Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:Q8NEX9 (reductase)
 26,410 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
reductase 26410
NADPH 3879
NADH 2579
Sep 1789
Mol 1637
microsomal 1497
HMG-CoA reductase 1494
cytochrome 1266
P450 1056
cytochrome P450 950
NAD 918
ferredoxin 891
NADP 850
cytochrome c 786
oxidoreductase 739
FAD 698
cytochrome P-450 664
Pseudomonas 617
ATP 590
catalase 580
superoxide dismutase 539
GSH 514
endoplasmic reticulum 511
thioredoxin 458
FMN 431
flavoprotein 429
polypeptide 407
membrane-bound 396
NADPH-cytochrome P-450 reductase 387
androgen receptor 381
peroxidase 372
insulin 371
NADP+ 365
cytochrome b5 359
glutathione peroxidase 321
glutathione reductase 305
aromatase 301
HDL 295
SDS 288
NMR 283
cytochrome b 271
EPR 258
LDL receptor 252
ubiquinone 238
nitric oxide synthase 235
HSD 225
fused 223
ADP 222
ATPase 218
NAD+ 206
CPR 200
DT-diaphorase 199
hemoglobin 193
calmodulin 186
xenobiotic 184
alcohol dehydrogenase 176
ribonucleotide reductase 174
thioredoxin reductase 172
Gen 172
methemoglobin 171
aldo-keto reductase 169
SOD 168
fatty acid synthase 166
lactate dehydrogenase 164
glutathione S-transferase 163
dimeric 158
AMP 144
dihydrofolate reductase 144
GSNOR 140
HSD1 139
CO2 135
glucose-6-phosphate dehydrogenase 129
Prx 129
alkaline phosphatase 129
delta 4 128
Smith-Lemli-Opitz syndrome 126
ACP 124
cytokine 124
CYP3A4 119
aldose reductase 118
cytochrome c oxidase 118
diaphorase 117
prothrombin 117
CYP 113
3 beta-hydroxysteroid dehydrogenase 113
phosphatase 112
Rho 110
NADH dehydrogenase 109
3 beta-HSD 107
glutaredoxin 107
methyltransferase 106
Cytochrome P450 104
aldehyde reductase 102
heme oxygenase-1 100
antioxidant enzyme 98
PCC 98
ROS 97
B12 97
gut 97
ACS 95
acid phosphatase 94
CYP1A2 93
collagen 91
short-chain dehydrogenase/reductase 91
carbonyl reductase 91
membrane protein 89
glucose dehydrogenase 89
inducible nitric oxide synthase 86
estrogen receptor 86
tRNA 85
p53 85
xanthine oxidase 83
steroid 5 alpha-reductase 82
CYP1A1 81
FSH 81
unknown function 81
lipopolysaccharide 81
Met 81
protein S 79
CYP7A1 79
HSD2 79
apoE 77
17 beta-hydroxysteroid dehydrogenase 77
methionine synthase 76
glycoprotein 76
neuronal nitric oxide synthase 75
albumin 75
creatine kinase 74
apolipoprotein B 74
epididymal 73
flavin reductase 73
Aromatase 73
biliverdin reductase 73
caspase-3 72
CYP2E1 72
Thioredoxin 72
apolipoprotein 71
H. influenzae 71
CYP3A 71
Bot 70
quinone reductase 70
transcriptional regulator 69
adrenodoxin reductase 69
RSH 69
GTP 67
NQO1 67
Trx 67
RhoA 66
acetyl-CoA carboxylase 66
C-reactive protein 65
transferrin 65
factor V Leiden 65
lipoprotein lipase 65
SRD5A2 65
endothelial nitric oxide synthase 64
ubiquitin 64
threonine 64
HMG-CoA synthase 64
P450scc 64
squalene synthase 63
more...
