Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:Q8NEX9 (reductase)
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Human Gene/Protein
DHRS7C 10.2
MOSC2 10.2
CDKN2A interacting protein 10.2
FCR2 10.2
epidermal retinal dehydrogenase 2 10.2
DHRS11 10.2
OR52M1 10.2
Homeobox A13 10.2
TXNL5 10.2
reductase 10.2
26S protease regulatory subunit 8 10.2
pancreas protein 2 10.2
GPSN2 10.2
acetyl-Coenzyme A acetyltransferase 2 10.2
PAN2 protein 10.2
LCytb 10.2
dynein-related protein 10.2
NUCLEOREDOXIN 1 10.2
HsNrbf-1 10.2
ATP synthase mitochondrial F1 complex assembly factor 1 10.2
type 2 cyt-b5 10.2
Heat shock 70kDa protein 1B 10.2
CGI-49 10.2
3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase 10.2
cytochrome b-type NAD(P)H oxidoreductase 10.2
NADH-cytochrome-b5 reductase 9.9
DHRS1 9.7
LTB(4) omega-hydroxylase 9.7
cytochrome b5 reductase-like 9.7
3-hydroxy-3-methylglutaryl CoA 9.6
AKR7A4 9.5
MOSC1 9.5
Glutathione S-transferase theta 1 9.2
Mitochondrial trans-2-enoyl-CoA reductase 9.2
cerebral endothelial cell adhesion molecule 9.2
VKORC1L1 9.2
HDJ2 protein 9.2
DCYTB 9.2
transmembrane 7 superfamily member 2 9.2
DHRSX 9.2
SET and MYND domain-containing protein 1 9.2
MTHF reductase 9.2
hGSTM3-3 9.2
TMEM147 9.2
Carnitine O-palmitoyltransferase 9.2
Rrh 9.2
dihydrofolate reductase-like 1 9.2
DDH1 9.2
flavoprotein-linked monooxygenase 9.2
trans-1,2-dihydrobenzene-1,2-diol dehydrogenase 9.2
Retinol dehydrogenase 11 9.2
carbonyl reductase 4 9.2
Alcohol dehydrogenase 3 9.2
androgen induced protein 9.2
KIAA0099 9.2
CDK5 regulatory subunit-associated protein 1 9.2
hydroxysteroid (17-beta) dehydrogenase 4 9.2
steroid 5 alpha-reductase 9.1
NCB5OR 9.1
PPSH 9.1
DCIP 9.1
SRD5A3 9.0
AKR1D1 9.0
leukotriene B4 12-hydroxydehydrogenase 9.0
RTN4IP1 8.9
aflatoxin B1-aldehyde reductase 8.9
short-chain alcohol dehydrogenase 8.9
Delta(3)-Delta(2)-enoyl-CoA isomerase 8.9
2,4-dienoyl-CoA reductase 8.7
DHCR24 8.7
ectonucleotide pyrophosphatase/phosphodiesterase 5 8.7
FUZ 8.7
peroxisomal 2,4-dienoyl-CoA reductase 8.7
PTP synthase 8.7
JPDI 8.7
Ubiquinol-cytochrome c reductase binding protein 8.7
RIBC1 8.7
HEP27 8.7
transcription factor GATA-5 8.7
Acidic leucine-rich nuclear phosphoprotein 32 family member B 8.7
more...
