Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:Q16795 (ubiquinone)
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Human Gene/Protein
ubiquinone 12.5
EF-hand domain-containing protein 1 12.5
NUCM 12.5
COQ10B 12.5
CABC1 protein 12.5
protein phosphatase 2A regulatory subunit A beta isoform 12.5
NDUFV2 protein 12.5
PP52 11.9
CLK-1 11.9
CABC1 11.8
DHHB methyltransferase 11.5
C1QL4 11.5
COQ3 11.5
mitochondrial malate dehydrogenase 2, NAD 11.5
MNLL 11.5
GTP-binding protein SAR1 11.5
LYRM3 11.5
PSST subunit 11.2
COQ5 11.1
COQ8 11.1
ADCK3 11.1
iron-sulfur protein 3 11.1
PSST 11.0
rab10 10.9
hDLP1 10.9
40S ribosomal protein S23 10.9
CLSTN3 10.9
ZNF205 10.9
SnuCyp-20 10.9
ZNF183 10.9
cytochrome oxidase assembly factor 10.9
NDUFB3 10.9
ubiquinone biosynthesis protein 10.9
COQ10A 10.9
ubiquitin-like modifier activating enzyme 3 10.9
COQ7 10.9
ETF-QO 10.8
TYKY 10.8
clk-1 10.7
CAT5 10.6
Ras-related protein Rab-2A 10.5
C20orf7 10.5
ATP synthase gamma chain 10.5
KIAA1391 10.5
mitochondrial ribosomal protein L12 10.5
COQ9 10.5
PDSS2 10.5
TYKY subunit 10.4
NDUFS2 10.4
NDUFS7 10.3
NDUFS3 10.3
ubiquinone-binding protein 10.2
Secernin-1 10.2
CNTD2 10.2
ETFB 10.1
HRPAP20 10.1
complex I assembly factor 10.1
complex I) 10.0
COQ2 10.0
NADH-ubiquinone oxidoreductase 9.9
ETFA 9.9
sodium/bile acid cotransporter 9.9
aquarius 9.9
electron transfer flavoprotein-ubiquinone oxidoreductase 9.8
NADH-ubiquinone reductase 9.7
C8orf38 9.7
ACN9 9.7
acyl-CoA dehydrogenase 9 9.7
rab1b 9.7
N-myc downstream-regulated gene 3 9.7
nucleotide binding protein-like 9.7
GPR172B 9.7
HO3 9.7
COQ6 9.6
NADH: ubiquinone oxidoreductase 9.6
NDUFS8 9.6
NDUFB5 9.5
transcription factor NRF 9.5
MCT13 9.5
ZFYVE9 9.5
more...
Disease
MYP5 11.5
MYP11 11.5
Complex II deficiency 10.2
SGM1 10.2
YSS 9.9
DKC 9.3
DKC 9.3
Disseminated trichosporonosis 9.3
PGL4 8.9
Cytauxzoonosis 8.4
17-alpha-hydroxylase deficiency 8.3
Miller syndrome 8.3
PGL2 8.3
Fazio-Londe 8.0
metabolic syndrome X 7.7
UMS 7.7
Complex I deficiency 7.6
Mevalonate kinase deficiency 7.3
PGL3 7.3
Pearson's syndrome 6.8
Diabetic polyneuropathy 6.6
FGD1 6.5
Leber's hereditary optic neuropathy 6.5
white muscle disease 6.4
Cerebellar atrophy 6.4
GH-secreting pituitary adenoma 6.4
FA2 6.3
cerebral degeneration 6.2
cardiofaciocutaneous syndrome 6.2
schizophreniform psychosis 6.2
AN2 6.1
GHD 6.1
piedra 5.9
Leigh syndrome 5.7
Barth syndrome 5.6
mitochondrial disease 5.5
PARK7 5.5
Familial combined hyperlipidemia 5.4
Mitchell 5.3
syndrome X 5.3
RAT 5.2
MELAS 5.2
FPP 5.2
Kearns-Sayre syndrome 5.2
CCA1 5.2
VES 5.1
hypovitaminosis 5.1
Reye 5.1
glutaric aciduria 5.1
Phototoxicity 5.1
myotonia congenita 5.0
MELAS 4.9
global aphasia 4.9
PMS 4.9
Zellweger syndrome 4.9
kidney hypertrophy 4.8
RP11 4.8
mitochondrial myopathy 4.7
MSF 4.7
ISM 4.7
legionellosis 4.5
mitochondrial encephalomyopathy 4.5
Friedreich's ataxia 4.5
neuronal ceroid lipofuscinosis 4.5
ACS1 4.4
riboflavin deficiency 4.3
RP18 4.3
IMT 4.2
LMS 4.2
paraganglioma 4.1
methylmalonic acidemia 4.1
achromatopsia 4.1
protein deficiency 4.0
MCS 4.0
myopathy 4.0
MCS 4.0
lipidosis 4.0
Murray Valley encephalitis 3.9
retinoschisis 3.9
PHS 3.9
more...