Disease
cancer 1023
tumor 578
hypercholesterolemia 519
GSH 514
atherosclerosis 488
prostate cancer 379
diabetes 361
Mycobacterium 341
tuberculosis 305
SDS 288
cardiovascular disease 278
hyperlipidemia 233
hypertension 204
hepatocellular carcinoma 196
carcinogenesis 190
coronary heart disease 189
coronary artery disease 184
obesity 166
breast cancer 165
Steroids 162
stroke 155
Alzheimer's disease 155
carcinoma 149
dyslipidemia 138
myopathy 135
cold 131
Smith-Lemli-Opitz syndrome 129
ACP 124
plaque 120
ischemia 114
myocardial infarction 103
hyperhomocysteinemia 102
pheochromocytoma 102
PCC 99
leukemia 88
depression 87
type 2 diabetes 86
tumor growth 86
epididymis 84
external genitalia 83
malaria 77
methemoglobinemia 73
mole 72
mole 72
metabolic syndrome 71
Klebsiella 70
dehydration 69
SEM 67
neuroblastoma 65
MCF 64
seminal vesicles 64
adenocarcinoma 62
fatty liver 61
iron deficiency 58
tumorigenesis 57
renal disease 57
hyperglycemia 57
vascular disease 55
FAS 52
colorectal cancer 52
osteoporosis 51
lung cancer 51
acne 50
heart failure 50
Parkinson's disease 49
mental retardation 48
mental retardation 48
NAME 46
AGA 46
melanoma 45
gallstones 44
uterus 43
erectile dysfunction 43
colon cancer 43
multiple sclerosis 43
epilepsy 43
asthma 42
Chagas 41
polycystic ovary syndrome 41
anemia 40
malnutrition 40
PDB 40
leishmaniasis 39
gynecomastia 38
renal failure 37
liver disease 37
infectious diseases 37
HIV 35
glioma 34
myocardial ischemia 34
West 34
chlorosis 34
myositis 33
herpes simplex 32
dementia 32
sepsis 32
proteinuria 32
metastases 32
cholera 32
lymphoma 32
tumor progression 31
chronic renal failure 31
heart disease 31
aggression 31
Brown 30
sepsis 30
cognitive impairment 29
Prostate Cancer 29
fits 28
PGA 28
schizophrenia 28
cholestasis 28
hyperandrogenism 27
squamous cell carcinoma 27
cataract 26
homocystinuria 26
acute myeloid leukemia 26
pancreatic cancer 25
Evans 24
infertility 24
hepatitis 24
metabolic disorder 24
rheumatoid arthritis 24
gastric cancer 23
PSA 23
nephrotic syndrome 23
Yersinia 23
dysplasia 23
virus infection 23
hyperlipoproteinemia 22
CHS 22
testicular feminization 22
neuropathy 22
multiple myeloma 22
deep vein thrombosis 21
hyperinsulinemia 21
urethra 21
AIDS 21
hepatitis C 21
enzyme deficiency 21
systemic lupus erythematosus 21
endometrial cancer 21
hypothyroidism 21
immunodeficiency 21
congenital adrenal hyperplasia 21
folate deficiency 20
PAL 20
suicide 20
preeclampsia 20
arteriosclerosis 20
scrotum 20
cirrhosis 19
influenza 19
peripheral neuropathy 19
osteosarcoma 19
acute myocardial infarction 19
non-small cell lung cancer 19
diabetic neuropathy 18
cornea 18
diabetic retinopathy 18
more...