Disease
Methaemoglobin reductase deficiency 10.2
17-KSR deficiency 10.2
Apparent Mineralocorticoid Excess Syndrome 10.2
Gurrieri syndrome 8.7
ACUG 8.7
R-binder deficiency 8.7
Congenital methemoglobinemia 8.7
Male pseudohermaphroditism 8.4
Factor II mutation 8.2
VKCFD2 8.2
Greenberg dysplasia 8.2
Smith-Lemli-Opitz syndrome 8.0
Hyperprolinemia type I 7.9
hydroxyprolinemia 7.7
hyperlysinemia 7.6
CDG Ix 7.4
Papillophlebitis 7.4
Combined hyperlipidemia 7.4
SPD1 7.2
glycinuria 7.2
toxic amblyopia 7.2
Pityriasis lichenoides chronica 7.2
saccharopinuria 7.1
Reifenstein syndrome 7.0
FENIB 6.9
Frontal fibrosing alopecia 6.9
5-alpha reductase deficiency 6.8
Diffuse alopecia 6.8
17,20-desmolase deficiency 6.8
OPA2 6.8
Dietary selenium deficiency 6.8
FAA4 6.7
Acquired methemoglobinemia 6.6
genitourinary disorder 6.5
Acute myopathy 6.5
transcobalamin II deficiency 6.5
Myoadenylate deaminase deficiency 6.4
L.tropica 6.4
HPC4 6.3
methemoglobinemia 6.3
methionine synthase deficiency 6.2
DTD 6.2
Aortic valve sclerosis 6.1
Transient proteinuria 6.1
Genitourinary Cancers 6.1
PPPP 6.1
PCBD 6.1
Liver fluke infection 6.1
FADS 6.0
HRD 5.9
clotting factor deficiency 5.9
urethrorrhagia 5.9
KAR 5.9
L.donovani 5.8
MYP3 5.8
homocystinemia 5.8
Extrahepatic cholestasis 5.8
DHPR deficiency 5.7
ACP 5.7
KNO2 5.7
SAMS 5.6
Mevalonate kinase deficiency 5.6
tocopherol deficiency 5.6
external genitalia 5.5
Androgen excess 5.5
Primary Sjogren's syndrome 5.5
cblF 5.4
Antithrombin deficiency 5.4
testicular feminization 5.4
AN2 5.4
cystathioninuria 5.4
hypercholesterolemia 5.4
Adrenal suppression 5.3
Reexpansion pulmonary edema 5.3
Complex I deficiency 5.3
prostatic obstruction 5.3
Angular cheilitis 5.3
Oxygen toxicity 5.3
hyperprolinemia 5.3
Enzyme inhibition 5.2
more...
Symptom
Lower urinary tract symptoms 6.5
jaundice of the skin 6.2
iridodonesis 5.7
Acute urinary retention 5.6
Trembling 5.6
difficulty with urination 5.5
prostatism 5.2
masculinization 5.2
Balding 5.2
Reticulocytosis 4.6
nocturnal polyuria 4.6
Stinging 4.5
Urge incontinence 4.2
renal pain 4.2
Urinary symptoms 4.0
abiotrophy 3.9
scaly skin 3.8
male puberty 3.8
peau d'orange 3.7
cyanosis 3.7
disturbed balance 3.4
female puberty 3.3
voice change 3.0
physical exhaustion 2.9
Deafferentation 2.8
frequent urination 2.8
Decreased activity 2.8
myalgia 2.7
Anoxia 2.7
urinary frequency 2.7
generalized pain 2.6
Noise-induced hearing loss 2.6
starvation 2.5
Cushingoid 2.5
Cushingoid 2.4
ACHE 2.4
hyperoxia 2.3
stomach pain 2.3
No adverse effect 1.9
HSA 1.9
dysuria 1.8
hot flashes 1.8
clonus 1.7
belching 1.5
abdominal discomfort 1.5
hepatomegaly 1.4
hypotonia 1.4
Spots 1.4
neurological disability 1.4
tenesmus 1.3
arm pain 1.3
microbial colonization 1.2
POA 1.2
ketonuria 1.1
bloating 1.1
abnormal gait 1.1
muscle stiffness 1.0
weakness 1.0
Wind 0.9
ophthalmoplegia 0.9
right upper quadrant pain 0.8
paraparesis 0.8
CSR 0.8
cerebellar ataxia 0.7
physical appearance 0.7
flushing 0.6
agitation 0.6
livedo 0.5
incoordination 0.4
muscle cramps 0.4
DNA marker 0.4
dysesthesia 0.3
exhaustion 0.3
acidity 0.3
dry skin 0.2
emaciation 0.2
eds 0.2
muscle rigidity 0.2
nasal congestion 0.1
lethargy 0.1
more...