Symptom
astasia 6.6
Cold intolerance 6.4
blemishes 5.8
generalized pain 4.9
cerebellar ataxia 4.2
Decreased activity 3.5
Fluctuation 3.3
hypotonia 3.2
drooling 3.1
consciousness disturbance 2.8
muscle rigidity 2.4
ophthalmoplegia 2.4
myalgia 2.2
ataxia 2.1
exhaustion 2.1
hypocapnia 1.8
starvation 1.7
hepatomegaly 1.6
chills 1.5
collapse 1.2
hyperoxia 1.2
dry eye 1.2
dystonia 1.1
weakness 1.0
angina 0.7
insomnia 0.7
vertigo 0.7
memory loss 0.7
fatigue 0.2
cachexia 0.0
hypothermia 0.0
tremor -0.1
sleepiness -0.1
spasticity -0.1
erythema -0.2
seizures -0.2
discomfort -0.4
nausea -0.4
hypercapnia -0.4
discomfort -0.5
dizziness -0.7
Ill -0.9
overweight -1.2
stigma -1.2
functional recovery -1.2
anorexia -1.2
dyspnea -1.3
diarrhea -1.3
respiratory distress -1.7
anesthesia -2.2
vomiting -2.4
headache -3.3
pain -5.5
Drug
Mubritinib 10.2
Phenylphosphate 9.3
Duroquinone 8.9
Avobenzone 8.8
Idebenone 8.8
Hpp 8.6
Atovaquone 8.6
Atovaquone 8.2
MK-733 7.7
NADH 7.6
Pentane 7.6
Secobarbital 7.2
Demerol 7.1
Mevastatin 7.1
Tween 40 6.9
Corn oil 6.8
FAD 6.6
Demerol 6.5
Fosmidomycin 6.4
Dithranol 6.2
Fusicoccin 6.1
Malonaldehyde 5.9
Lovastatin 5.7
Flavin 5.7
Cinnarizine 5.7
Flupenthixol 5.7
Pravastatin 5.7
Ranolazine 5.6
Ranolazine 5.6
vitamin E 5.4
Vitamin K2 5.3
Riboflavin 5.2
ISP 5.2
Caspofungin 5.1
TRM 5.0
SMP 4.9
all-trans-retinol 4.9
Vitamin K 4.9
Tween 60 4.8
Simvastatin 4.8
Vitamin E 4.7
Tocopherol 4.7
ascorbate 4.5
Dihydro 4.5
RbCl 4.4
RbCl 4.4
Guanethidine 4.4
Clofibrate 4.4
Palmitoyl 4.3
linolenate 4.3
Ergosterol 4.2
Gemfibrozil 4.2
AC2 4.1
RSM 4.1
Carotenoid 4.0
Ganciclovir 4.0
SPP 3.9
Dextrose 3.9
MDM 3.8
niacin 3.8
Bosentan 3.8
Bosentan 3.8
beta-Galactosidase 3.7
Rosuvastatin 3.7
Maltose 3.7
Cibacron Blue 3.6
Citric acid 3.5
Heme 3.5
L-tyrosine 3.3
ROS 3.2
Cremophor EL 3.2
Colistin 3.1
Glycerol 2.9
Triclosan 2.9
citric acid 2.8
Glutathione 2.7
Adenosine triphosphate 2.7
Omeprazole 2.5
Capsicum 2.4
Adriamycin 2.3
more...
