Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:Q16637 (
SMA
)
8,107
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
SMA
8107
collagen
1783
smooth muscle actin
1685
Mol
807
alpha-smooth muscle actin
748
vimentin
596
fibronectin
564
SMN2
497
E-cadherin
489
Sep
483
SMN
431
CD34
330
desmin
320
Smad2
303
Smad3
279
TNF
265
CD31
243
IL-6
209
cytokine
206
type I collagen
178
catenin
169
connective tissue growth factor
144
p38
137
ERK
136
cytokeratin
132
telomeric
126
MAPK
126
ERK1
125
vascular endothelial growth factor
123
p53
122
proliferating cell nuclear antigen
121
caspase-3
117
S100
117
tumor necrosis factor
116
PDGF
113
TGF-beta
112
cage
110
AKT
110
Ki-67
110
calponin
109
more...
Disease
tumor
838
muscular atrophy
625
Spinal muscular atrophy
596
liver fibrosis
591
cancer
508
pulmonary fibrosis
295
carcinoma
167
cirrhosis
141
renal disease
135
diabetes
126
idiopathic pulmonary fibrosis
125
EMA
107
tumor growth
107
neuromuscular disorder
104
motor neuron disease
104
diabetic nephropathy
101
tumor progression
97
breast cancer
88
hypertension
88
ischemia
86
hepatocellular carcinoma
86
asthma
81
myocardial infarction
81
adenocarcinoma
74
hepatitis
70
atherosclerosis
69
metastases
69
Kugelberg-Welander
66
GSH
64
Werdnig-Hoffmann disease
64
amyotrophic lateral sclerosis
58
proteinuria
58
heart failure
53
lung disease
53
Renal fibrosis
52
sarcoma
51
liver disease
51
EMT
50
pancreatic cancer
46
tumorigenesis
44
more...
Symptom
weakness
197
pain
54
abdominal pain
28
hypotonia
27
respiratory distress
26
anesthesia
19
seizures
19
fatigue
16
tremor
16
thinning
15
vomiting
13
cough
13
collapse
12
hyperoxia
11
abdominal discomfort
10
dyspnea
9
epigastric pain
8
diarrhea
7
constipation
7
Scratch
7
nausea
6
functional recovery
6
chest pain
6
HSA
6
fasciculation
5
back pain
5
starvation
5
dystonia
5
angina
5
exhaustion
4
colic
4
bradykinesia
4
splenomegaly
4
joint stiffness
4
acidity
4
regurgitation
4
hepatomegaly
4
headache
4
Tongue fasciculations
3
abnormal gait
3
more...
Drug
ROS
60
Dermatol
46
Monit
37
MRC
30
Angiotensin II
21
Cardiovasc
18
Asthma
17
lysine
16
Fluorescein
16
BLM
12
CSF
12
ascorbate
11
TMS
10
Pirfenidone
10
CCL
9
Frontal
9
MAP
8
Taxol
7
Ethanol
7
Sorafenib
7
Albumin
6
CAM
6
Paraffin
6
Gel
6
IFN-gamma
6
Portal
6
Emodin
5
Gleevec
5
ADM
5
GEO
5
Activin
5
Emodin
5
Captopril
5
IL-2
5
Simvastatin
5
lactose
5
Imatinib
5
Leaf
5
DEX
4
Retinoic acid
4
more...
Enzyme
mitogen-activated protein kinase
349
ERK
322
alanine aminotransferase
171
aspartate aminotransferase
163
luciferase
124
focal adhesion kinase
123
superoxide dismutase
103
collagenase
91
protein kinase
90
caspase-3
83
alkaline phosphatase
65
AST
64
CD10
59
peroxidase
47
catalase
43
NADPH oxidase
43
NADPH oxidase
41
renin
39
MEK
39
MMP
35
reverse transcriptase
33
AMP-activated protein kinase
32
GSK
32
proteasome
28
lactate dehydrogenase
28
ACE
27
PARP
24
phosphatidylinositol 3-kinase
23
HK2
22
AMPK
21
protein kinase C
21
AMPK
21
ACS
21
ATPase
18
matrix metalloproteinase 2
17
RNA polymerase
17
caspase-1
16
trypsin
16
glutathione peroxidase
16
calcineurin
15
more...
Compound
Dec
488
Clin
365
DNA
267
TNF
265
glucose
231
oxygen
221
Collagen
156
creatinine
139
water
137
calcium
118
MTT
107
Vimentin
106
CCl4
101
urea
90
sodium
89
Ang II
88
nitrogen
76
ASA
72
phosphate
69
GSH
65
GSH
65
MDA
64
ANA
60
ANA
60
Hematoxylin
59
ethanol
58
hyaluronic acid
50
nitric oxide
47
arginine
44
tyrosine
41
PEG
39
acetate
38
methionine
37
iron
36
BLM
35
ATP
34
hydrogen
33
salt
32
PEG
30
zinc
29
more...