Drug
Lidorestat 10.2
MK-803 9.8
Cerivastatin sodium 9.8
Nanaomycin D 9.7
Cerivastatin sodium 9.6
Trypanothione 9.6
Tropinone 9.2
Dymelor 9.2
MK-733 9.2
Mevastatin 9.1
Finasteride 9.0
Epristeride 8.7
White wax 8.7
Tartronate 8.7
Arteflene 8.7
(-)-Carnitine 8.7
Sodium dehydroacetate 8.7
Lycium fruit 8.7
CS-514 8.6
Dutasteride 8.5
Isoconazole 8.2
Monatepil maleate 8.2
Pravastatin 8.1
Pentaerythritol tetranitrate 8.0
Crilvastatin 7.9
Schisandra fruit 7.9
Sulfopyruvate 7.9
Lescol 7.9
Lescol 7.7
Lovastatin 7.7
Ammonium phosphate 7.7
Minalrestat 7.7
Cupric chloride 7.7
Simvastatin 7.6
Lifibrol 7.5
RXM 7.4
Rosuvastatin calcium 7.3
FAD 7.3
Indigocarmine 7.2
Zenarestat 7.2
2,4,6-Trinitrophenol 7.2
Lipitor 7.2
Lipitor 7.1
Lipitor 7.1
NADH 7.1
Dihydrotestosterone 7.1
Colesevelam 7.1
Timiperone 7.1
Ranirestat 7.1
Moco 6.9
Armes 6.9
Rosuvastatin 6.9
Ponalrestat 6.8
Mepartricin 6.8
Factrel 6.8
DHT 6.7
Neotrofin 6.7
Capravirine 6.7
DHT 6.6
Tirapazamine 6.6
Tricyclazole 6.5
Oleic Acid 6.5
4-Hydroxycoumarin 6.5
Tirilazad mesylate 6.5
Fidarestat 6.4
Fidarestat 6.4
Formycin 6.4
Inspra 6.4
Tirilazad mesylate 6.3
Pitavastatin calcium 6.3
E.A.C 6.3
Alrestatin 6.2
Flavin 6.2
Epalrestat 6.2
Carbenoxolone 6.1
Equilenin 6.1
Chlorate 6.1
THF 5.9
Ganaxolone 5.9
Anthramycin 5.9
more...
Enzyme
2-dehydro-3-deoxy-D-pentonate aldolase 10.2
1,2-dihydrovomilenine reductase 10.2
juglone hydroxylase 10.2
EC 1.1.1.161 10.2
bis-gamma-glutamylcystine reductase 10.2
hydroxybenzoquinone reductase 10.2
trihydroxypterocarpan dimethylallyltransferase 10.2
phthalyl amidase 10.2
EC 3.1.2.5 10.2
4-sulfobenzoate dioxygenase 10.2
L-threonic acid dehydrogenase 10.2
ethanolamine oxidase 10.2
EC 1.8.4.9 10.2
3-methylbutanal reductase 10.2
progesterone reductase 10.2
EC 1.3.1.23 10.2
EC 1.1.1.251 10.2
mevaldate reductase 10.2
EC 3.5.4.26 10.2
EC 1.1.1.193 10.2
EC 1.1.1.168 10.2
2-aminobenzenesulfonate 2,3-dioxygenase 10.2
berbamunine synthase 10.2
formyltransferase, dihydrofolate 10.2
2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase 10.2
mevaldate reductase 10.2
acyl-protein synthetase 10.2
sterol-4alpha-carboxylate 3-dehydrogenase 10.2
reductase phosphatase 9.9
2-oxo-1,2-dihydroquinoline 8-monooxygenase 9.8
prostaglandin 13-reductase 9.8
xylitol dehydrogenase 9.7
xylitol dehydrogenase 9.7
cob(II)alamin reductase 9.7
3-KSR 9.7
isoflavone 3'-hydroxylase 9.7
dinitrogenase reductase-activating glycohydrolase 9.7
methylene-H4MPT reductase 9.7
sarcosine reductase 9.7
EC 1.1.1.219 9.7
UlaE 9.7
3,9-dihydroxypterocarpan 6a-hydroxylase 9.7
ketimine reductase 9.6
EC 1.1.1.101 9.5
2-aminobenzoyl-CoA monooxygenase/reductase 9.4