Symptom
starvation 117
masculinization 79
weakness 62
pain 54
seizures 51
cyanosis 41
myalgia 36
headache 27
anesthesia 25
fatigue 25
hyperoxia 21
diarrhea 19
acidity 15
collapse 15
agitation 15
Lower urinary tract symptoms 14
exhaustion 14
hypotonia 13
hepatomegaly 13
tremor 12
ataxia 10
overweight 10
nausea 10
thinning 9
HSA 9
prostatism 9
flushing 8
abdominal pain 8
anorexia 7
angina 7
dysuria 7
respiratory distress 7
constipation 6
urinary frequency 6
hypothermia 6
insomnia 6
analgesia 6
ophthalmoplegia 5
cerebellar ataxia 5
lethargy 5
dyspnea 5
Acute urinary retention 5
vomiting 5
spasticity 5
dizziness 4
Ill 4
shortness of breath 4
dystonia 4
paraparesis 4
abdominal discomfort 4
splenomegaly 4
chest pain 4
Wind 4
discomfort 3
pelvic pain 3
discomfort 3
syncope 3
bloating 3
Decreased activity 3
Anoxia 3
dysarthria 3
nocturnal polyuria 3
hemiplegia 3
acute stress 3
hot flashes 3
chills 3
functional recovery 3
erythema 3
hemoptysis 2
cachexia 2
muscle stiffness 2
stomach pain 2
physical appearance 2
neurological disability 2
pallor 2
clonus 2
cough 2
scaly skin 2
sleepiness 2
arthralgia 2
microbial colonization 2
ENT 2
abnormal gait 2
dry eye 2
incoordination 2
disturbed balance 2
back pain 2
Noise-induced hearing loss 1
peau d'orange 1
heartburn 1
frequent urination 1
POA 1
livedo 1
hepatosplenomegaly 1
Cushingoid 1
twitching 1
neuralgia 1
Reticulocytosis 1
hunger 1
Deafferentation 1
Urinary symptoms 1
bone pain 1
hot flushes 1
spasm 1
Stinging 1
dry skin 1
physical exhaustion 1
leg pain 1
myoclonus 1
eds 1
tenesmus 1
menopausal symptoms 1
muscle cramps 1
generalized pain 1
apathy 1
CSR 1
alexithymia 1
Balding 1
Trembling 1
dysesthesia 1
No adverse effect 1
tense 1
vertigo 1
stigma 1
muscle rigidity 1
nasal congestion 1
oliguria 1
Cushingoid 1
abiotrophy 1
DNA marker 1
torticollis 1
ketonuria 1
tachypnea 1
polyuria 1
Urge incontinence 1
emaciation 1
asthenia 1
female puberty 1
male puberty 1
belching 1
snoring 1
jaundice of the skin 1
right upper quadrant pain 1
sore throat 1
iridodonesis 1
ACHE 1
polydipsia 1
arm pain 1
renal pain 1
blurred vision 1
fasciculation 1
Neuropathic pain 1
memory loss 1
Spots 1
flank pain 1
distraction 1
Mills 1
nausea and vomiting 1
voice change 1
difficulty with urination 1
more...
Drug
NADH 2548
FAD 698
THF 412
ascorbate 327
Simvastatin 260
lysine 242
Lovastatin 222
DHT 191
DHT 191
Pravastatin 184
Finasteride 182
vitamin E 120
Cardiovasc 116
Dermatol 110
MAP 99
ROS 97
Glutathione 79
Trypanothione 78
Gel 65
Kenyan 63
niacin 55
Leaf 54
Asn 53
Heme 48
Dihydrotestosterone 48
Rosuvastatin 45
CDP 45
CPR 43
Triclosan 43
Nitric Oxide 36
Dutasteride 35
Vitamin K 32
Ethanol 32
BH4 29
EE2 27
IFN-gamma 26
citric acid 24
nitroglycerin 24
pyridoxal phosphate 23
lactose 22
Isoniazid 21
Flavin 21
Mevastatin 19
Vitamin E 18
Adriamycin 18
caffeine 18
Estrogens 17
Ketoconazole 17
CS-514 16
IL-2 16
NBT 16
Gemfibrozil 16
ALA 15
ABC 15
MK-733 14
Cibacron Blue 14
Riboflavin 14
Bifidobacterium 14
NH3 14
Digitalis 14
-deoxyadenosine 13
Glycerol 13
Lipitor 13
Lipitor 13
Indomethacin 13
Ezetimibe 12
Angiotensin II 12
DNase I 12
Monit 12
Nephron 12
ICI 12
Arsenic trioxide 12
Pregnenolone 11
Carbenoxolone 11
R1881 11
EPA 11
HCG 11
CTX 10
Fructose 10
Lipitor 10
all-trans-retinol 10
Glycyrrhiza 10
Mutagen 10
Capsicum 10
ZnO 10
CaCl2 9
CaCl2 9
Vitamin A 9
PCB 9
FeCl3 9
CaCl2 9
PCP 8
ampicillin 8
Alanine 8
Lescol 8
Retinoic acid 8
Dial 8
Vitamin B 8
Dihydro 8
CAM 8
Ergosterol 8
Chlorate 8
Rosuvastatin calcium 8
Bezafibrate 7
Luteinizing 7
Tirapazamine 7
Glide 7
L-tyrosine 7
Vitamin B12 7
Galactose 6
Lescol 6
linolenate 6
Methylene blue 6
Fraction 6
Colesevelam 6
AraC 6
CSF 6
ACT 6
Tocopherol 5
CoCl2 5
Nephron 5
CoCl2 5
Isotretinoin 5
MTC 5
Cerivastatin sodium 5
Biopolymers 5
DEX 5
Crystal Violet 5
ADR 5
Pentaerythritol tetranitrate 5
Podophyllum 5
Tropinone 5
Trilostane 5
Cerivastatin sodium 5
Clofibrate 5
Reserpine 4
Epristeride 4
Auranofin 4
TAT 4
Ponalrestat 4
Diurnal 4
TAK 4
Taxol 4
CTX 4
Guanidine 4
NAG 4
HCH 4
Parkin 4
Parkin 4
Spectrum 4
Guanidine 4
Fragment 4
Sodium nitroprusside 3
Rutin 3
G418 3
beta-Galactosidase 3
Sulphasalazine 3
9-THC 3
Growth hormone 3
AZT 3
more...
