.2
PRT 5.1
MAP 5.0
alanine aminopeptidase 5.0
H,K-ATPase 4.7
LIS 4.6
VOR 4.6
alpha-galactosidase 4.5
proteinase-3 4.5
fructokinase 4.4
prostacyclin synthase 4.3
AGT 4.3
kallikrein 4.2
succinyl-CoA synthetase 4.2
aminopeptidase A 4.2
SPT 3.8
dipeptidyl peptidase IV 3.8
alcohol dehydrogenase 3.7
MTD 3.7
prostaglandin synthetase 3.6
endothelin-converting enzyme 3.6
NO synthase 3.5
AST 3.5
GCA 3.4
NOS 3.4
calcineurin 3.3
aldose reductase 3.2
12-lipoxygenase 3.1
CD13 3.1
SPT 3.1
carbonic anhydrase 3.0
BIS 3.0
alkaline phosphatase 2.9
gamma-glutamyl transpeptidase 2.9
SCS 2.9
nucleotidase 2.9
guanylate cyclase 2.8
TSA 2.7
tissue kallikrein 2.6
11beta-hydroxysteroid dehydrogenase 2.6
BMT 2.5
MDP 2.5
phosphoglucomutase 2.5
heme oxygenase 2.4
CAD 2.4
transpeptidase 2.4
CAD 2.4
CAD 2.3
sialyltransferase 2.3
sialyltransferase 2.3
sialyltransferase 2.3
5'-nucleotidase 2.3
PTA 2.2
hexosaminidase 2.1
PDE 2.0
cathepsin K 2.0
PAM 2.0
TdT 2.0
glutaminase 2.0
lysozyme 2.0
DCF 2.0
ATPase 1.9
aspartate aminotransferase 1.8
lipoxygenase 1.8
citrate synthase 1.8
phosphoenolpyruvate carboxykinase 1.7
ERK 1.7
adenylate cyclase 1.7
pectinase 1.6
hypoxanthine-guanine phosphoribosyltransferase 1.6
phosphodiesterase 1.5
tryptase 1.5
NADPH oxidase 1.4
phospholipase A2 1.4
alanine aminotransferase 1.4
creatine kinase 1.3
ornithine decarboxylase 1.3
acid phosphatase 1.2
superoxide dismutase 1.2
thromboplastin 1.2
NADPH oxidase 1.2
aldolase 1.1
HSD 1.1
prostate-specific antigen 1.1
lactate dehydrogenase 1.1
tyrosine hydroxylase 1.0
cathepsin B 0.9
xanthine oxidase 0.9
phosphoenolpyruvate carboxykinase 0.9
phosphoenolpyruvate carboxykinase 0.9
MMP 0.8
glutathione peroxidase 0.8
CPT 0.7
MIP 0.6
ceruloplasmin 0.6
tissue plasminogen activator 0.4
phospholipase C 0.3
protein kinase C 0.3
glyceraldehyde-3-phosphate dehydrogenase 0.2
peroxidase 0.2
ribonuclease 0.2
ribonuclease 0.2
P-glycoprotein 0.2
lipoprotein lipase 0.1
glucose-6-phosphate dehydrogenase -0.0
catalase -0.1
RNase -0.1
cdc2 -0.1
thrombin -0.1
focal adhesion kinase -0.2
cytochrome oxidase -0.2
RNase -0.2
plasmin -0.2
MEK -0.3
transcriptase -0.3
glutathione reductase -0.3
CD10 -0.4
mitogen-activated protein kinase -0.5
urokinase-type plasminogen activator -0.5
chymotrypsin -0.5
ACS -0.8
proteasome -0.9
reverse transcriptase -1.1
