Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:Q16637 (
SMA
)
8,107
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
SMA
8107
collagen
1783
smooth muscle actin
1685
Mol
807
alpha-smooth muscle actin
748
vimentin
596
fibronectin
564
SMN2
497
E-cadherin
489
Sep
483
SMN
431
CD34
330
desmin
320
Smad2
303
Smad3
279
TNF
265
CD31
243
IL-6
209
cytokine
206
type I collagen
178
catenin
169
connective tissue growth factor
144
p38
137
ERK
136
cytokeratin
132
MAPK
126
telomeric
126
ERK1
125
vascular endothelial growth factor
123
p53
122
proliferating cell nuclear antigen
121
caspase-3
117
S100
117
tumor necrosis factor
116
PDGF
113
TGF-beta
112
Ki-67
110
cage
110
AKT
110
calponin
109
matrix metalloproteinase
108
VEGF
108
EMA
107
CD68
106
Vimentin
106
MMP-2
101
PI3K
101
aspartate aminotransferase
101
albumin
100
MMP-9
97
Ang II
95
MRI
94
N-cadherin
88
glial fibrillary acidic protein
88
CTGF
87
angiotensin II
86
Bcl-2
83
CD117
83
c-kit
80
platelet-derived growth factor
78
Smad7
77
STAT3
77
p65
76
EPA
76
alanine aminotransferase
75
NRK
74
JNK
74
AE1
73
HSC
73
neuronal apoptosis inhibitory protein
71
axonal
70
ECM
69
AE3
69
superoxide dismutase
68
TLR4
66
alkaline phosphatase
65
GSH
64
AST
64
mTOR
63
COL1A1
63
more...
Disease
tumor
838
muscular atrophy
625
Spinal muscular atrophy
596
liver fibrosis
591
cancer
508
pulmonary fibrosis
295
carcinoma
167
cirrhosis
141
renal disease
135
diabetes
126
idiopathic pulmonary fibrosis
125
tumor growth
107
EMA
107
neuromuscular disorder
104
motor neuron disease
104
diabetic nephropathy
101
tumor progression
97
hypertension
88
breast cancer
88
hepatocellular carcinoma
86
ischemia
86
asthma
81
myocardial infarction
81
adenocarcinoma
74
hepatitis
70
metastases
69
atherosclerosis
69
Kugelberg-Welander
66
GSH
64
Werdnig-Hoffmann disease
64
proteinuria
58
amyotrophic lateral sclerosis
58
heart failure
53
lung disease
53
Renal fibrosis
52
sarcoma
51
liver disease
51
EMT
50
pancreatic cancer
46
tumorigenesis
44
fatty liver
42
Parkinson's disease
39
glomerulosclerosis
39
chronic liver disease
39
PSS
38
SMA II
38
cornea
38
squamous cell carcinoma
38
stroke
38
chronic renal failure
37
carcinogenesis
37
colorectal cancer
37
chronic hepatitis
36
celiac disease
35
epilepsy
34
liver cancer
34
glioblastoma
33
glioma
33
adenoma
33
lung cancer
32
melanoma
32
hepatitis C
32
renal failure
31
genetic disorder
30
uterus
29
gastrointestinal stromal tumor
29
Blocking
29
chronic pancreatitis
29
obesity
28
hyperglycemia
28
glomerulonephritis
28
gastric cancer
27
scleroderma
26
chronic obstructive pulmonary disease
26
proliferative vitreoretinopathy
25
portal hypertension
25
pancreatic fibrosis
24
coronary artery disease
24
dysplasia
24
MCF
24
more...
Symptom
weakness
197
pain
54
abdominal pain
28
hypotonia
27
respiratory distress
26
seizures
19
anesthesia
19
tremor
16
fatigue
16
thinning
15
vomiting
13
cough
13
collapse
12
hyperoxia
11
abdominal discomfort
10
dyspnea
9
epigastric pain
8
constipation
7
Scratch
7
diarrhea
7
chest pain
6
HSA
6
nausea
6
functional recovery
6
angina
5
starvation
5
back pain
5
dystonia
5
fasciculation
5
colic
4
exhaustion
4
splenomegaly
4
headache
4
regurgitation
4
acidity
4
joint stiffness
4
bradykinesia
4
hepatomegaly
4
stridor
3
Stiffness
3
syncope
3
myoclonus
3
hoarseness
3
discomfort
3
abnormal gait
3
dry eye
3
flank pain
3
Tongue fasciculations
3
discomfort
3
spasticity
3
tense
2
numbness
2
exertional dyspnea
2
hypothermia
2
Decreased activity
2
cyanosis
2
paresis
2
stigma
2
paresthesia
2
anorexia
2
excessive sweating
2
arthralgia
2
ataxia
2
nausea and vomiting
2
distraction
2
analgesia
2
Involuntary Movement
2
Ill
2
dysarthria
2
rigors
1
cerebellar ataxia
1
agitation
1
Functional constipation
1
Welt
1
CSR
1
stomach pain
1
asterixis
1
nasal discharge
1
chronic constipation
1
Postoperative pain
1
more...
