Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:Q86TM3 (
cage
)
29,987
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The purpose of this study was to assess the relationship between attendance at meetings of Alcoholics Anonymous (AA) and follow-up status in a sample of prison inmates. Subjects (N = 102) were administered three self-report measures of alcoholism: the MAST,
CAGE
, and Rosett Quantity-Frequency tests. AA attendance during incarceration was recorded. One-year follow-up status, ranging from transfer to a more secure facility to discharge from the prison system, was used as an outcome indicator. ResuLts revealed that 56% of the subjects met the criteria for alcoholism on at least one measure, and that scores on the alcoholism measures were significantly correlated with AA attendance. Thus, the most severe alcoholics were the best AA attenders. The hypothesis that greater AA attendance would predict follow-up outcome was not confirmed. However, the extent of drinking reported prior to admission (average alcohol quantity per week) was related to security status at 1-year follow-up. The greater the drinking quantity, the more likely the inmate was to be in a more secure facility. Possible explanations for the findings and the need for a longer follow-up period are discussed.
Am J Drug
Alcohol Abuse
1988
PMID:Alcoholism, Alcoholics Anonymous attendance, and outcome in a prison system. 323 82
The efficacy of the
CAGE
alcoholism screening test, when used as a part of a much larger health and social history questionnaire, was assessed in a family medicine residency clinic by retrospectively studying 155 charts of randomly selected adult patients. The rate of
problem drinking
, as determined by the
CAGE
, was then compared with the rate found in other studies using the
CAGE
questionnaire. The
CAGE
responses were also compared with other information in the patients' charts to assess how frequently this screening test might support a diagnosis of
problem drinking
. The incidence of
problem drinking
identified by the
CAGE
was 3.2 percent, compared with the expected 9.8 percent level (P = .0039). The
CAGE
questionnaire proved to be no better than a simple self-report of alcohol consumption (which demonstrated an incidence of 4 percent), and failed to identify two patients with histories of
alcohol abuse
as noted in their charts.
CAGE
, when used as a part of a larger health questionnaire, thus failed to identify the anticipated number of patients with drinking problems.
...
PMID:Efficacy of an alcoholism self-report questionnaire in a residency clinic. 359 80
The internal consistency reliability and criterion-related validity of the Michigan Alcoholism Screening Test (MAST) (N = 90), Mortimer-Filkins Questionnaire (MFQ) (N = 253) and
CAGE
(N = 375) were examined. Respondents were convicted of driving while intoxicated (DWI) and were assessed for the significance of their drinking problem at 34 DWI assessing agencies. Counselor decisions served as the criterion measure and were considered to be independent of the test scores. The finding revealed that counselors identified lower rates of
problem drinking
than are generally found to exist in this population. The MAST performance, although statistically impressive, was believed to be mediated by the low rate of counselor-identified problem drinkers. The MFQ, more moderate in its performance, shows promise for improvement based on recommended modifications.
CAGE
findings suggest little support for its use as a single index of
problem drinking
with this population. However, it would appear to be a statistical asset to the item pool of a more comprehensive screening inventory. The criterion used in the study did not provide a satisfactory range of
problem drinking
with which to evaluate the adequacy of these instruments as wide-range assessment inventories. The social-legal mandate to reduce the incidence of DWI will require not only more comprehensive definitions of
problem drinking
but more extensive study of repeat offenders for the identification of other subgroups as well.
...
PMID:Reliability and validity of the MAST, Mortimer-Filkins Questionnaire and CAGE in DWI assessment. 366 78
In several retrospective studies, alcoholic women have reported menstrual problems significantly more often than nonalcoholic women. There is no information, however, comparing the prevalence of
alcohol abuse
in women who receive periodic gynecologic care and those who seek care for menstrual disorders such as the premenstrual syndromes. This question was studied in two private practice settings. Women seeking periodic care were obtained from a suburban, general gynecology practice. Women seeking treatment for premenstrual syndrome (PMS) were obtained from a practice that specialized in the care of PMS. Ninety-five patients with PMS and 147 patients seeking periodic care were screened with the
CAGE
questions--a mnemonic for attempts to Cut back on drinking, being Annoyed at criticism about drinking, feeling Guilty about drinking, and using alcohol as an Eye-opener. Women who gave affirmative responses to one or more of the
CAGE
questions were evaluated for the presence of
alcohol abuse
. In the women seeking periodic care, 33% were
CAGE
positive and 12% were alcohol abusers. In the PMS practice, 51% were
CAGE
positive and 21% were alcohol abusers.
Alcohol abuse
is a common problem in gynecologic practice. Women who seek medical care for PMS are at much greater risk to be alcohol abusers.
...
PMID:Alcohol abuse in women seeking gynecologic care. 373 53
The purpose of this paper was to study the frequency of
alcohol abuse
among injured patients between 15 and 64 years of age. This prospective study was made during a 6-week period in the autumn of 1983. The sample consisted of 166 patients (6.8 per cent of the total number of injured patients during the period of study). The patients were interviewed and one part of the questionnaire took the form of four
CAGE
questions. Among these 166 patients, 31.3 per cent were
CAGE
positive. Of these alcohol abusers, four-fifths were male and one-fifth female.