beta-ketoacyl reductase 9.3
anthocyanidin synthase 9.3
riboflavin hydrolase 9.2
isopiperitenol dehydrogenase 9.2
alpha-keto-beta-deoxy-D-glucarate aldolase 9.2
quinaldic acid 4-oxidoreductase 9.2
NADP+-dependent 15-hydroxyprostaglandin dehydrogenase 9.2
3-methyleneoxindole reductase 9.2
3alpha(17beta)-HSD 9.2
CO-methylating acetyl-CoA synthase 9.2
MMA(V) reductase 9.2
EC 1.3.99.6 9.2
quinaldic acid 4-oxidoreductase 9.2
allyl-alcohol dehydrogenase 9.2
L-idonate 5-dehydrogenase 9.2
cortisone alpha-reductase 9.2
EC 1.1.4.1 9.2
ureidoglycolate dehydrogenase 9.2
EC 1.8.4.1 9.2
mycothione reductase 9.2
PAPS reductase 9.1
aquacobalamin reductase 9.1
aquacobalamin reductase 9.1
ecdysone oxidase 9.0
flavanone 3-hydroxylase 9.0
trans-2-enoyl-CoA reductase 8.9
dinucleotide phosphate reductase 8.9
flavanone 4-reductase 8.9
prostaglandin D2 dehydrogenase 8.9
2-aminobenzoate-CoA ligase 8.9
anthocyanin 5-aromatic acyltransferase 8.9
UlaD 8.9
cycloeucalenol-obtusifoliol isomerase 8.9
L-arabitol dehydrogenase 8.9
O-acetyl-L-serine acetate-lyase 8.9
more...
Compound
Ansatrienin A 10.2
C27H46O 10.2
o-Chloroacetophenone 10.2
DHAPR 10.2
p-Nitrobenzyl chloride 10.2
19-Noretiocholanolone 10.2
5-Carboxy-2-pentenoyl-CoA 10.2
C15H24O 10.2
C22H24N2O 10.2
C27H46O 10.2
C27H46O 10.2
pregnane-3,17,20-triol 10.2
Blue RX 10.2
C27H46O 10.2
5-Bromoisatin 10.2
C27H46O 10.2
16alpha,17alpha-Epoxyprogesterone 10.2
2-C-Methyl-D-erythritol 2,4-cyclodiphosphate 10.2
C22H24N2O 10.2
C22H24N2O 10.2
C22H24N2O 10.2
C15H24O 10.2
UDP-N-acetylglucosamine enolpyruvate 10.2
C22H24N2O 10.2
Vomilenine 10.2
C27H46O 10.2
C15H24O 10.2
C27H46O 10.2
2-Methylacetoacetyl-CoA 10.2
C22H24N2O 10.2
C27H46O 10.2
C27H46O 10.2
C15H24O 10.2
C15H24O 10.2
C15H24O 10.2
C15H24O 10.2
2-phenylpropanal oxime 10.2
6-lactoyl-5,6,7,8-tetrahydropterin 10.2
C27H46O 10.2
C15H24O 10.2
C15H24O 10.2
C15H24O 10.2
Vitamin K epoxide 9.9
Vestitone 9.8
D-Erythrulose 9.8
5,10-Methylenetetrahydrofolate 9.7
HMG-CoA 9.7
glutaryl-CoA 9.6
Maleylacetate 9.5
p-Nitrobenzaldehyde 9.5
GDP-4-keto-6-deoxy-D-mannose 9.3
C27H46O 9.2
Bostrycoidin 9.2
C16H24O2 9.2
(Diacetoxyiodo)benzene 9.2
Morfamquat 9.2
Pyruvic oxime 9.2
(2-Chlorobenzylidene)malononitrile 9.2
Salutaridine 9.2
Tetradecanoyl-CoA 9.2
C14H22O 9.2
C16H22O8 9.2
5alpha-cholest-8-en-3beta-ol 9.2
C21H30O2 9.2
Glycerol-2-phosphate 9.2
DCIP 9.1
Diphenyliodonium chloride 9.0
Morphinone 9.0
Crotonyl-CoA 9.0
Tropinone 9.0
cholest-7-en-3-one 8.9
Jadomycin B 8.9
ethyl 4-chloro-3-oxobutanoate 8.9
5,10-methylene-THF 8.9
Acetohexamide 8.9
ML-236B 8.8
Biliverdin 8.7
bromomethanesulfonic acid 8.7
C2B4 8.7
Pyridomycin 8.7
more...