collagenase -1.3
luciferase -1.3
trypsin -1.5
RNA polymerase -2.2
protein kinase -2.4
Compound
5-Methoxytryptophan 10.3
2-Bromoethylamine hydrobromide 10.3
2-Bromoethylamine hydrobromide 10.3
Sulbenicillin 9.6
Ferrioxamine 8.8
8-iso-PGE2 8.6
Cefonicid 8.6
Methylcitric acid 8.4
TDGA 8.3
Inulin 8.2
Inactin 8.2
BVE 8.2
Tiludronate 8.0
Cefazolin sodium 7.9
Trimethaphan 7.9
Quinapril 7.9
N-acetylalanine 7.8
2-pyrazinecarboxylic acid 7.7
hippurate 7.5
Hippuran 7.5
N'-methylnicotinamide 7.4
PAH 7.4
T 12 7.1
Guanabenz 7.0
creatinine 7.0
N-acetylalanine 6.9
Penbutolol 6.9
DPPD 6.9
3-quinolinecarboxylic acid 6.8
Benazepril 6.8
PD 5 6.7
Fosinopril 6.7
DTPA 6.6
Candesartan 6.6
Enalapril 6.6
Estramustine 6.3
Sodium lactate 6.3
Nitro-L-arginine 6.3
Thiazide 6.2
Steviol 6.2
Netilmicin 6.2
uroporphyrin I 6.2
Fleroxacin 6.2
FUR 6.2
Paricalcitol 6.1
2,4-DP 6.1
SP 1 6.1
Diamminedichloroplatinum 6.0
Tolazoline 6.0
PHT 5.9
Meglumine 5.9
N-methylnicotinamide 5.8
Nitrendipine 5.7
Meclofenamate 5.6
Tempol 5.6
Cyclosporine 5.6
Ajmaline 5.6
DOA 5.6
20-HETE 5.6
Telmisartan 5.5
2-Methoxyestradiol 5.5
Fenoldopam 5.4
CBDCA 5.4
CBDCA 5.4
M 2 5.4
Barbiturate 5.3
aldosterone 5.3
DOCA 5.3
CNA 5.3
Pentoxifylline 5.2
Losartan 5.2
Eplerenone 5.2
CAN 5.1
11,12-EET 5.1
Gb3 5.1
TIF 5.1
TXA2 5.0
Parthenolide 5.0
Uric acid 5.0
Indinavir 5.0
sulfamic acid 4.9
MPE 4.9
INN 4.9
MPT 4.9
EDTA 4.9
EDTA 4.9
sebacic acid 4.8
BNP 4.8
Indomethacin 4.8
SAN 4.8
MAP 4.8
PGH2 4.8
Irbesartan 4.8
DBP 4.8
Miconazole 4.8
Procainamide 4.7
Sodium 4.7
Pravastatin 4.7
Perindopril 4.7
Mycophenolate mofetil 4.7
Enflurane 4.7
Apocynin 4.7
DBD 4.7
Probenecid 4.7
Dextran 4.6
LTA4 4.6
FK506 4.6
Pima 4.6
Salix 4.6
pentosidine 4.6
PGA1 4.6
dipropyl 4.6
DBP 4.6
Premarin 4.6
Phlorizin 4.6
Gentamicin 4.6
Hydrochlorothiazide 4.6
TSC 4.6
DDA 4.6
Fluvastatin 4.6
Hypaque 4.6
DDA 4.6
DDA 4.5
ETA 4.5
Betamethasone 4.5
Cefepime 4.5
Cefazolin 4.5
Angiotensin II 4.5
Ang II 4.5
HPT 4.5
vitamin D 4.5
Domperidone 4.4
Clotrimazole 4.4
urea 4.4
Lovastatin 4.4
HPP 4.4
Dial 4.4
TPCK 4.4
ANCA 4.3
Amiloride 4.3
PMP 4.3
25-dihydroxycholecalciferol 4.3
PMP 4.3
Nembutal 4.3
sodium chloride 4.3
TMP 4.3
sodium 4.3
ASE 4.2
formaldehyde 4.2
Agmatine 4.2
Ornithine 4.2
TMP 4.2
PGE2 4.2
Probucol 4.2
G20 4.2
TMP 4.2
phosphorus 4.2
BAP 4.2
PMP 4.2
Rapamycin 4.2
more...