Enzyme
CPR 699
catalase 619
superoxide dismutase 596
diaphorase 511
peroxidase 406
NQO1 367
glutathione peroxidase 339
glutathione reductase 318
nitrate reductase 299
alcohol dehydrogenase 294
nitrate reductase 293
nitrate reductase 293
nitrate reductase 291
nitrate reductase 289
nitrate reductase 289
complex I 281
ATPase 279
nitrite reductase 269
nitrite reductase 266
demethylase 265
nitrite reductase 257
succinate dehydrogenase 250
HSD 242
nitrogenase 235
glutathione S-transferase 234
aldose reductase 206
3-hydroxy-3-methylglutaryl-CoA reductase 201
ribonucleotide reductase 197
xylitol dehydrogenase 193
xylitol dehydrogenase 189
peroxiredoxin 189
11beta-hydroxysteroid dehydrogenase 186
NADPH-diaphorase 182
ribonucleotide reductase 177
thioredoxin reductase 177
lactate dehydrogenase 176
glucose-6-phosphate dehydrogenase 168
NADH-cytochrome b5 reductase 166
dihydrofolate reductase 161
adrenodoxin reductase 157
diaphorase 157
NO synthase 153
3-hydroxy-3-methylglutaryl coenzyme A reductase 148
chalcone synthase 143
mitogen-activated protein kinase 142
trypsin 138
cytochrome oxidase 135
alkaline phosphatase 130
NADPH oxidase 129
CYP3A4 119
cholesterol acyltransferase 119
NADPH oxidase 118
hydrogenase 117
luciferase 117
hydrogenase 116
NADH dehydrogenase 116
succinic dehydrogenase 114
aldehyde reductase 111
aldehyde reductase 109
protein kinase 108
ACS 107
creatine kinase 104
aldehyde reductase 104
aldehyde dehydrogenase 99
carbonyl reductase 97
acid phosphatase 94
xanthine oxidase 87
farnesyltransferase 83
formate dehydrogenase 82
aryl hydrocarbon hydroxylase 81
alanine aminotransferase 81
ERK 81
nitrous oxide reductase 79
AMP-activated protein kinase 78
heme oxygenase 77
methionine synthase 77
aspartate aminotransferase 76
formate dehydrogenase 76
formate dehydrogenase 76
CYP7A1 75
flavin reductase 75
NOS 75
anthocyanidin synthase 74
chalcone isomerase 74
fumarate reductase 74
ascorbate peroxidase 73
methionine synthase 71
acetyl-CoA carboxylase 70
aldehyde dehydrogenase 70
methane monooxygenase 68
xylulokinase 68
dehydroascorbate reductase 67
protein kinase C 67
SOR 67
malate dehydrogenase 67
aldehyde dehydrogenase 65
proteasome 65
lipoprotein lipase 65
HMG-CoA synthase 64
caspase-3 63
APC 62
aldehyde dehydrogenase 62
aldehyde dehydrogenase 62
laccase 61
RNA polymerase 61
ferredoxin reductase 61
glyceraldehyde-3-phosphate dehydrogenase 60
reverse transcriptase 59
sulfite reductase 59
sulfite reductase 58
prostate-specific antigen 58
lipase 58
5alpha-reductase 57
PAL 57
beta-galactosidase 57
flavanone 3-hydroxylase 57
5alpha-reductase 57
sulfite reductase 56
disulfide reductase 55
thymidylate synthase 54
azoreductase 53
glucose-6-phosphatase 53
glyceraldehyde-3-phosphate dehydrogenase 53
glutamine synthetase 52
