Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:Q8NEX9 (reductase)
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Human Gene/Protein
CDKN2A interacting protein 10.2
HsNrbf-1 10.2
NUCLEOREDOXIN 1 10.2
CGI-49 10.2
LCytb 10.2
3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase 10.2
MOSC2 10.2
DHRS7C 10.2
cytochrome b-type NAD(P)H oxidoreductase 10.2
acetyl-Coenzyme A acetyltransferase 2 10.2
ATP synthase mitochondrial F1 complex assembly factor 1 10.2
type 2 cyt-b5 10.2
reductase 10.2
TXNL5 10.2
GPSN2 10.2
Heat shock 70kDa protein 1B 10.2
PAN2 protein 10.2
Homeobox A13 10.2
OR52M1 10.2
dynein-related protein 10.2
DHRS11 10.2
26S protease regulatory subunit 8 10.2
epidermal retinal dehydrogenase 2 10.2
FCR2 10.2
pancreas protein 2 10.2
NADH-cytochrome-b5 reductase 9.9
LTB(4) omega-hydroxylase 9.7
DHRS1 9.7
cytochrome b5 reductase-like 9.7
3-hydroxy-3-methylglutaryl CoA 9.6
AKR7A4 9.5
MOSC1 9.5
DCYTB 9.2
carbonyl reductase 4 9.2
hGSTM3-3 9.2
Retinol dehydrogenase 11 9.2
flavoprotein-linked monooxygenase 9.2
CDK5 regulatory subunit-associated protein 1 9.2
VKORC1L1 9.2
Glutathione S-transferase theta 1 9.2
more...
Disease
17-KSR deficiency 10.2
Apparent Mineralocorticoid Excess Syndrome 10.2
Methaemoglobin reductase deficiency 10.2
ACUG 8.7
Congenital methemoglobinemia 8.7
R-binder deficiency 8.7
Gurrieri syndrome 8.7
Male pseudohermaphroditism 8.4
Greenberg dysplasia 8.2
VKCFD2 8.2
Factor II mutation 8.2
Smith-Lemli-Opitz syndrome 8.0
Hyperprolinemia type I 7.9
hydroxyprolinemia 7.7
hyperlysinemia 7.6
CDG Ix 7.4
Papillophlebitis 7.4
Combined hyperlipidemia 7.4
SPD1 7.2
Pityriasis lichenoides chronica 7.2
glycinuria 7.2
toxic amblyopia 7.2
saccharopinuria 7.1
Reifenstein syndrome 7.0
FENIB 6.9
Frontal fibrosing alopecia 6.9
5-alpha reductase deficiency 6.8
17,20-desmolase deficiency 6.8
Diffuse alopecia 6.8
OPA2 6.8
Dietary selenium deficiency 6.8
FAA4 6.7
Acquired methemoglobinemia 6.6
Acute myopathy 6.5
genitourinary disorder 6.5
transcobalamin II deficiency 6.5
L.tropica 6.4
Myoadenylate deaminase deficiency 6.4
HPC4 6.3
methemoglobinemia 6.3
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Symptom
Lower urinary tract symptoms 6.5
jaundice of the skin 6.2
iridodonesis 5.7
Acute urinary retention 5.6
Trembling 5.6
difficulty with urination 5.5
prostatism 5.2
masculinization 5.2
Balding 5.2
Reticulocytosis 4.6
nocturnal polyuria 4.6
Stinging 4.5
Urge incontinence 4.2
renal pain 4.2
Urinary symptoms 4.0
abiotrophy 3.9
scaly skin 3.8
male puberty 3.8
peau d'orange 3.7
cyanosis 3.7
disturbed balance 3.4
female puberty 3.3
voice change 3.0
physical exhaustion 2.9
Deafferentation 2.8
frequent urination 2.8
Decreased activity 2.8
myalgia 2.7
Anoxia 2.7
urinary frequency 2.7
generalized pain 2.6
Noise-induced hearing loss 2.6
starvation 2.5
Cushingoid 2.5
Cushingoid 2.4
ACHE 2.4
hyperoxia 2.3
stomach pain 2.3
No adverse effect 1.9
HSA 1.9
more...