Enzyme
4-hydroxybenzoate transferase 11.9
EC 1.1.4.1 11.5
trans-prenyltransferase 10.9
EC 1.14.13.23 10.9
4-hydroxybenzoate decarboxylase 10.9
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 10.5
hexaprenyl diphosphate synthase 10.2
ubiquinol-cytochrome c oxidoreductase 10.0
gamma-glutamylmethylamide synthetase 9.9
malate oxidase 9.8
EC 1.1.99.16 9.5
thiosulfate dehydrogenase 9.3
4-N-trimethylaminobutyraldehyde dehydrogenase 9.3
electron transfer flavoprotein dehydrogenase 9.3
DHOdehase 9.1
dihydroorotate dehydrogenase 9.1
dihydroorotate dehydrogenase 9.1
energy-linked transhydrogenase 9.1
NADH dehydrogenase 9.0
2-hydroxyglutarate dehydrogenase 9.0
complex I 8.8
2,4-dichlorophenol hydroxylase 8.6
sulfur dioxygenase 8.3
diaphorase 8.2
fumarate reductase 8.1
membrane-bound hydrogenase 8.1
EC 5.3.3.2 8.1
thiosulfate dehydrogenase 8.1
D-sorbitol dehydrogenase 8.1
Dol-P phosphatase 8.1
isovaleryl-CoA dehydrogenase 8.0
sulfur reductase 7.9
ADP-dependent glucokinase 7.8
glycine dehydrogenase 7.8
glycine dehydrogenase 7.8
pyruvate oxidase 7.6
pyruvate oxidase 7.6
EC 1.1.1.47 7.5
succinate dehydrogenase 7.5
CPL 7.5
5'-methylthioadenosine nucleosidase 7.5
ketopantoate reductase 7.4
selenate reductase 7.4
12-oxophytodienoate reductase 7.4
MenD 7.3
1-deoxy-D-xylulose-5-phosphate synthase 7.2
mannosylphosphoryldolichol synthase 7.2
prenyltransferase 7.2
NADPH:quinone oxidoreductase 7.2
glycerol 3-phosphate dehydrogenase 7.2
prenyltransferase 7.2
glycine dehydrogenase 7.2
prenyltransferase 7.1
methanol dehydrogenase 7.1
glucose dehydrogenase 7.1
1-deoxy-D-xylulose-5-phosphate reductoisomerase 7.1
acyl-CoA dehydrogenase 7.1
CPR 7.0
m-AAA protease 7.0
succinic dehydrogenase 7.0
bidirectional hydrogenase 6.9
anthranilate synthase 6.9
PabB 6.8
glycerol-3-phosphate oxidase 6.8
sarcosine dehydrogenase 6.7
enzyme X 6.7
dolichol kinase 6.6
mevalonate kinase 6.5
transhydrogenase 6.4
dihydrolipoamide succinyltransferase 6.4
amorpha-4,11-diene synthase 6.3
cytochrome b6/f complex 6.3
lactate oxidase 6.3
squalene epoxidase 6.3
acyl-CoA dehydrogenase 6.3
proline dehydrogenase 6.2
3-hydroxy-3-methylglutaryl-CoA lyase 6.2
choline dehydrogenase 6.2
cytochrome oxidase 6.2
oxidosqualene cyclase 6.1
more...
Compound
Papyriferic acid 12.5
H6CoQ4 12.5
3,4-Dihydroxy-5-hexaprenylbenzoate 12.5
ubiquinone 12.4
solanesyl pyrophosphate 11.7
C20H26O2 11.5
Ubisemiquinone 11.5
Papyriferic acid 11.5
Redoxal 11.5
Decylubiquinone 11.2
Spheroidenone 10.9
ubiquinol 10.8
Plastoquinone 10.6
Menoctone 10.5
C10H7NO2 10.5
CoQ6 10.4
CoQ 10.4
Durohydroquinone 10.2
CoQ9 10.2
CoQ4 10.2
2-hydroxydodecanoic acid 10.1
THG 10.1
2-Heptyl-4-hydroxyquinoline-N-oxide 9.9
delta-Tocopherol 9.9
Stigmatellin 9.9
Daunomycinone 9.9
K acid 9.9
Gracillin 9.7
Coenzyme Q10 9.5
heptanamide 9.3
Spheroidene 9.3
Phenylphosphate 9.3
Benzyl Viologen 9.3
Chorismate 9.2
Dihydrolipoic acid 9.2
X 34 9.2
2-phenoxybenzoic acid 9.2
2-hydroxyhexadecanoic acid 9.2
Perillic acid 9.2
Octadecyltrichlorosilane 9.2
coenzyme Q10 9.1
phytanoyl-CoA 9.1
Dopaquinone 9.1
Solanesol 9.0
ANI 8.9
Diiodothyronine 8.9
2-hydroxynaphthoquinone 8.9
2-hydroxynaphthoquinone 8.8
5-aminovalerate 8.7
3-succinoylpyridine 8.7
Vitavax 8.7
Dolichol 8.6
Geranyl pyrophosphate 8.6
Funiculosin 8.6
2-keto-3-deoxy-6-phosphogluconate 8.5
MPDP 8.5
2,4-hexanedione 8.4
Duroquinone 8.4
Di-n-butyltin dichloride 8.4
4'-phosphopantothenoylcysteine 8.4
Adrenic acid 8.3
Tricarballylic acid 8.3
Dequalinium chloride 8.3
Isovitexin 8.2
Orcinol 8.1
heptyl 8.1
heptyl 8.1
DCIP 8.1
Antimycin 8.1
Perillyl alcohol 8.1
Perillyl alcohol 8.1
Quinone 8.0
Bendroflumethiazide 7.9
Oxmetidine 7.9
3-phenyl-1-propanol 7.8
Farnesyl diphosphate 7.8
2,6-dichlorophenol 7.8
BPQ 7.7
Cytochrome c1 7.7
Tetraphenylphosphonium 7.7
more...