tyrosinase 52
biliverdin reductase 51
ATP synthase 50
gamma-glutamyl transpeptidase 49
glucose dehydrogenase 49
APS reductase 49
ECH 48
beta-ketoacyl reductase 48
sulfite oxidase 48
glyceraldehyde-3-phosphate dehydrogenase 47
MDR 47
glyceraldehyde-3-phosphate dehydrogenase 45
sulfite oxidase 45
glyceraldehyde-3-phosphate dehydrogenase 45
glycerol-3-phosphate dehydrogenase 45
ACE 45
transhydrogenase 45
pyruvate dehydrogenase 45
phosphodiesterase 44
glycerol-3-phosphate dehydrogenase 44
soluble epoxide hydrolase 44
calcineurin 44
PARP 43
enoyl-ACP reductase 43
UDP-glucuronosyltransferase 43
enoyl-ACP reductase 42
cystathionine beta-synthase 42
protochlorophyllide oxidoreductase 42
5'-nucleotidase 42
lipoxygenase 41
isocitrate dehydrogenase 41
TOR 41
KAT 39
citrate synthase 39
MsrA 38
15-hydroxyprostaglandin dehydrogenase 38
more...
Compound
NADPH 3885
NADPH 3882
NADH 2548
oxygen 2015
Dec 1946
DNA 1694
CoA 1519
iron 1450
NADP 1242
NAD 1102
nitric oxide 1004
HMG-CoA 979
phosphate 970
hydrogen 922
NAD 918
glucose 917
water 858
Clin 780
sodium 770
nitrogen 746
sulfate 725
acetate 723
FAD 700
cysteine 663
nitrate 650
ATP 591
GSH 565
GSH 565
nicotinamide 526
arginine 454
ethanol 449
xylose 448
FMN 448
methionine 430
His 411
copper 393
ammonium 349
lysine 349
CO2 342
aldehyde 338
methane 326
calcium 325
hydroxide 315
SDS 312
tyrosine 311
salt 310
aldehyde 298
H2O2 285
Cholesterol 263
galactose 260
alanine 258
glycerol 255
molybdenum 253
ubiquinone 253
pyridine 251
DHT 237
ADP 236
homocysteine 231
ADP 225
DMSO 223
ADP 222
glutamate 220
zinc 214
glutaryl-CoA 212
serine 198
pentose 184
alcohol dehydrogenase 182
Phe 181
NH2 181
ammonia 177
Cardiol 176
DEAE 175
androstane 174
GSSG 171
aniline 166
potassium 165
AMP 154
cyanide 154
Lovastatin 154
Atorvastatin 152
proline 150
leucine 146
EDTA 145
EDTA 144
pyrene 144
selenium 143
Testosterone 142
APS 141
ubiquinol 141
Nitrite 141
Testosterone 141
methanol 140
threonine 139
N2O 137
Nitrite 137
pentose 136
pentose 136
pentose 136
acetyl-CoA 128
nickel 127
Asp 125
Pravastatin 120
Gly 120
tryptophan 118
Triton X-100 118
tryptophan 113
tryptophan 111
tryptophan 111
Ferredoxin 110
chromium 108
hydroxylamine 106
hydroxylamine 105
PEG 104
UDP 104
chromate 103
urea 100
manganese 97
hydroquinone 96
cadmium 95
ACS 95
ACS 95
acetic acid 93
phenol 91
Guo 89
Coenzyme A 89
TSH 86
glutamine 85
Mg2+ 85
cAMP 84
Progesterone 83
retinoic acid 82
bromide 82
2-oxoglutarate 82
Statin 79
cobalt 78
MVA 78
benzene 77
Vitamin D 77
dihydrofolate 77
Arsenic 74
CoQ 74
Thioredoxin 73
Fluvastatin 72
MTT 72
GTP 72
Ile 71
Androgen 71
creatinine 71
adenosylmethionine 71
vinyl 70
superoxide radical 69
aldosterone 69
malonyl-CoA 69
NO3 67
formaldehyde 66
Biliverdin 66
formaldehyde 65
ACTH 64
GABA 64
GABA 64
more...