Drug
Lidorestat 10.2
MK-803 9.8
Cerivastatin sodium 9.8
Nanaomycin D 9.7
Cerivastatin sodium 9.6
Trypanothione 9.6
Dymelor 9.2
Tropinone 9.2
MK-733 9.2
Mevastatin 9.1
Finasteride 9.0
Arteflene 8.7
Tartronate 8.7
Epristeride 8.7
(-)-Carnitine 8.7
Sodium dehydroacetate 8.7
White wax 8.7
Lycium fruit 8.7
CS-514 8.6
Dutasteride 8.5
Isoconazole 8.2
Monatepil maleate 8.2
Pravastatin 8.1
Pentaerythritol tetranitrate 8.0
Crilvastatin 7.9
Schisandra fruit 7.9
Sulfopyruvate 7.9
Lescol 7.9
Lescol 7.7
Lovastatin 7.7
Ammonium phosphate 7.7
Minalrestat 7.7
Cupric chloride 7.7
Simvastatin 7.6
Lifibrol 7.5
RXM 7.4
Rosuvastatin calcium 7.3
FAD 7.3
2,4,6-Trinitrophenol 7.2
Indigocarmine 7.2
more...
Enzyme
hydroxybenzoquinone reductase 10.2
juglone hydroxylase 10.2
EC 3.5.4.26 10.2
4-sulfobenzoate dioxygenase 10.2
3-methylbutanal reductase 10.2
EC 1.8.4.9 10.2
phthalyl amidase 10.2
acyl-protein synthetase 10.2
ethanolamine oxidase 10.2
L-threonic acid dehydrogenase 10.2
2-dehydro-3-deoxy-D-pentonate aldolase 10.2
2-aminobenzenesulfonate 2,3-dioxygenase 10.2
formyltransferase, dihydrofolate 10.2
bis-gamma-glutamylcystine reductase 10.2
EC 1.1.1.168 10.2
EC 1.1.1.251 10.2
berbamunine synthase 10.2
progesterone reductase 10.2
sterol-4alpha-carboxylate 3-dehydrogenase 10.2
mevaldate reductase 10.2
trihydroxypterocarpan dimethylallyltransferase 10.2
EC 3.1.2.5 10.2
EC 1.1.1.161 10.2
mevaldate reductase 10.2
EC 1.3.1.23 10.2
2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase 10.2
1,2-dihydrovomilenine reductase 10.2
EC 1.1.1.193 10.2
reductase phosphatase 9.9
prostaglandin 13-reductase 9.8
2-oxo-1,2-dihydroquinoline 8-monooxygenase 9.8
xylitol dehydrogenase 9.7
xylitol dehydrogenase 9.7
3-KSR 9.7
3,9-dihydroxypterocarpan 6a-hydroxylase 9.7
EC 1.1.1.219 9.7
methylene-H4MPT reductase 9.7
sarcosine reductase 9.7
UlaE 9.7
dinitrogenase reductase-activating glycohydrolase 9.7
more...
Compound
DHAPR 10.2
C27H46O 10.2
C15H24O 10.2
Ansatrienin A 10.2
C15H24O 10.2
19-Noretiocholanolone 10.2
5-Bromoisatin 10.2
C22H24N2O 10.2
C27H46O 10.2
C22H24N2O 10.2
C15H24O 10.2
16alpha,17alpha-Epoxyprogesterone 10.2
C27H46O 10.2
C27H46O 10.2
Vomilenine 10.2
C15H24O 10.2
pregnane-3,17,20-triol 10.2
C22H24N2O 10.2
C22H24N2O 10.2
C27H46O 10.2
2-phenylpropanal oxime 10.2
C27H46O 10.2
C22H24N2O 10.2
C15H24O 10.2
p-Nitrobenzyl chloride 10.2
C15H24O 10.2
2-Methylacetoacetyl-CoA 10.2
C27H46O 10.2
C22H24N2O 10.2
6-lactoyl-5,6,7,8-tetrahydropterin 10.2
C15H24O 10.2
5-Carboxy-2-pentenoyl-CoA 10.2
C15H24O 10.2
C15H24O 10.2
C27H46O 10.2
2-C-Methyl-D-erythritol 2,4-cyclodiphosphate 10.2
Blue RX 10.2
C15H24O 10.2
C27H46O 10.2
o-Chloroacetophenone 10.2
more...