Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:Q8NEX9 (
reductase
)
26,410
document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
reductase
26410
NADPH
3879
NADH
2579
Sep
1789
Mol
1637
microsomal
1497
HMG-CoA reductase
1494
cytochrome
1266
P450
1056
cytochrome P450
950
NAD
918
ferredoxin
891
NADP
850
cytochrome c
786
oxidoreductase
739
FAD
698
cytochrome P-450
664
Pseudomonas
617
ATP
590
catalase
580
superoxide dismutase
539
GSH
514
endoplasmic reticulum
511
thioredoxin
458
FMN
431
flavoprotein
429
polypeptide
407
membrane-bound
396
NADPH-cytochrome P-450 reductase
387
androgen receptor
381
peroxidase
372
insulin
371
NADP+
365
cytochrome b5
359
glutathione peroxidase
321
glutathione reductase
305
aromatase
301
HDL
295
SDS
288
NMR
283
cytochrome b
271
EPR
258
LDL receptor
252
ubiquinone
238
nitric oxide synthase
235
HSD
225
fused
223
ADP
222
ATPase
218
NAD+
206
CPR
200
DT-diaphorase
199
hemoglobin
193
calmodulin
186
xenobiotic
184
alcohol dehydrogenase
176
ribonucleotide reductase
174
Gen
172
thioredoxin reductase
172
methemoglobin
171
aldo-keto reductase
169
SOD
168
fatty acid synthase
166
lactate dehydrogenase
164
glutathione S-transferase
163
dimeric
158
AMP
144
dihydrofolate reductase
144
GSNOR
140
HSD1
139
CO2
135
alkaline phosphatase
129
glucose-6-phosphate dehydrogenase
129
Prx
129
delta 4
128
Smith-Lemli-Opitz syndrome
126
cytokine
124
ACP
124
CYP3A4
119
cytochrome c oxidase
118
more...
Disease
cancer
1023
tumor
578
hypercholesterolemia
519
GSH
514
atherosclerosis
488
prostate cancer
379
diabetes
361
Mycobacterium
341
tuberculosis
305
SDS
288
cardiovascular disease
278
hyperlipidemia
233
hypertension
204
hepatocellular carcinoma
196
carcinogenesis
190
coronary heart disease
189
coronary artery disease
184
obesity
166
breast cancer
165
Steroids
162
stroke
155
Alzheimer's disease
155
carcinoma
149
dyslipidemia
138
myopathy
135
cold
131
Smith-Lemli-Opitz syndrome
129
ACP
124
plaque
120
ischemia
114
myocardial infarction
103
pheochromocytoma
102
hyperhomocysteinemia
102
PCC
99
leukemia
88
depression
87
tumor growth
86
type 2 diabetes
86
epididymis
84
external genitalia
83
malaria
77
methemoglobinemia
73
mole
72
mole
72
metabolic syndrome
71
Klebsiella
70
dehydration
69
SEM
67
neuroblastoma
65
MCF
64
seminal vesicles
64
adenocarcinoma
62
fatty liver
61
iron deficiency
58
renal disease
57
hyperglycemia
57
tumorigenesis
57
vascular disease
55
FAS
52
colorectal cancer
52
osteoporosis
51
lung cancer
51
heart failure
50
acne
50
Parkinson's disease
49
mental retardation
48
mental retardation
48
AGA
46
NAME
46
melanoma
45
gallstones
44
uterus
43
erectile dysfunction
43
multiple sclerosis
43
colon cancer
43
epilepsy
43
asthma
42
polycystic ovary syndrome
41
Chagas
41
PDB
40
more...
Symptom
starvation
117
masculinization
79
weakness
62
pain
54
seizures
51
cyanosis
41
myalgia
36
headache
27
fatigue
25
anesthesia
25
hyperoxia
21
diarrhea
19
agitation
15
collapse
15
acidity
15
Lower urinary tract symptoms
14
exhaustion
14
hepatomegaly
13
hypotonia
13
tremor
12
overweight
10
nausea
10
ataxia
10
thinning
9
HSA
9
prostatism
9
flushing
8
abdominal pain
8
respiratory distress
7
dysuria
7
angina
7
anorexia
7
hypothermia
6
analgesia
6
constipation
6
insomnia
6
urinary frequency
6
vomiting
5
Acute urinary retention
5
cerebellar ataxia
5
dyspnea
5
lethargy
5
ophthalmoplegia
5
spasticity
5
Wind
4
paraparesis
4
chest pain
4
shortness of breath
4
dystonia
4
splenomegaly
4
Ill
4
dizziness
4
abdominal discomfort
4
hemiplegia
3
discomfort
3
chills
3
hot flashes
3
nocturnal polyuria
3
acute stress
3
syncope
3
dysarthria
3
bloating
3
Anoxia
3
pelvic pain
3
discomfort
3
functional recovery
3
Decreased activity
3
erythema
3
hemoptysis
2
incoordination
2
cachexia
2
disturbed balance
2
ENT
2
abnormal gait
2
muscle stiffness
2
neurological disability
2
pallor
2
scaly skin
2
arthralgia
2
cough
2
more...