Drug
ROS
60
Dermatol
46
Monit
37
MRC
30
Angiotensin II
21
Cardiovasc
18
Asthma
17
Fluorescein
16
lysine
16
BLM
12
CSF
12
ascorbate
11
Pirfenidone
10
TMS
10
CCL
9
Frontal
9
MAP
8
Ethanol
7
Sorafenib
7
Taxol
7
CAM
6
Paraffin
6
Albumin
6
IFN-gamma
6
Gel
6
Portal
6
Emodin
5
Leaf
5
Gleevec
5
Activin
5
GEO
5
IL-2
5
Imatinib
5
Simvastatin
5
Emodin
5
ADM
5
Captopril
5
lactose
5
Valsartan
4
Liraglutide
4
CaCl2
4
Retinoic acid
4
DEX
4
CaCl2
4
Diamminedichloroplatinum
4
Nephron
4
Spectrum
4
CaCl2
4
ABC
4
Vitamin A
4
Nitric Oxide
4
uPA
4
Dial
4
ACT
4
G418
4
Epigallocatechin
4
Nephron
4
NADH
4
Estrogens
3
Bevacizumab
3
TTC
3
Ouabain
3
Bortezomib
3
Spectrum
3
Gelatin
3
p75
3
ATV
3
ALA
3
3-Methyladenine
3
CTX
3
PTC
3
ETS
3
Salbutamol
3
KGF
3
Forskolin
3
Troglitazone
3
Alliance
3
ETA
3
Silica
3
Glycyrrhiza
3
more...
Enzyme
mitogen-activated protein kinase
349
ERK
322
alanine aminotransferase
171
aspartate aminotransferase
163
luciferase
124
focal adhesion kinase
123
superoxide dismutase
103
collagenase
91
protein kinase
90
caspase-3
83
alkaline phosphatase
65
AST
64
CD10
59
peroxidase
47
NADPH oxidase
43
catalase
43
NADPH oxidase
41
MEK
39
renin
39
MMP
35
reverse transcriptase
33
GSK
32
AMP-activated protein kinase
32
proteasome
28
lactate dehydrogenase
28
ACE
27
PARP
24
phosphatidylinositol 3-kinase
23
HK2
22
AMPK
21
AMPK
21
ACS
21
protein kinase C
21
ATPase
18
RNA polymerase
17
matrix metalloproteinase 2
17
glutathione peroxidase
16
trypsin
16
caspase-1
16
calcineurin
15
tryptase
14
phosphoinositide 3-kinase
14
creatine kinase
12
gamma-glutamyl transpeptidase
12
glutathione S-transferase
10
glyceraldehyde-3-phosphate dehydrogenase
10
PME
10
lysyl oxidase
10
thrombin
10
caspase-9
10
transcriptase
9
matrix metalloproteinase 9
9
MMP-3
9
NO synthase
8
glucose oxidase
8
urokinase-type plasminogen activator
7
soluble epoxide hydrolase
7
IKK
7
cdc2
7
myosin light chain kinase
7
lysozyme
7
phosphodiesterase
7
NQO1
6
lipase
6
beta-galactosidase
6
DNA methyltransferase
6
MAP
6
MEKK1
6
NOS
6
uricase
5
prolyl hydroxylase
5
hexokinase
5
heme oxygenase
5
arginase
5
alcohol dehydrogenase
5
phospholipase A2
5
aldehyde dehydrogenase
5
tyrosine hydroxylase
5
RNase
5
RNase
5
more...
Compound
Dec
488
Clin
365
DNA
267
TNF
265
glucose
231
oxygen
221
Collagen
156
creatinine
139
water
137
calcium
118
MTT
107
Vimentin
106
CCl4
101
urea
90
sodium
89
Ang II
88
nitrogen
76
ASA
72
phosphate
69
GSH
65
GSH
65
MDA
64
ANA
60
ANA
60
Hematoxylin
59
ethanol
58
hyaluronic acid
50
nitric oxide
47
arginine
44
tyrosine
41
PEG
39
acetate
38
methionine
37
iron
36
BLM
35
ATP
34
hydrogen
33
salt
32
PEG
30
dUTP
29
zinc
29
MEK
28
cAMP
27
N-acetylcysteine
26
galactose
25
sulfate
25
Angiotensin II
24
PAS
23
phosphorus
23
potassium
23
ALP
23
Cereb
23
CO2
22
STZ
22
Curcumin
22
cysteine
21
ACS
21
ACS
21
iodine
21
proline
21
bromide
20
Cardiol
20
His
20
retinoic acid
19
leucine
18
lysine
18
FAP
17
FAP
17
Neuronal
17
serine
17
vitamin D
17
copper
16
titanium
16
Eosin
16
silver
16
Hydroxyproline
16
Eosin
16
TEM
15
THP
13
nicotinamide
13
more...