Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:Q16637 (SMA)
8,107 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
SMA 8107
collagen 1783
smooth muscle actin 1685
Mol 807
alpha-smooth muscle actin 748
vimentin 596
fibronectin 564
SMN2 497
E-cadherin 489
Sep 483
SMN 431
CD34 330
desmin 320
Smad2 303
Smad3 279
TNF 265
CD31 243
IL-6 209
cytokine 206
type I collagen 178
catenin 169
connective tissue growth factor 144
p38 137
ERK 136
cytokeratin 132
telomeric 126
MAPK 126
ERK1 125
vascular endothelial growth factor 123
p53 122
proliferating cell nuclear antigen 121
caspase-3 117
S100 117
tumor necrosis factor 116
PDGF 113
TGF-beta 112
cage 110
AKT 110
Ki-67 110
calponin 109
more...
Disease
tumor 838
muscular atrophy 625
Spinal muscular atrophy 596
liver fibrosis 591
cancer 508
pulmonary fibrosis 295
carcinoma 167
cirrhosis 141
renal disease 135
diabetes 126
idiopathic pulmonary fibrosis 125
EMA 107
tumor growth 107
neuromuscular disorder 104
motor neuron disease 104
diabetic nephropathy 101
tumor progression 97
breast cancer 88
hypertension 88
ischemia 86
hepatocellular carcinoma 86
asthma 81
myocardial infarction 81
adenocarcinoma 74
hepatitis 70
atherosclerosis 69
metastases 69
Kugelberg-Welander 66
GSH 64
Werdnig-Hoffmann disease 64
amyotrophic lateral sclerosis 58
proteinuria 58
heart failure 53
lung disease 53
Renal fibrosis 52
sarcoma 51
liver disease 51
EMT 50
pancreatic cancer 46
tumorigenesis 44
more...
Symptom
weakness 197
pain 54
abdominal pain 28
hypotonia 27
respiratory distress 26
anesthesia 19
seizures 19
fatigue 16
tremor 16
thinning 15
vomiting 13
cough 13
collapse 12
hyperoxia 11
abdominal discomfort 10
dyspnea 9
epigastric pain 8
diarrhea 7
constipation 7
Scratch 7
nausea 6
functional recovery 6
chest pain 6
HSA 6
fasciculation 5
back pain 5
starvation 5
dystonia 5
angina 5
exhaustion 4
colic 4
bradykinesia 4
splenomegaly 4
joint stiffness 4
acidity 4
regurgitation 4
hepatomegaly 4
headache 4
Tongue fasciculations 3
abnormal gait 3
more...
Drug
ROS 60
Dermatol 46
Monit 37
MRC 30
Angiotensin II 21
Cardiovasc 18
Asthma 17
lysine 16
Fluorescein 16
BLM 12
CSF 12
ascorbate 11
TMS 10
Pirfenidone 10
CCL 9
Frontal 9
MAP 8
Taxol 7
Ethanol 7
Sorafenib 7
Albumin 6
CAM 6
Paraffin 6
Gel 6
IFN-gamma 6
Portal 6
Emodin 5
Gleevec 5
ADM 5
GEO 5
Activin 5
Emodin 5
Captopril 5
IL-2 5
Simvastatin 5
lactose 5
Imatinib 5
Leaf 5
DEX 4
Retinoic acid 4
more...
Enzyme
mitogen-activated protein kinase 349
ERK 322
alanine aminotransferase 171
aspartate aminotransferase 163
luciferase 124
focal adhesion kinase 123
superoxide dismutase 103
collagenase 91
protein kinase 90
caspase-3 83
alkaline phosphatase 65
AST 64
CD10 59
peroxidase 47
catalase 43
NADPH oxidase 43
NADPH oxidase 41
renin 39
MEK 39
MMP 35
reverse transcriptase 33
AMP-activated protein kinase 32
GSK 32
proteasome 28
lactate dehydrogenase 28
ACE 27
PARP 24
phosphatidylinositol 3-kinase 23
HK2 22
AMPK 21
protein kinase C 21
AMPK 21
ACS 21
ATPase 18
matrix metalloproteinase 2 17
RNA polymerase 17
caspase-1 16
trypsin 16
glutathione peroxidase 16
calcineurin 15
more...
Compound
Dec 488
Clin 365
DNA 267
TNF 265
glucose 231
oxygen 221
Collagen 156
creatinine 139
water 137
calcium 118
MTT 107
Vimentin 106
CCl4 101
urea 90
sodium 89
Ang II 88
nitrogen 76
ASA 72
phosphate 69
GSH 65
GSH 65
MDA 64
ANA 60
ANA 60
Hematoxylin 59
ethanol 58
hyaluronic acid 50
nitric oxide 47
arginine 44
tyrosine 41
PEG 39
acetate 38
methionine 37
iron 36
BLM 35
ATP 34
hydrogen 33
salt 32
PEG 30
zinc 29
more...