Drug
NADH
2548
FAD
698
THF
412
ascorbate
327
Simvastatin
260
lysine
242
Lovastatin
222
DHT
191
DHT
191
Pravastatin
184
Finasteride
182
vitamin E
120
Cardiovasc
116
Dermatol
110
MAP
99
ROS
97
Glutathione
79
Trypanothione
78
Gel
65
Kenyan
63
niacin
55
Leaf
54
Asn
53
Dihydrotestosterone
48
Heme
48
CDP
45
Rosuvastatin
45
CPR
43
Triclosan
43
Nitric Oxide
36
Dutasteride
35
Vitamin K
32
Ethanol
32
BH4
29
EE2
27
IFN-gamma
26
nitroglycerin
24
citric acid
24
pyridoxal phosphate
23
lactose
22
Isoniazid
21
Flavin
21
Mevastatin
19
Adriamycin
18
caffeine
18
Vitamin E
18
Estrogens
17
Ketoconazole
17
IL-2
16
CS-514
16
Gemfibrozil
16
NBT
16
ABC
15
ALA
15
Bifidobacterium
14
Cibacron Blue
14
Riboflavin
14
MK-733
14
NH3
14
Digitalis
14
Glycerol
13
Lipitor
13
-deoxyadenosine
13
Lipitor
13
Indomethacin
13
Angiotensin II
12
ICI
12
Nephron
12
Arsenic trioxide
12
Ezetimibe
12
DNase I
12
Monit
12
HCG
11
R1881
11
EPA
11
Pregnenolone
11
Carbenoxolone
11
all-trans-retinol
10
Mutagen
10
Capsicum
10
more...
Enzyme
CPR
699
catalase
619
superoxide dismutase
596
diaphorase
511
peroxidase
406
NQO1
367
glutathione peroxidase
339
glutathione reductase
318
nitrate reductase
299
alcohol dehydrogenase
294
nitrate reductase
293
nitrate reductase
293
nitrate reductase
291
nitrate reductase
289
nitrate reductase
289
complex I
281
ATPase
279
nitrite reductase
269
nitrite reductase
266
demethylase
265
nitrite reductase
257
succinate dehydrogenase
250
HSD
242
nitrogenase
235
glutathione S-transferase
234
aldose reductase
206
3-hydroxy-3-methylglutaryl-CoA reductase
201
ribonucleotide reductase
197
xylitol dehydrogenase
193
peroxiredoxin
189
xylitol dehydrogenase
189
11beta-hydroxysteroid dehydrogenase
186
NADPH-diaphorase
182
thioredoxin reductase
177
ribonucleotide reductase
177
lactate dehydrogenase
176
glucose-6-phosphate dehydrogenase
168
NADH-cytochrome b5 reductase
166
dihydrofolate reductase
161
adrenodoxin reductase
157
diaphorase
157
NO synthase
153
3-hydroxy-3-methylglutaryl coenzyme A reductase
148
chalcone synthase
143
mitogen-activated protein kinase
142
trypsin
138
cytochrome oxidase
135
alkaline phosphatase
130
NADPH oxidase
129
CYP3A4
119
cholesterol acyltransferase
119
NADPH oxidase
118
luciferase
117
hydrogenase
117
NADH dehydrogenase
116
hydrogenase
116
succinic dehydrogenase
114
aldehyde reductase
111
aldehyde reductase
109
protein kinase
108
ACS
107
aldehyde reductase
104
creatine kinase
104
aldehyde dehydrogenase
99
carbonyl reductase
97
acid phosphatase
94
xanthine oxidase
87
farnesyltransferase
83
formate dehydrogenase
82
aryl hydrocarbon hydroxylase
81
ERK
81
alanine aminotransferase
81
nitrous oxide reductase
79
AMP-activated protein kinase
78
heme oxygenase
77
methionine synthase
77
formate dehydrogenase
76
formate dehydrogenase
76
aspartate aminotransferase
76
flavin reductase
75
more...
Compound
NADPH
3885
NADPH
3882
NADH
2548
oxygen
2015
Dec
1946
DNA
1694
CoA
1519
iron
1450
NADP
1242
NAD
1102
nitric oxide
1004
HMG-CoA
979
phosphate
970
hydrogen
922
NAD
918
glucose
917
water
858
Clin
780
sodium
770
nitrogen
746
sulfate
725
acetate
723
FAD
700
cysteine
663
nitrate
650
ATP
591
GSH
565
GSH
565
nicotinamide
526
arginine
454
ethanol
449
FMN
448
xylose
448
methionine
430
His
411
copper
393
ammonium
349
lysine
349
CO2
342
aldehyde
338
methane
326
calcium
325
hydroxide
315
SDS
312
tyrosine
311
salt
310
aldehyde
298
H2O2
285
Cholesterol
263
galactose
260
alanine
258
glycerol
255
molybdenum
253
ubiquinone
253
pyridine
251
DHT
237
ADP
236
homocysteine
231
ADP
225
DMSO
223
ADP
222
glutamate
220
zinc
214
glutaryl-CoA
212
serine
198
pentose
184
alcohol dehydrogenase
182
Phe
181
NH2
181
ammonia
177
Cardiol
176
DEAE
175
androstane
174
GSSG
171
aniline
166
potassium
165
cyanide
154
AMP
154
Lovastatin
154
Atorvastatin
152
more...