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Query: UNIPROT:Q86TM3 (cage)
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A field investigation was conducted to study the thermoregulatory responses in nine Japanese macaques (Macaca fuscata) living in a snowy mountain area, Jigoku-Dani (Hell Valley, about 1,000 m above sea level) in Shiga Heights in central Japan in late January 1975. At about the same time, a laboratory study was made on four Japanese macaques reared in mild climate in an outdoor cage in Inuyama City. In the Hell Valley (HV) monkeys, no significant change in metabolic rate was observed at Ta between -1.4 and 28.3 degrees C, while the rectal temperature was maintained at normal level. In the cold environment, the skin temperatures of HV monkeys were significantly higher than those of the monkeys living indoors previously studied. Similar patterns of metabolic and thermal responses were observed in Inuyama monkeys living outdoors, but to a lesser degree. The hair on the back and abdomen in the HV monkeys was significantly longer than that of Iuyama monkeys living indoors. It is suggested that the thick fur of HV monkeys may account for, if not all, the thermoregulatory responses of the Japanese macaque in snowy mountain areas.
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PMID:Thermoregulation of the Japanese macaque living in a snowy mountain area. 41 Sep 88

Isolated-housing conditions (a single mouse in cage) have been reported to induce various changes in physiological and behavioral characters of mice comparing with collective-housing conditions. However, the effect of age and sex has not been studied in detail. In this report, the young (8 or 11 weeks old) and the mature (29 weeks old for male and 32 weeks for female) of both sexes were comparatively studied on the response to isolation. The duration of isolation was 12-13 weeks. Significant differences were seen in body weight, weights of fur and interscapular adipose tissue, and weight of adrenals in male, and the difference in weight of adrenals was more outstanding in the young than in the mature. In female, only weight of ovaries differed significantly between the isolation and the collective groups, and the difference prevailed in the young than in the mature. The heavy body weight with fat deposition and small adrenals in the isolated male is not consistent with the results on the isolated male rat (Hatch et al. 1965). Small ovary in the isolated female is a similar finding to reports on mice (Weltman et al. 1962) and on rats (Hatch et al. 1965).
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PMID:Effects of isolation on mice in relation to age and sex. 120 5

We tested the hypothesis that loose grass hay as a supplement to a pelleted diet reduces fur chewing in rabbits. Weanling rabbits (n = 315) were given one of three diets ad libitum: a control, pelleted diet, the pelleted diet containing 20% (wt/wt) hay meal or the pelleted diet plus loose hay. Fur chewing was assessed indirectly by blind scoring of the extent of alopecia in live rabbits and the amount of gastric hair after slaughter. Rabbits given either loose hay or the diet pellets containing hay displayed significantly less alopecia on the back and sides than control rabbits did. Loose hay, but not the pellets containing hay, completely prevented the development of alopecia on the forehead. The provision of loose hay as supplement to the control diet pellets significantly reduced the amount of gastric hair, whereas inclusion of hay meal into the pellets had no effect. It is concluded that supplemental loose hay prevents rabbits from pulling off fur from the forehead of cage mates. This effect of hay might be related to satisfaction of a craving for nibbling.
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PMID:[Supplementary hay reduces fur chewing in rabbits]. 146 40

The influence of activity upon the structure and properties of articular cartilage has been examined in two populations of fur-bearing animals. Morphological changes in cartilage of the caged animals were noted. Friction was mentioned in a vibrotribometer and it was noted that the caged animals exhibited a lower friction coefficient than the free-moving animals. In both cases the friction initially increased with age, reaching a maximum after about three years. It is concluded that prolonged hypokinesis associated with a cage-breeding regime acts like a mechanical stress factor which stimulates the development of degenerative changes in cartilage.
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PMID:Morpho-tribo-mechanical characteristics of the articular cartilage in animals under conditions of hypokinesis. 167 83

Effects of cage size, sex and social status on body growth and fur quality of juvenile, growing polecats (Mustela putorius) were studied under farm conditions. No significant differences in growth rate or fur quality parameters between various female groups were found. In males, animals housed by threes within a cage produced lowest final body mass and shortest pelt lengths. The best productive result was found in group where 2 males and 2 females were kept together in large-sized cages. In both sexes, social status did not produce any significant differences in body growth or fur quality parameters. The results support the conclusion that also other than the conventional one-male and one-female combination can be used to produce animals of big body size and long pelts.
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PMID:Effects of group and sex combination on productive performance of farmed polecats (Mustela putorius). 235 48

Behavioral reactions induced in the rat by microinjections of a gamma-aminobutyric acid (GABA) antagonist (picrotoxin; 25 and 50 ng in 0.25 microliter) into the midbrain periaqueductal gray matter were measured in an open-field test and when the animal was confronted by a conspecific introduced into its cage (i.e. resident-intruder paradigm). In the open-field, microinjections of picrotoxin significantly increased backward locomotion while decreasing self-grooming. In the resident-intruder paradigm, microinjections of picrotoxin selectively increased defensive reactions (defensive uprights, defensive sideways, retreat) while offensive behaviors were rather reduced. In addition, the actual nature of the effects was found to depend upon the intruder's relative position. Defensive reactions were significantly increased when the partner was on the side contralateral to the injection site, whereas social approach behaviors (fur investigation, anogenital investigation) were decreased when the partner was located on the ipsilateral side. These data suggest the involvement of GABAergic synapses within the midbrain periaqueductal gray matter in the control of intraspecific defensive behaviors in the rat.
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PMID:Elicitation of intraspecific defensive behaviors in the rat by microinjection of picrotoxin, a gamma-aminobutyric acid antagonist, into the midbrain periaqueductal gray matter. 369 19