CAGE
-positive patients had elevated S-GGT and S-ASAT in 44 per cent of cases and elevated S-ALAT in 24 per cent. The large number of heavy drinkers found are an important target of alcohol education.
...
PMID:The assessment of alcohol abuse among injured patients. 377 Sep 41
The social network, family functioning, and health-protective behaviors of 77 osteoarthritis patients treated for 12 weeks by a multidisciplinary team were assessed. Measures included assessments of social network using components of the OARS, family satisfaction using the APGAR, family cohesion and adaptability using the FACES II,
alcohol abuse
using the
CAGE
, and indicators of health-protective behaviors. Participants were generally socially active, socially integrated, and satisfied with family relationships. Reported health-protective behaviors were low, indicating the need for assistance in improving preventive health practices. Few of the patients appeared to be at risk for alcoholism. Improvements in pain and activities of daily living were not correlated with changes in social functioning. Social functioning appeared to be relatively stable and not altered by short-term improvements in osteoarthritis. Social workers can play an important role in facilitating individual and family adjustment to the limitations imposed by osteoarthritis and in the rehabilitation process for osteoarthritis patients.
...
PMID:Psychosocial aspects of the multidisciplinary assessment of osteoarthritis. 382 97
The information on drinking habits contained in medical records with that obtained through the
CAGE
alcoholism screening test was compared for 124 inpatients of a teaching general hospital. This survey was followed by testing the possibility of introducing the
CAGE
test into the routine clinical interview. A second analysis of 110 medical records performed 2 months later indicated the failure of this attempt, as the general pattern of information on drinking habits remained unaltered and characterized by either no information at all or information that was too ambiguous to be of clinical value. Among the different hypotheses that could account for the negative results is the possibility that physicians are not sufficiently informed on the wide spectrum of clinical disorders associated to
alcohol abuse
. Another important factor is the lack of motivation shown by attending physicians to detect less obvious cases of alcohol dependence as they feel pessimistic about dealing with this condition.
...
PMID:An attempt to improve the identification of alcohol-dependent patients in a teaching general hospital. 406 10
In a 69 year-old female patient who had been a pet bird enthusiast, cryptococcosis of the central nervous system was surprisingly established as cause of death at postmortem. Clinically, a diagnosis of cirrhosis of the liver associated with atypical coma hepaticum had been suspected. Apart from damage due to
alcohol abuse
, no other underlying disease could be found. The fecal matter of a budgerigar (Melopsittacus undulatus) has been suggested as the probable source of infection. Using Guizotia abyssinica creatinine agar, Cryptococcus neoformans could be isolated from dry fecal matter collected from the bird
cage
. In a pet shop in the neighbourhood of the patient's home, fecal matter from various pet bird species was collected. Using the same method, examination also revealed the presence of Cr. neoformans. Contrastingly, masses of pigeon manure found in the garret of the patient's house did not contain Cr. neoformans. The epidemiological significance of the fecal matter of pet birds as a habitat for Cr. neoformans is discussed.
...
PMID:[Fatal cryptococcosis in a bird fancier. A clinical case report on pathology, diagnosis and epidemiology of cryptococcosis]. 636 34
One hundred forty-seven adult patients seeking care at a university family practice center were screened for alcoholism. Approximately one half were given the Michigan Alcoholism Screening Test (MAST), and the rest were interviewed by a trained interviewer who administered the MAST and a shorter questionnaire (the
CAGE
) and used her overall clinical impression to gauge their likelihood of being alcoholic. The two groups were demographically similar, as were the results of the screening. There were 28 patients (19.1 percent) with a MAST score greater than 5, and 24 patients (16.3 percent) were thought to be alcoholic. The prevalence of alcoholism was much higher in men (P less than .001), but no other demographic differences were found. Twenty-four clinic charts of patients with alcoholism identified in the study were reviewed for evidence of physician awareness of
alcohol abuse
, but in only 12 was alcohol use mentioned at all, and in only two was alcoholism diagnosed. These findings are consistent with prior published reports of incidence of alcoholism in other settings.
...
PMID:Prevalence of alcoholism in a family practice center. 672 32
We reviewed the initial history, obtained by the orthopaedic house staff, of each of eighty-seven patients who were consecutively admitted to an acute orthopaedic-surgery service. A diagnosis of alcoholism was made by the house staff in only one of every ten patients who had been identified as having symptoms of alcohol addiction in a previous study.
Alcohol abuse
was identified in only five of every ten such patients. Of the orthopaedic patients in this sample who had been shown to be abusing alcohol, 37 per cent were neither suspected nor diagnosed as abusers by the orthopaedic house staff. We recommend the use of a brief screening interview (
CAGE
) to increase diagnostic effectiveness in this area, and discuss the clinical usefulness of an early diagnosis of alcoholism among orthopaedic surgical patients.
...
PMID:Alcoholism assessment on an orthopaedic surgery service. 708 98
<< Previous
1
2
3
4
5
6
7
8
9
10
Next >>