Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:Q7LGC8 (
HSD
)
3,196
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
HSD
3196
Mol
355
ANOVA
310
HSD1
242
3 beta-HSD
225
reductase
225
HSD2
222
Sep
217
P450scc
168
17 beta-hydroxysteroid dehydrogenase
164
3 beta-hydroxysteroid dehydrogenase
163
HDL
158
aromatase
155
cytochrome P450
145
StAR
136
insulin
126
NAD
125
P450
117
Leydig cell
109
steroidogenic acute regulatory protein
107
NADPH
98
mineralocorticoid receptor
96
FSH
95
microsomal
92
NADP
87
ACTH
86
P450c17
78
glucocorticoid receptor
74
Gen
74
delta 4
69
androgen receptor
69
CYP11A1
62
17beta-hydroxysteroid dehydrogenase
59
NADH
59
NAD+
58
Aromatase
53
endoplasmic reticulum
52
HSD-1
50
C17
50
cytochrome
48
more...
Disease
hypertension
140
Steroids
84
tumor
82
obesity
74
cancer
64
breast cancer
61
diabetes
54
SEM
38
GSH
35
uterus
32
epididymis
31
polycystic ovary syndrome
30
infertility
29
prostate cancer
28
carcinoma
26
congenital adrenal hyperplasia
25
metabolic syndrome
25
Cushing's syndrome
24
type 2 diabetes
23
depression
22
Testes
19
MCF
18
SDS
17
NSD
16
hypercortisolism
15
essential hypertension
15
choriocarcinoma
14
osteoporosis
14
Placenta
14
hyperglycemia
14
glucose intolerance
14
cholera
13
wasting
13
aldosteronism
13
adenoma
12
endometriosis
12
IPS
12
cold
12
hepatocellular carcinoma
11
external genitalia
11
more...
Symptom
masculinization
25
pain
12
fatigue
11
anesthesia
10
overweight
5
acidity
4
hypothermia
3
headache
3
agitation
3
seizures
3
flushing
2
polydipsia
2
starvation
2
respiratory distress
2
back pain
2
Decreased activity
2
Cushingoid
2
dystonia
2
Cushingoid
2
polyuria
2
acute stress
2
exhaustion
2
discomfort
2
CSR
1
HSA
1
Tissue sensitivity
1
muscle stiffness
1
distraction
1
splenomegaly
1
hepatomegaly
1
loss of balance
1
male subfertility
1
tremor
1
voice change
1
lethargy
1
thinning
1
discomfort
1
hunger
1
low back pain
1
weakness
1
more...
Drug
NADH
59
MAP
45
DHT
27
DHT
27
EE2
26
ROS
17
THF
17
Carbenoxolone
15
Trilostane
15
Dermatol
11
ascorbate
10
HCG
9
lysine
9
vitamin E
8
Estrogens
8
CAM
8
Ethanol
8
Glycyrrhiza
7
Forskolin
6
Pregnenolone
6
Gel
6
Dihydrotestosterone
5
Angiotensin II
5
CTX
5
Ringer's solution
5
Asn
5
ICI
5
Digitalis
5
caffeine
4
Activin
4
IFN-gamma
4
ENT
4
DEX
4
Rosiglitazone
3
Monit
3
ZnO
3
Lead acetate
3
balanced salt solution
2
Leaf
2
Ketoconazole
2
more...
Enzyme
HSD
3124
11beta-hydroxysteroid dehydrogenase
352
3beta-hydroxysteroid dehydrogenase
250
17beta-HSD
72
superoxide dismutase
60
17beta-HSD
55
cytochrome P-450scc
53
catalase
50
mitogen-activated protein kinase
40
protein kinase
35
chondroitin 6-sulfotransferase
34
renin
33
carbonyl reductase
28
glutathione peroxidase
28
ERK
25
protein kinase C
24
5alpha-reductase
21
5alpha-reductase
21
caspase-3
20
alkaline phosphatase
20
20alpha-hydroxysteroid dehydrogenase
20
peroxidase
19
glucose-6-phosphate dehydrogenase
18
sulfatase
15
reverse transcriptase
15
glutathione S-transferase
14
21-hydroxylase
13
luciferase
13
ATPase
12
collagenase
12
glutathione reductase
12
3alpha-hydroxysteroid dehydrogenase
11
chondroitin 4-sulfotransferase
10
15-hydroxyprostaglandin dehydrogenase
10
dihydrodiol dehydrogenase
10
AMP-activated protein kinase
10
prostaglandin F synthase
10
hydroxyprostaglandin dehydrogenase
9
RNase
9
adenylate cyclase
9
more...
Compound
Dec
260
water
191
NAD
173
Clin
154
sodium
142
NADP
134
aldosterone
130
NAD
125
DNA
117
NADPH
99
NADPH
98
sulfate
97
ACTH
86
salt
85
glucose
82
cAMP
73
acetate
61
NADH
59
oxygen
58
phosphate
56
DHA
49
Progesterone
43
calcium
40
androstane
39
ethanol
39
Cortisol
38
GSH
36
GSH
36
Androstenedione
34
Testosterone
32
DHT
32
hydrogen
32
Testosterone
32
nicotinamide
32
potassium
30
COS
30
LSD
29
GalNAc
26
Estradiol
25
nitric oxide
25
more...