Growth, body composition and hair coat parameter variations were evaluated in farmed raccoon dogs (Nyctereutes procyonoides) reared in a conventional two animals -in-cage-system. Daily rate of body weight gain (BWG) of litters very significantly (p less than 0.001) correlated with their time of birth (r = 0.879); the later in spring they were born the faster they gained weight. Final body weight (FBW) of the whelps was to be predicted from their body weight (BW) in early August (r = 0.689). There was no significant correlation between litter size and FBW, BWG or daily rate of BWG. Social competition for food produced great variation in FBW of the animals; the difference between the heavier and lighter raccoon dogs within a cage averaged 1.2 kg (p less than 0.001). Except in FBW and obesity index, there was no significant differences in other parameters between these social groups. Social status within a cage explained only 3.6% of the pelt quality variation while it could explain 52% of the BW variation. Litter explained 36% of the pelt quality, whereas it could explain 4.9% of the BW variation only. Social status and litter did not show any significant two-way interactions. Pelt weight very significantly (p less than 0.001) correlated with pelt quality (r = 0.48) and mass (r = 0.55). Also mass very positively (p less than 0.001) correlated with pelt quality (r = 0.82), indicating that the subjectively estimated pelt quality, in fact, can be derived directly from its weight. We conclude that differences in growth parameters and fur characteristics are mainly produced by social and hereditary factors, respectively.
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PMID:Growth and fur parameter variations of farmed raccoon dogs. 408 58

White mice used for protection tests with pertussis vaccines when marked with fuchsin before challenge showed reduced survival rates compared with their equally treated but unmarked cage mates. The fuchsin used had been dissolved in denaturated alcohol. On account of the small amounts of marking material applied, there was probably no direct toxic effect. Further methods of marking have then been studied in this delicate test system. Contrary to expectations the marking with picric acid solution showed no adverse effect at all. The shearing of an area of the fur, however, resulted in an even more detrimental effect than the use of fuchsin. The clipping of the top of one ear rested below the level of significance. Most probably the marked mice were neither affected adversely by the handling when marked nor by an actual chemical or mechanical impairment, but by the initiation of stress induced by the majority of their unmarked cage mates. At any rate, a possible influence of the marking of animals on the result of test procedures should be carefully considered.
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PMID:[Effect of marking laboratory animals on the results of pertussis vaccine potency tests]. 685 46

Preweanling rats, 15 days of age, were placed in an unfamiliar cage containing 1 of a variety of surrogate conspecific stimuli. The surrogate stimuli consisted of a rat-sized aluminum tube covered with soft fluffy synthetic fur, a tanned rat pelt, felt, and an aluminum sheet. The surrogate was either maintained at ambient temperature or heated to body surface temperature (37 degrees C). The 1st experiment revealed that both furriness (length and softness of fur) and temperature of the surrogate stimulus are important determinants of conspecific aggregation (huddling). The 2nd experiment demonstrated that preference for the soft, fluffy surrogate was not mediated by temperature conservation by showing that the same huddling behavior was obtained when ambient temperature was raised to thermoneutrality (33 degrees C). The final experiment demonstrated that amphetamine restricted the range of surrogate stimuli that elicited huddling in the preweanling rat. The finding that amphetamine produces a steeper generalization gradient of approach to surrogate stimuli further confirms our previous hypothesis that amphetamine canalizes arousal toward salient environmental stimuli. These findings have implications for the use of amphetamines to treat hyperkinetic children.
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PMID:Canalization of arousal in the preweanling rat: effects of amphetamine on aggregation with surrogate stimuli. 720 50

In a number of successive tests, grooming, swimming, and eating behaviors of decorticate rats were reexamined by evoking the behaviors in various circumstances (stimulus conditions). The rats showed normal-length grooming sequences during spontaneous home cage grooming; when grooming was elicited by removing the rats from their home cage and soaking their fur by a brief swim, grooming-sequence length was abbreviated. In cold (18 degrees C) water, they swam well and with exaggerated vigor and frequently inhibited forelimb movements; in warm (37 degrees C) water, they swam poorly and paddled with all four limbs. To eat small pieces of food, they sat up and used their forepaws as do normal rats, but they frequently dropped the food; they did not use their forepaws to eat large pieces of food. When given powdered food, they first tried to grasp it in their mouth while they scratched at the floor surface with their front limbs; thereafter, they became increasingly proficient in licking it up. Thus, in a narrow range of stimulus conditions, decorticate rats can make movements resembling those of normal rats. They also improve with practice in some (eating powdered food) but not other (forepaw immobility, eating large food pellets) tasks. The study shows that in order to elucidate the role of the cortex in control of motor behavior, it is necessary to obtain "behavior profiles" of each behavior by testing the animals repeatedly and under widely varying test conditions.
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PMID:Environmental constraints on motor abilities used in grooming, swimming, and eating by decorticate rats. 730 30


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