Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UNIPROT:Q86TM3 (cage)
 29,987 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The purpose of this paper was to study the frequency of alcohol abuse among injured patients between 15 and 64 years of age. This prospective study was made during a 6-week period in the autumn of 1983. The sample consisted of 166 patients (6.8 per cent of the total number of injured patients during the period of study). The patients were interviewed and one part of the questionnaire took the form of four CAGE questions. Among these 166 patients, 31.3 per cent were CAGE positive. Of these alcohol abusers, four-fifths were male and one-fifth female. CAGE-positive patients had elevated S-GGT and S-ASAT in 44 per cent of cases and elevated S-ALAT in 24 per cent. The large number of heavy drinkers found are an important target of alcohol education.
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PMID:The assessment of alcohol abuse among injured patients. 377 Sep 41

It is well-known that early diagnosis in addiction leads to a better outcome and prevents psychosocial and medical illness and disability as well as costs. It would be important to have a gold standard for the diagnosis for alcoholism because of the consequences of this diagnosis for both the patient and the physician. In the last 15 years there were world-wide efforts to find biological markers for alcoholism and alcohol abuse. The results, however, were rather poor. With the exception of the relatively new and expensive CDT TEST (Carbohydrate-deficient transferrin) and some changes in established questionnaires (shortenings) we have used the same screening tests for decades. The relationship between the patient and the physician, a detailed medical history and experience of the physician cannot be replaced by tests. The Plinius Major Society recommends in its Guidelines the CAGE questionnaire. In medical settings and in primary care the MALT or AUDIT are more informative. As laboratory markers the Plinius Major Society still recommends: gamma-GT, MCV, GOT/GPT (ASAT/ALAT) and CDT. These tests are only useful if normal values of the particular laboratory are given.
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PMID:[Markers for excessive alcohol use (screening)]. 1080 74