Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:Q8NEX9 (
reductase
)
26,410
document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
reductase
26410
NADPH
3879
NADH
2579
Sep
1789
Mol
1637
microsomal
1497
HMG-CoA reductase
1494
cytochrome
1266
P450
1056
cytochrome P450
950
NAD
918
ferredoxin
891
NADP
850
cytochrome c
786
oxidoreductase
739
FAD
698
cytochrome P-450
664
Pseudomonas
617
ATP
590
catalase
580
superoxide dismutase
539
GSH
514
endoplasmic reticulum
511
thioredoxin
458
FMN
431
flavoprotein
429
polypeptide
407
membrane-bound
396
NADPH-cytochrome P-450 reductase
387
androgen receptor
381
peroxidase
372
insulin
371
NADP+
365
cytochrome b5
359
glutathione peroxidase
321
glutathione reductase
305
aromatase
301
HDL
295
SDS
288
NMR
283
more...
Disease
cancer
1023
tumor
578
hypercholesterolemia
519
GSH
514
atherosclerosis
488
prostate cancer
379
diabetes
361
Mycobacterium
341
tuberculosis
305
SDS
288
cardiovascular disease
278
hyperlipidemia
233
hypertension
204
hepatocellular carcinoma
196
carcinogenesis
190
coronary heart disease
189
coronary artery disease
184
obesity
166
breast cancer
165
Steroids
162
Alzheimer's disease
155
stroke
155
carcinoma
149
dyslipidemia
138
myopathy
135
cold
131
Smith-Lemli-Opitz syndrome
129
ACP
124
plaque
120
ischemia
114
myocardial infarction
103
pheochromocytoma
102
hyperhomocysteinemia
102
PCC
99
leukemia
88
depression
87
type 2 diabetes
86
tumor growth
86
epididymis
84
external genitalia
83
more...
Symptom
starvation
117
masculinization
79
weakness
62
pain
54
seizures
51
cyanosis
41
myalgia
36
headache
27
anesthesia
25
fatigue
25
hyperoxia
21
diarrhea
19
collapse
15
acidity
15
agitation
15
Lower urinary tract symptoms
14
exhaustion
14
hepatomegaly
13
hypotonia
13
tremor
12
ataxia
10
overweight
10
nausea
10
thinning
9
prostatism
9
HSA
9
abdominal pain
8
flushing
8
dysuria
7
respiratory distress
7
anorexia
7
angina
7
constipation
6
insomnia
6
analgesia
6
urinary frequency
6
hypothermia
6
vomiting
5
Acute urinary retention
5
dyspnea
5
more...
Drug
NADH
2548
FAD
698
THF
412
ascorbate
327
Simvastatin
260
lysine
242
Lovastatin
222
DHT
191
DHT
191
Pravastatin
184
Finasteride
182
vitamin E
120
Cardiovasc
116
Dermatol
110
MAP
99
ROS
97
Glutathione
79
Trypanothione
78
Gel
65
Kenyan
63
niacin
55
Leaf
54
Asn
53
Heme
48
Dihydrotestosterone
48
CDP
45
Rosuvastatin
45
Triclosan
43
CPR
43
Nitric Oxide
36
Dutasteride
35
Ethanol
32
Vitamin K
32
BH4
29
EE2
27
IFN-gamma
26
citric acid
24
nitroglycerin
24
pyridoxal phosphate
23
lactose
22
more...
Enzyme
CPR
699
catalase
619
superoxide dismutase
596
diaphorase
511
peroxidase
406
NQO1
367
glutathione peroxidase
339
glutathione reductase
318
nitrate reductase
299
alcohol dehydrogenase
294
nitrate reductase
293
nitrate reductase
293
nitrate reductase
291
nitrate reductase
289
nitrate reductase
289
complex I
281
ATPase
279
nitrite reductase
269
nitrite reductase
266
demethylase
265
nitrite reductase
257
succinate dehydrogenase
250
HSD
242
nitrogenase
235
glutathione S-transferase
234
aldose reductase
206
3-hydroxy-3-methylglutaryl-CoA reductase
201
ribonucleotide reductase
197
xylitol dehydrogenase
193
xylitol dehydrogenase
189
peroxiredoxin
189
11beta-hydroxysteroid dehydrogenase
186
NADPH-diaphorase
182
thioredoxin reductase
177
ribonucleotide reductase
177
lactate dehydrogenase
176
glucose-6-phosphate dehydrogenase
168
NADH-cytochrome b5 reductase
166
dihydrofolate reductase
161
diaphorase
157
more...
Compound
NADPH
3885
NADPH
3882
NADH
2548
oxygen
2015
Dec
1946
DNA
1694
CoA
1519
iron
1450
NADP
1242
NAD
1102
nitric oxide
1004
HMG-CoA
979
phosphate
970
hydrogen
922
NAD
918
glucose
917
water
858
Clin
780
sodium
770
nitrogen
746
sulfate
725
acetate
723
FAD
700
cysteine
663
nitrate
650
ATP
591
GSH
565
GSH
565
nicotinamide
526
arginine
454
ethanol
449
xylose
448
FMN
448
methionine
430
His
411
copper
393
lysine
349
ammonium
349
CO2
342
aldehyde
338
more...